Cases reported "Psoriasis"

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1/5. incidence of skin cancer in Japanese psoriatic patients treated with either methoxsalen phototherapy, Goeckerman regimen, or both therapies. A 10-year follow-up study.

    To determine the long-term cutaneous side effects of methoxsalen phototherapy (PUVA) and Goeckerman regimen, a total of 151 Japanese psoriatic patients treated with PUVA, Goeckerman regimen, or both therapies in our department from 1976 to 1986 were evaluated for skin cancers. Sixty-seven patients had been treated with PUVA, 43 with Goeckerman regimen, and 41 with both therapies. One patient alone (62-year-old man) developed squamous cell carcinoma on the leg with cumulative ultraviolet A (UVA) dose of only 51 joules/cm2, he had a history of treatment with superficial x-ray therapy to this area 30 years prior to PUVA. The cancer was detected after 1.4 years of PUVA treatment. However, other patients at follow-up, even those who had received a cumulative dose of UVA of more than 1000 joules/cm2, had no skin cancer after more than 2 years. This report in Japanese patients confirms that only previous exposure to other risk factors such as ionizing radiation appears to be a most important factor for skin cancer formation in PUVA-treated Japanese patients.
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ranking = 1
keywords = x-ray
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2/5. skin cancer caused by grenz rays.

    A 30-year-old woman developed chronic radiodermatitis and five squamous cell carcinomas within 7 years following a 16-year period of repeated grenz irradiations given to her psoriasis. The estimated cumulative dose of grenz radiation was approximately 3,000 rads (r) to each treated area. This case, illustrating a rather underestimated carcinogenic potential of grenz rays, is interpreted in light of the available literature on the subject. The technical bases of grenz ray therapy are also briefly reviewed.
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ranking = 207838.46210281
keywords = grenz
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3/5. Psoriatic arthritis with C-1-C-2 subluxation as a neurosurgical complication.

    A 39-year-old man presented with a 10-year history of psoriatic arthritis, and more recently a progressive high cervical myelopathy. The development of the myelopathy syndrome was unassociated with trauma or any other specific inciting cause. Cervical spine x-rays demonstrated a significant atlantoaxial subluxation. Other x-ray features of the spine met the criteria for diagnosis of psoriatic spondylitis. The association of a high cervical myelopathy with atlantoaxial subluxation in psoriatic spondylitis is rare. Conversely, atlantoaxial subluxation without high cervical myelopathy has been reported in 45% of cases of psoriatic spondylitis. The authors report this case with a review of the diagnosis, possible pathogenesis, and treatment of atlantoaxial subluxation in psoriatic spondylitis.
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ranking = 2
keywords = x-ray
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4/5. Successful treatment of psoriasis of the nails.

    psoriasis of fingernails and toenails presents a challenge that has not been met by the available therapeutic modalities. Three cases of treatment with x-ray therapy of varying intensities are presented herein. Cure was acheived in all three cases with no x-ray sequelae.
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ranking = 2
keywords = x-ray
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5/5. Squamous cell carcinoma of the scrotum associated with human papillomaviruses.

    A 53-year-old man presented with recurrent squamous cell carcinoma, and dysplasia of the scrotum and penis. risk factors included psoralen and ultraviolet radiation therapy for psoriasis, and x-ray therapy for primary lymphoma of the groin. Three different human papillomavirus types were documented using the polymerase chain reaction in distinct anatomical areas. The scrotal carcinoma was associated with human papillomavirus type 18, while regions of dysplasia contained either type 18, 16 or 6/11. diagnosis of squamous dysplasia and carcinoma of the scrotum in men with psoriasis is complicated by chronic active inflammation, and molecular biological methods may be necessary to detect human papillomavirus infected cells.
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ranking = 1
keywords = x-ray
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