11/20. Chronic superficial pyoderma of the face: an unusual male case of rosacea fulminans.A 62-year-old Japanese male developed acneiform papules on the face in November of 2002. The eruptions progressed to exudative erythema with central necrosis, and then to thick-crusted superficial abscesses in a short period. The shallow ulcers exposed by removal of the crusts and abscesses immediately re-epithelized without leaving scars. The histology of the eruption was a dense infiltration of neutrophils associated with granulomatous changes in the upper to middle dermis. histology of the tiny white particles in the abscess showed an irregularly proliferated mass of keratinocytes including accumulated neutrophils. The skin lesions resisted intravenous injection of antibiotics but responded to systemic administration of a corticosteroid agent. colchicine did not work well, but the additional administration of etretinate was effective. The patient is currently receiving combined therapy with prednisolone and etretinate, but eruptions are still episodically observed. We diagnosed this case as an unusual male case of rosacea fulminans.- - - - - - - - - - ranking = 1keywords = acne (Clic here for more details about this article) |
12/20. Autosomal dominant familial chronic mucocutaneous candidiasis associated with acne rosacea.INTRODUCTION: Autosomal dominant chronic mucocutaneous candidiasis (CMC) without endocrinopathy (OMIM 114580) is a well-described entity. The associations recorded with this disorder to date are intercellular adhesion molecule-1 (ICAM-1) deficiency and hyper-immunoglobulin e syndrome. CLINICAL PICTURE: We report a new association in a family (mother and nonidentical twin sons) where acne rosacea is a prominent feature together with CMC. In addition, antibodies to thyroid microsomal and antiparietal cell were also isolated. The autoantibodies might be associated with a current "latent" endocrinopathy in particular autoimmune thyroiditis. TREATMENT: The patient was treated with intermittent pulses of itraconazole for the candidiasis and doxycycline initially before being substituted with isotretinoin 6 months later for the rosacea. OUTCOME: The patient's candidiasis responded well and has been in remission for 3 months while his rosacea continues to improve.- - - - - - - - - - ranking = 5keywords = acne (Clic here for more details about this article) |
13/20. Pediatric ocular acne rosacea: long-term treatment with systemic antibiotics.PURPOSE: To report our experience with four cases of pediatric ocular acne rosacea, including responses to long-term systemic treatment. DESIGN: Retrospective interventional case series. methods: The medical records of four consecutive cases diagnosed with pediatric ocular acne rosacea over a period of 36 months were reviewed. Diagnostic criteria were meibomian gland dysfunction, blepharitis, lid margin telangiectasia, punctate superficial keratopathy, and conjunctival hyperemia with or without inferior corneal vascularization. RESULTS: The patients, aged between four and 12, were all females with bilateral disease. Meibomitis, blepharitis, conjunctival hyperemia, and punctuate epitheliopathy was evident in each case. Cutaneous involvement was seen in two cases (50%), and limbal vascularization with subepithelial or stromal infiltrates was present in three cases (75%). One case showed corneal ulceration at presentation. All four children received systemic doxycycline or erythromycin for at least 12 months and showed considerable improvement within the first month of therapy. No recurrence was noted within the mean 25.5 months of follow-up. None of the girls experienced any side effects during the long treatment duration. CONCLUSIONS: Ophthalmologists should consider acne rosacea as a potential diagnosis for any child who has any combination of meibomian disease, chronic blepharitis, recurrent chalazia, and chronic symptoms of photophobia, ocular irritation, and redness that does not respond to routine medical treatment. Such patients respond very well to long-term treatment with systemic erythromycin/doxycycline.- - - - - - - - - - ranking = 7keywords = acne (Clic here for more details about this article) |
14/20. delusions of disfigurement in a woman with acne rosacea.A 36-year-old woman with newly diagnosed acne rosacea is presented. Her skin changes were noticeable only under closest scrutiny, but she quit her job, became despondent about her acne, and developed suicidal ideation. The diagnosis and treatment of this patient allow a broader discussion of the somatically focused patient whose ideation reaches delusional intensity.- - - - - - - - - - ranking = 6keywords = acne (Clic here for more details about this article) |
15/20. Granulomatous acne rosacea of the eyelids.We describe the clinicopathologic features of the papular form of granulomatous acne rosacea of the eyelids. This unusual cutaneous disorder is typified by painless eruptions of reddish to yellowish brown, occasionally ulcerative papules symmetrically distributed around the eyelids, lower part of the forehead, nasolabial folds, and upper lip. Histopathologically, the lesions display caseating and noncaseating dermal granulomas that mimic those seen in tuberculosis, tuberculoid leprosy, sarcoidosis, and other diseases. The disorder responds well to systemic tetracycline therapy but may involute spontaneously during a period of months to years. The distinction of this disorder from other dermal granulomatous diseases, such as tuberculosis, leprosy, syphilis, and foreign bodies, is important because of the different therapeutic implications.- - - - - - - - - - ranking = 5keywords = acne (Clic here for more details about this article) |
16/20. Nasal septal carcinoma masquerading as acne rosacea.A 57-year-old woman developed diffuse erythema of the nose that had been diagnosed as acne rosacea for 18 months. biopsy showed infiltration deep in the nasal skin of a squamous cell carcinoma that extended from the nasal septum. Nasal septal tumors are rare; the most common is squamous cell carcinoma.- - - - - - - - - - ranking = 5keywords = acne (Clic here for more details about this article) |
17/20. Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment.We report the observation of delayed wound healing and keloid formation in three patients, following dermabrasion or argon laser treatment administered while they were receiving isotretinoin for acne or rosacea.- - - - - - - - - - ranking = 1keywords = acne (Clic here for more details about this article) |
18/20. rhinophyma in a negro: case report.A case of rhinophyma in a negro patient is reported. The cause of rhinophyma and its association with acne rosacea is discussed. It is suggested that racial factors may be relevant in this incompletely understood condition.- - - - - - - - - - ranking = 1keywords = acne (Clic here for more details about this article) |
19/20. Acne rosacea with keratitis in childhood.We present three cases of acne rosacea keratitis that developed in childhood. All three children were prepubescent and demonstrated characteristic dermatologic findings involving the nose, cheeks, and/or chin. The patients had complained of ocular irritation for at least 6 months, and in one case symptoms were reported by the family to have occurred intermittently since age 4 years. All three children showed evidence of meibomian gland inflammation; two patients demonstrated bilateral keratitis, the third had only unilateral involvement. In each case, oral tetracycline hydrochloride or doxycycline hyclate was necessary to relieve symptoms. rosacea keratitis should be considered in the differential diagnosis of chronic keratoconjunctivitis during childhood.- - - - - - - - - - ranking = 1keywords = acne (Clic here for more details about this article) |
20/20. Rosaceous lymphedema: a rare variant of a common disorder.Rosaceous lymphedema is considered to be a rare and disfiguring variant of acne rosacea. Cases remain difficult to treat and can challenge afflicted patients both cosmetically and psychologically. We describe an unusual presentation of rosaceous lymphedema and review the differential diagnosis of persistent facial edema.- - - - - - - - - - ranking = 1keywords = acne (Clic here for more details about this article) |
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