1/10. retinitis pigmentosa associated with peripheral sea fan neovascularization.PURPOSE: To describe a case with retinitis pigmentosa associated with sea fan type retinal neovascularization. methods: Complete ocular examination including fluorescein angiography was performed in a 9-year-old girl. RESULTS: Ophthalmoscopically, in addition to arteriolar narrowing and bone corpuscular pigmentation of both retinae, a vascular lesion with surrounding intraretinal exudation was noted in the upper equatorial region of the right eye. On fluorescein angiography, the lesion stained in the form of a sea fan neovascularization. CONCLUSION: Sea fan type of neovascularization can be seen in association with retinitis pigmentosa. fluorescein angiography is important in identifying the exact nature of such a lesion.- - - - - - - - - - ranking = 1keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
2/10. Midperipheral mottling pigmentation with familial choroidal osteoma.PURPOSE: To describe a rare presentation of familial choroidal osteoma in two siblings. methods: The clinical findings in two siblings over 4 years' follow-up. RESULTS: Two brothers (15 and 12 years old) had bilateral choroidal osteomas. Both had bilateral peripapillary yellowish-white lesions and midperipheral mottling pigment appearance, which are not seen in sporadic cases. Extensive midperipheral area with mottling pigment appearance was noted by fluorescein angiography (FA) as scattered multiple hyperfluorescent dots. The yellowish-white lesions showed diffuse hyperfluorescence with FA and hypofluorescence with indocyanine green angiography (ICG). ICG also revealed irregular hyperfluorescent areas within the tumor, indicating abnormal choroidal vessels on the tumor. In the left eye of the younger brother, the subretinal fibrosis due to choroidal neovascularization superior to the macula extended down toward the foveal region over 2 years, resulting in visual deterioration. CONCLUSION: The midperipheral mottling pigment appearance of familial choroidal osteoma cases is unique and different from most sporadic cases, suggesting that familial choroidal osteoma might have separate etiologic or modified factors.- - - - - - - - - - ranking = 0.077020045785897keywords = neovascularization (Clic here for more details about this article) |
3/10. Multifocal hypopigmented retinal pigment epithelial lesions in incontinentia pigmenti.BACKGROUND: incontinentia pigmenti (IP) can manifest with retinal detachment in children and can simulate retinoblastoma. The authors report a clinicopathologic correlation of IP and illustrate the retinal pigment epithelium (RPE) alterations that may be useful in establishing the diagnosis. methods: A 30-month-old reportedly healthy girl developed strabismus and was discovered to have total retinal detachment in the left eye. Intraocular calcification was found on ultrasonography and computed tomography, suggestive of retinoblastoma. RESULTS: ophthalmoscopy of the right eye revealed sector distribution of approximately 70 elongated, linear hypopigmented lesions of the RPE located in the peripheral superotemporal, inferotemporal, and superonasal quadrants and measuring 300 microm or less in basal dimension. The left eye had a total retinal detachment, vitreous traction, perivascular exudation, and iris neovascularization. Despite the lack of medical history in this patient, skin examination revealed classic cutaneous findings of IP The enucleated left globe displayed tractional retinal detachment with vitreoretinal neovascularization and nonspecific RPE papillary proliferation. Scattered minor foci of intraretinal calcification were observed. There was no sign of retinoblastoma. CONCLUSIONS: IP can closely simulate retinoblastoma with retinal detachment and minor intraocular calcification. In this case, the classic cutaneous manifestations combined with the fine linear hypopigmented RPE foci were important in suggesting the diagnosis of IP.- - - - - - - - - - ranking = 0.61489977107052keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
4/10. Retinal hemangioma-like lesions in eyes with retinitis pigmentosa.The authors report two patients with bilateral vascular masses of the peripheral retina associated with primary pigmentary dystrophy of the retina (retinitis pigmentosa). Although they are most similar to the retinal capillary hemangiomas of von Hippel, the affected patients had no clinical history or clinical findings suggestive of that syndrome. They differ from the calcified retinal hamartomas that have been associated with retinitis pigmentosa because they do not show the extensive telangiectasia and exudation seen with the exudative retinopathy that has been described with retinitis pigmentosa. They do not show the fluorescein angiographic pattern that characterizes peripheral choroidal neovascularization. Their main complication seems to be vitreous hemorrhage rather than exudative retinopathy. The authors discuss the possible relationship of these acquired retinal vascular masses to the retinitis pigmentosa.- - - - - - - - - - ranking = 0.077020045785897keywords = neovascularization (Clic here for more details about this article) |
5/10. Bilateral optic disc neovascularization in association with retinitis pigmentosa.Bilateral neovascularization of the optic disc developed in a 16-year-old Hispanic girl with retinitis pigmentosa. The neovascularization regressed in both eyes over 1 year without treatment. Ocular and systemic evaluation failed to reveal a recognized cause for the neovascularization. To our knowledge this is only the third case reported of this unusual association.- - - - - - - - - - ranking = 0.53914032050128keywords = neovascularization (Clic here for more details about this article) |
6/10. Neovascularization of the optic disk associated with atypical retinitis pigmentosa.A 32-year-old man with atypical retinitis pigmentosa developed bilateral neovascularization of the optic disk. One year after the diagnosis, vitreous hemorrhage occurred in one eye. Panretinal photocoagulation of this eye resulted in some regression of the neovascularization.- - - - - - - - - - ranking = 0.15404009157179keywords = neovascularization (Clic here for more details about this article) |
7/10. retinitis pigmentosa and retinal neovascularization.Four patients with retinitis pigmentosa and either disc or peripheral retinal neovascularization with recurrent vitreous hemorrhage are described. One patient with peripheral retinal neovascularization also had rubeosis and neovascular glaucoma. The effects of relative hyperoxia on the retinal microcirculation in retinitis pigmentosa as well as intraocular inflammation may account for such changes. Laser photocoagulation appears effective in preventing vitreous hemorrhage in these patients, but systemic administration of corticosteroids did not cause the new vessels to regress.- - - - - - - - - - ranking = 3.2272783517077keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
8/10. retinitis pigmentosa and retinal neovascularization: a case report.A 21-year-old white man with retinitis pigmentosa was found to have an isolated patch of retinal neovascularization. Ocular and systemic evaluation failed to reveal a recognized cause for the neovascularization. This case is felt to represent the unusual association of retinitis pigmentosa and retinal neovascularization.- - - - - - - - - - ranking = 3.3042983974936keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
9/10. Clinical features of autosomal dominant retinitis pigmentosa with rhodopsin gene codon 17 mutation and retinal neovascularization in a Japanese patient.A 49-year-old Japanese man had autosomal dominant retinitis pigmentosa with a point mutation in codon 17 of the rhodopsin gene, resulting in a threonine-to-methionine change, and retinal neovascularization in both eyes. Pigmentary degeneration mainly in the inferior area of the fundus, and severe loss in the upper portion of the visual field were observed. Moderately preserved rod and cone functions were demonstrated by electroretinograms. These findings differed from those of Japanese and white patients with autosomal dominant retinitis pigmentosa with a codon 347 mutation and were almost the same as those of white patients with the codon 17 mutation. Our study indicates that phenotypic similarities exist among patients with the same mutation, but of different racial backgrounds. The neovascularization in the right eye diminished over a two-year period in conjunction with the progression of retinal degeneration.- - - - - - - - - - ranking = 2.766418672209keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
10/10. retinitis pigmentosa with recurrent vitreous hemorrhage.We observed recurrent vitreous hemorrhage in two patients with retinitis pigmentosa: a 41-year-old female and a 49-year-old male. At age 41, the first patient had diffuse capillary dilatation, macular microaneurysms, and paramacular macroaneurysms in the right eye. At age 47, similar retinal vascular lesions and disc neovascularization developed in the left eye followed by recurrent vitreous hemorrhage. The retinal microvascular changes and vitreous hemorrhages subsided spontaneously during the ensuring 4 years. In the second case, recurrent vitreous hemorrhage developed in the right eye. Funduscopy and fluorescein angiography at age 49 revealed no angiopathy. However, 2 years later we detected retinal neovascularization in the macula and an avascularity in the peripheral retina in the right eye. Subretinal exudate or retinal detachment was consistently absent in both cases.- - - - - - - - - - ranking = 0.61489977107052keywords = retinal neovascularization, neovascularization (Clic here for more details about this article) |
| | Next -> |