Cases reported "Poxviridae Infections"

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1/4. A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values.

    monkeypox virus disease is a rare zoonosis that until recently was limited to Central africa. We describe the clinical features of the third child in the united states reported with this newly emerging infection. This child was part of a large cluster of individuals in the Midwest infected by prairie dogs that had contracted the virus when housed with infected small mammals imported from africa. The differential and laboratory diagnoses and the difficulty finding physicians and nurses to care for this patient are discussed.
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2/4. Human sealpox resulting from a seal bite: confirmation that sealpox virus is zoonotic.

    The case of a marine mammal technician who sustained a seal-bite to the hand that produced a lesion clinically very similar to orf is described. sequence analysis of the viral dna amplified from the lesion by the polymerase chain reaction indicated that it was sealpox virus in origin. This is the first report providing unequivocal evidence that sealpox may be transmitted to humans and causes lesions very similar to orf.
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3/4. Human poxvirus disease after smallpox eradication.

    A 5-year-old boy living in a small camp in the rural Ivory Coast had a disease resembling smallpox. This occurred 4 years after smallpox had been eradicated from the Ivory Coast and 1.5 years after the last case of smallpox was detected in West and Central africa. Clinical, serological, and epidemiological evidence indicated this disease was probably monkeypox, a poxvirus of the variola/vaccina subgroup. A serologic survey of poxvirus antibodies in the wild animal population detected neutralizing antibodies in rodents, larger mammals, primates, and birds. The laboratory and ecological characteristics of poxviruses require further elucidation, especially those which have been found in animals near human monkeypox cases.
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4/4. Human monkeypox transmitted by a chimpanzee in a tropical rain-forest area of Zaire.

    A case of monkeypox infection in a six-month-old baby girl who had been bitten by a wild chimpanzee in Kivu, Zaire, was investigated. The child had not been exposed to any monkeypox-like disease and no cases of such disease had occurred in the surrounding area during previous months. The time of onset of rash was consistent with the virus having been transmitted from the chimpanzee. However, it is still not known whether chimpanzees and other primates or lower mammals are the primary reservoir of monkeypox infection.
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