1/6. Neurologic illness following post-exposure prophylaxis with purifiled chick embryo cell antirabies vaccine.Clinical details of a neurologic illness simultating Guillain Barre syndrome developing in a patient after post-exposure prophylaxis with purified chick embryo cell (PCEC) anti-rabies vaccine is reported. Neurologic complication following PCEC vaccination has not been reported earlier.- - - - - - - - - - ranking = 1keywords = embryo (Clic here for more details about this article) |
2/6. Rabies in a Thai child treated with the eight-site post-exposure regimen without rabies immune globulin.We report the case of a 7-year-old Thai girl that was bitten by a dog. She received prompt wound care followed by eight-site intradermal post-exposure rabies schedule using purified chick embryo vaccine. Treatment followed WHO recommendations for desperate situations where no rabies immune globulin (RIG) is available. The patient died 15 days later with classical symptoms and signs of encephalitic rabies.- - - - - - - - - - ranking = 0.2keywords = embryo (Clic here for more details about this article) |
3/6. Bilateral neuro-retinitis following chick embryo cell anti-rabies vaccination--a case report.BACKGROUND: The optic nerve is rarely involved after sheep brain anti-rabies vaccination in the form of retrobulbar neuritis or papillitis. Bilateral neuroretinitis after chick embryo cell antirabies vaccination has not been reported. CASE PRESENTATION: We report the case of a 56 year old male who developed bilateral neuro-retinitis following three injections of antirabies vaccine prepared from the chick embryo. CONCLUSION: The chick embryo cell antirabies vaccine can cause bilateral neuroretinits which has not been reported previously.- - - - - - - - - - ranking = 1.4keywords = embryo (Clic here for more details about this article) |
4/6. Confirmed rabies exposure during pregnancy: treatment with human rabies immune globulin and human diploid cell vaccine.A review of the literature shows 24 cases of pregnant human exposure to rabies virus through confirmed rabid animal bites. Historically, these patients received passive immunization with equine rabies immunoglobulin and/or purified vero cell vaccine or duck embryo vaccine. With the recent development of human-derived rabies vaccines, we report an additional case of human gestational rabies exposure, which was treated with human rabies immune globulin and human diploid cell vaccine.- - - - - - - - - - ranking = 0.2keywords = embryo (Clic here for more details about this article) |
5/6. Failure of rabies postexposure treatment in thailand.Three failures of postexposure rabies treatment using imported purified duck embryo cell and Vero cell rabies vaccines are reported from thailand. Reference is made to eight additional previously reported Thai patients, six of whom had received human diploid cell vaccine. An analysis of these cases reveals that there were serious flaws in management in all of these patients. It is stressed that 45% of human rabies deaths in thailand occur within 20 days of being bitten and 71% are dead within 28 days. This short incubation period does not allow much time to start immunotherapy. Of Bangkok dogs found to have rabies at autopsy, approximately 8% have a rabies immunization history. Once a dog has bitten a patient immunotherapy should not be delayed in countries with a high incidence of dog rabies. patients with chronic disease, alcoholics and drug addicts may have an impaired immune response to postexposure rabies vaccines.- - - - - - - - - - ranking = 0.2keywords = embryo (Clic here for more details about this article) |
6/6. Clinical use of human globulin immune to rabies virus.Studies of human globulin immune to rabies virus before licensure showed that it suppressed active antibody responses when individuals received 16 doses of duck embryo vaccine but not when they received 23 doses of duck embryo vaccine. Prospective surveillance of use of human globulin immune to rabies virus since licensure in 1974 has revealed that 40% of persons who receive 14-16 doses of duck embryo vaccine have low or undetectable antibody responses 30-90 days after initiation of the series. Ten percent of individuals receiving 21-23 doses of duck embryo vaccine have inadequate antibody responses, a percentage not significantly different from that found in recipients of 14 doses of vaccine alone. Human globulin immune to rabies virus has also been used for treatment of one case of clinical human rabies; this use was based on the observation that antibodies to rabies virus in serum do not develop until after the seventh day of clinical illness, and antibodies are absent from spinal fluid as long as 19 days after onset of symptoms. intracranial pressure and neurological function remained stable after administration of human globulin immune to rabies virus, but two days after initiation of therapy, the patient died of progressive pulmonary dysfunction and tension pneumothorax.- - - - - - - - - - ranking = 0.8keywords = embryo (Clic here for more details about this article) |