Cases reported "Pulmonary Edema"

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11/13. Pathophysiologic alterations in endotoxemia. Similarities to an animal model.

    The validity of animal models of human sepsis has been questioned. We describe a patient who experienced a short episode of endotoxemia (? bacteremia) with resultant pulmonary hypertension, pulmonary edema from increased alveolar capillary membrane permeability, hypoxemia, hypotension, and relative leukopenia, which mimics the pathophysiologic changes noted following infusion of pseudomonas bacteria into awake sheep. The similarity of abnormalities and their resolution suggests that pseudomonas infusion in sheep is a valid experimental model of human septic shock.
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keywords = animal
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12/13. A case of noncardiogenic pulmonary edema by ethanolamine oleate.

    Endoscopic injection of sclerosing agents is a strategy for control of esophageal varix bleeding. Five percent solution of ethanolamine oleate(EO) has been used as sclerosing agent. It is well known that intravascular injection of oleic acid induces acute respiratory failure in animal models. However, EO-induced noncardiogenic pulmonary edema has not been reported in human. We report a case of noncardiogenic pulmonary edema developed after therapeutic trial of EO as sclerosing agent for esophageal varix.
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keywords = animal
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13/13. Rocket propellant inhalation in the Apollo-Soyuz astronauts.

    Acute exposure to monomethylhydrazine and dinitrogen tetroxide, the principal toxic irritants in rocket fuels, is described with particular attention to the development of pulmonary edema as a herbinger of more severe central nervous system toxicity. An acute respiratory embarrassment is documented and possible means of therapy based on animal experimental models is suggested. Early clinical and radiographic examination as a baseline for further evaluation is essential, with follow-up radiographs recommended for assessment of possible developing chronic lung disease.
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keywords = animal
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