Cases reported "Salivary Gland Diseases"

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1/32. Necrotizing sialometaplasia.

    Two cases of necrotizing sialometaplasia are reported together with a review of the literature. This self-limiting benign lesion is easily confused with malignant tumors. The lesions are characterized histologically by an extensive necrosis of the salivary gland tissue together with squamous metaplasia of the ducts. The present report of two females who had intense pain in the initial phase differs from previous reports concerning age and symptoms. The importance of rather extensive biopsy specimens is stressed. Antibiotic treatment appears to be insignificant. A clinical history of allergy and a dominance of eosinophilic granulocytes in the inflammatory exudate in both cases may indicate an allergic etiology.
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keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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2/32. Necrotizing sialometaplasia. Report of a case.

    Necrotizing sialometaplasia occurred in a 46-year-old woman. This is an uncommon benign disease that typically begins with an ulcerated lesion on the hard palate and surrounding tissues. Clinical and microscopic findings show obvious similarity with a malignant neoplasm. Necrotizing sialometapiasis is a benign minor salivary gland disease. It is important since it may easily be confused with squamous cell carcinoma and mucoepidermoid carcinoma.
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ranking = 0.84658130746333
keywords = sialometaplasia
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3/32. Necrotizing sialometaplasia of parotid gland: a possible vasculitic cause.

    Necrotizing sialometaplasia at the parotid gland location is rare and simulates malignant disease. If it is seen at this location, the causes may be previous dental or parotid gland surgical procedures, which result in blood vessel injuries and thrombosis. We report a parotid gland necrotizing sialometaplasia of a 17-year-old girl, possibly caused by primary vascular damage or vasculitis.
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ranking = 1.1693162614927
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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4/32. Antineutrophil cytoplasmic autoantibody-associated vasculitis presenting as sjogren's syndrome.

    A 63-year-old woman, in whom a diagnosis of sjogren's syndrome was initially made, proved to have systemic vasculitis with salivary gland involvement and necrotizing and crescentic glomerulonephritis. Antineutrophil cytoplasmic autoantibodies (ANCA) against myeloperoxidase were positive. ANCA-associated vasculitis should be considered in the differential diagnosis of sjogren's syndrome. A positive finding on immunoassay for ANCA against myeloperoxidase or proteinase 3 may help establish the diagnosis.
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ranking = 7.6488142772631E-5
keywords = necrotizing
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5/32. Necrotizing sialometaplasia of the mandible.

    A brief review of the literature on necrotizing sialometaplasia has been presented. A patient with necrotizing sialometaplasia of the retromolar pad is reported. This is the first such lesion to be described in an oral site other than the palate. Clinical, histologic, and etiologic aspects of the lesion have veen discussed.
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ranking = 1.3227349540293
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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6/32. NECROTIZING SIALOMETAPLASIA.

    Nonhealing palatal ulcerations in two white male patients, one 50 and another 58 years of age, were clinically suspected of being malignant, even after the initial biopsies were negative. Second biopsies in each case confirmed the original opinions, but the lesions were diagnosed specifically as "necrotizing sialometaplasia". This is an interesting condition of uncertain etiology that can mimic cancer, both clinically and microscopically. The condition heals spontaneously. It should be considered in a differential diagnosis of suspicious lesions of the palate.
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ranking = 0.32273495402933
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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7/32. Necrotizing sialometaplasia. A review of the literature and report of two additional cases.

    Necrotizing sialometaplasia is a nonneoplastic, inflammatory, variably ulcerated, occasionally bilateral, self-healing lesion of human salivary glands which is often confused clinically and histologically with squamous cell or mucoepidermoid carcinoma. On the basis of thirty-three documented cases, the lesion occurs primarily in the minor salivary glands of the palate (87.9 percent), with 63.6 percent arising in the fifth and sixth decades (average age 46.0 years, range 22 to 68 years). There is a marked predilection for males (ratio of males to females. 2.7:1) and a questionable predominance in Caucasians (60.6 percent). Numerous etiologic factors have been proposed; however, on the basis of previous animal experimentation, the lesion appears to be infarctive in nature.
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ranking = 0.84658130746333
keywords = sialometaplasia
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8/32. Necrotizing sialometaplasia affecting the minor labial glands.

    A case of necrotizing sialometaplasia of the lower lip, a previously unreported location for this lesion, is presented. In the past, other cases of this benign process occuring in this site may have been confused with squamous-cell or mucoepidermoid carcinoma. In order to arrive at the correct diagnosis, an ample biopsy of the lesion is mandatory.
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keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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9/32. Necrotizing sialometaplasia.

    An example of palatal necrotizing sialometaplasia is presented, and the clinical and microscopic features suggestive of squamous-cell carcinoma and mucoepidermal carcinoma are noted. The patient's health status, as shown by a rather thorough work-up, was unremarkable during the period which would seem to preclude a systemic etiology of this disease. The resolution of the lesion with minimal therapy is documented.
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keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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10/32. Necrotizing sialometaplasia.

    Three additional cases of necrotizing sialometaplasia are discussed. Clinical appearance of the lesion is not diagnostic. microscopy shows pseudoepitheliomatous hyperplasia, squamous metaplasia, and acinar necrosis. No atypia is seen. Mucoepidermoid and squamous cell carcinoma are frequent wrong diagnoses. All reported lesions have healed without recurrence regardless of therapy.
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ranking = 1
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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