Cases reported "Prurigo"

Filter by keywords:



Filtering documents. Please wait...

1/3. thalidomide in the management of epidermolysis bullosa pruriginosa.

    epidermolysis bullosa (EB) pruriginosa is a distinctive clinical subtype of dystrophic EB. We report a patient with dominant dystrophic EB pruriginosa, who had an excellent response to systemic thalidomide treatment. The mechanism of action of thalidomide in the management of pruriginous disorders is not yet completely understood. Most recent studies point towards an immunomodulatory action of thalidomide that may suppress excessive production of tumour necrosis factor-alpha and may downregulate certain cell surface adhesion molecules involved in leucocyte migration.
- - - - - - - - - -
ranking = 1
keywords = epidermolysis bullosa, epidermolysis, bullosa
(Clic here for more details about this article)

2/3. Linear prurigo simulating dermatitis artefacta in dominant dystrophic epidermolysis bullosa.

    We report a family suffering from dominant dystrophic epidermolysis bullosa, in whom linear lichenified lesions and troublesome pruritus were prominent features. We consider that this clinical picture may constitute a separate subtype of this disorder.
- - - - - - - - - -
ranking = 1.232326210133
keywords = epidermolysis bullosa, epidermolysis, bullosa
(Clic here for more details about this article)

3/3. epidermolysis bullosa pruriginosa.

    epidermolysis bullosa (EB) pruriginosa is a rare clinical subset of dystrophic EB, characterized by marked itching and presence of prurigo-like or lichenoid features. In order to further delineate the phenotype and understand the pathogenesis of this disorder, the clinical, histological and ultrastructural findings of a 19-year-old patient presenting a typical form of EB pruriginosa are described. The prevalence of papular itchy lichenoid lesions, signs of scratching and paucity of blisters at the time of clinical examination may result in incorrect diagnosis and treatment. Microscopic studies of the lesions show the typical findings of dystrophic EB associated with an unusually high density of collagen bundles and absence of elastic fibres in the upper dermis. Itching lichenoid lesions of EB pruriginosa could represent an abnormal dermal reactivity of some patients to their inherited bullous disorder.
- - - - - - - - - -
ranking = 0.070695159468068
keywords = bullosa
(Clic here for more details about this article)


Leave a message about 'Prurigo'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.