1/11. Lobular carcinoma of the breast metastatic to the oral cavity mimicking polymorphous low-grade adenocarcinoma of the minor salivary glands.The oral cavity is a rare site of metastatic lesions; however, metastatic breast carcinoma must be included in the differential diagnosis of tumors of that site in women. We describe a 54-year-old woman who presented with a lesion of the floor of the mouth that histologically resembled polymorphous low-grade adenocarcinoma of the minor salivary glands, which was eventually established to represent metastatic lobular breast carcinoma. The final diagnosis was based on comparison with a primary tumor resected 13 years earlier and immunohistochemical reactivity with antibodies to steroid receptors. Relevant aspects of lobular breast carcinoma, polymorphous low-grade adenocarcinoma, and metastatic oral cavity lesions are discussed.- - - - - - - - - - ranking = 1keywords = floor, mouth (Clic here for more details about this article) |
2/11. Fine-needle aspiration cytology of a primary ectopic meningioma.Meningiomas are benign tumors derived from arachnoid cells. Most commonly an intracranial lesion, meningiomas may be found extracranially in various anatomic sites. A 23-yr-old white female presented with left-sided palpable mass located submucosally in the floor of the mouth. CT scan revealed no evidence of mass elsewhere in the head and neck region. Fine-needle aspiration cytology (FNAC) showed loose and cohesive cellular fragments with lobular growth pattern and uniform round or ovoid cells. The diagnosis of low-grade salivary gland neoplasm, not further classified, was made. The tumor was locally excised. The differential diagnoses of an extracranial meningioma and pleomorphic adenoma were discussed at the frozen section. Based on light microscopic, immunohistochemical, and electron microscopic (EM) findings, the final diagnosis of an ectopic meningioma was rendered. Ectopic meningiomas may pose a diagnostic challenge to clinicians and cytopathologists. It is easily forgotten in the list of differential diagnosis at an ectopic site. Primary ectopic meningioma in a region containing salivary gland(s) may mimic benign and low-grade malignant salivary gland tumors in FNAC.- - - - - - - - - - ranking = 1keywords = floor, mouth (Clic here for more details about this article) |
3/11. An unusual buccal adenoma with extensive squamous metaplasia and cyst formation.Salivary gland tumors are the second most common neoplasm of the mouth following squamous cell carcinoma, and account for a significant proportion of oral tumors. We report a case of an unusual adenoma that presented as a solitary intraoral buccal mass in a 28-year-old male patient. The tumor was intrepreted as an unusual pleomorphic adenoma because of the absence of connective tissue changes and presence of metaplastic epithelial change which is an occasional finding of such tumors. Moreover, the presence of cystic structures with papillary infoldings filled with some crystals and pearl-like keratinized material were also salient features.- - - - - - - - - - ranking = 0.31647033893407keywords = mouth (Clic here for more details about this article) |
4/11. Sialolipoma of the floor of the mouth: a case report.Intra-oral lipoma is a well-known entity, but lipomatous tumors including salivary gland tissue containing clustered or peripherally located ducts and acinar cells are uncommon. They are a newly recognized entity of salivary gland lipoma, designated sialolipoma. We describe a case of sialolipoma arising in the floor of the mouth presenting with apparently normal salivary gland tissue, as demonstrated by both histologic and immunohistochemical findings, in a 67-year-old female. Complete surgical removal of the tumor with preservation of the sublingual gland was implemented after a careful examination confirming that the lesion did not originate from the sublingual gland.- - - - - - - - - - ranking = 5keywords = floor, mouth (Clic here for more details about this article) |
5/11. An unusual case of floor of mouth swelling: case report, differential diagnosis and a review of the literature.The oral cavity is an uncommon site for a true lipoma. A distinct histological variant is the spindle cell lipoma. This is a rare oral lesion. A case of an intra-oral spindle cell lipoma in a 55-year-old female is reported, a differential diagnosis is presented and the histopathology is discussed. CLINICAL RELEVANCE: An oral swelling is a common presenting complaint and requires further investigation.- - - - - - - - - - ranking = 4keywords = floor, mouth (Clic here for more details about this article) |
6/11. Therapeutic experience of recurrent myoepithelial carcinoma by superselective intra-arterial chemotherapy infused high-dose CDDP.Myoepithelial carcinoma is one of several new entities added to the updated classification of salivary gland tumors by the WHO in 1991. This tumor most frequently occurs in parotid gland. This is the first report presenting the tumor in floor of the mouth. It is a rare and prognostic poor cancer. Especially, there was not good therapy for recurrent cases. We treated the patient with repeated recurrences three times and presented in bilateral parapharyngeal space to skullbase in this time. We targeted function preservation and complete cure. In order to accomplish the both objections he received the superselective intra-arterial chemotherapy infused high-dose CDDP with radiation. We confirmed tumor free in FDG-PET in 2 months after the treatment. Now, we cannot detect any recurrence in 7 months after the treatment and he can eat anything and communicate anybody as before treated. We should follow-up him carefully.- - - - - - - - - - ranking = 1keywords = floor, mouth (Clic here for more details about this article) |
7/11. Clear cell carcinoma arising from pleomorphic adenoma of a minor salivary gland: Report of a case with fine needle aspiration, histologic and immunohistochemical findings.BACKGROUND: Malignant changes in pleomorphic adenoma (PA) of the salivary gland (carcinoma ex pleomorphic adenoma) are not common. Clear cell carcinoma is a rare form of salivary gland tumor and involves mostly minor salivary glands, especially those of the palate. Only 3 cases of clear cell carcinoma arising in PA have been reported, 2 in submandibular glands and 1 in a minor salivary gland of the palate. CASE : A 53-year-old man presented with an enlarged mass on the left side of the palate. He had a history of palate mass about 30 years earlier; it was excised and reported as PA. Since then the tumor had recurred twice in the same place; it had been excised and was diagnosed as PA again. A few years later the mass showed rapid growth over a few months. Fine needle aspiration of the mass showed epithelial clusters with bland nuclear features and myxohyaline material typical of PA. Also noted were large and small papillary, trabecular and well-circumscribed clusters of neoplastic cells with a moderate amount offoamy, vacuolated cytoplasm with distinct borders. Glandlike and acinar structures with hyaline globule material resembling cannonballs were also noted. The cytology was suspicious for malignancy. Incisional biopsy was reported as PA. Due to the suspicion of malignancy, the whole mass was excised up to the floor of the orbit. The final diagnosis was clear cell carcinoma expleomorphic adenoma. CONCLUSION: Due to nonspecific cytologic findings in clear cell carcinoma and a mixture of elements of PA in this case, we did not consider clear cell carcinoma as the malignant component.- - - - - - - - - - ranking = 0.68352966106593keywords = floor (Clic here for more details about this article) |
8/11. adenocarcinoma of the sublingual gland.Primary adenocarcinoma arising in the sublingual gland is very rare. In this report, we have described the details of a case of adenocarcinoma of the sublingual gland. A 27-year-old Japanese male was referred to our department with a swelling of the floor of the mouth on the right side. The patient underwent a wide resection of the lesion and dissection of the right upper neck. Twelve months after his primary surgery, he was readmitted to hospital because of a metastasis in the lower lobe of the right lung and a right lower lobectomy was performed. He has undergone periodical controls for 3 years. No sign of recurrence or metastasis has been observed.- - - - - - - - - - ranking = 1keywords = floor, mouth (Clic here for more details about this article) |
9/11. Plasmacytoid myoepithelioma of a minor salivary gland.Plasmacytoid myoepitheliomas are rare salivary gland neoplasms that probably represent a variant of the pleomorphic adenoma. They appear to occur more frequently in the minor salivary glands of the mouth. The mean average age at time of diagnosis of intraoral lesions is 18.8 years. Cytologic pleomorphism is a frequent histologic feature, which has led to a questionable diagnosis of malignancy in five out of ten cases. Caution is advocated in the evaluation of a salivary gland neoplasm with such features, and confusion with primary squamous cell or undifferentiated carcinoma of the salivary glands should be avoided. patients who have cytologically pleomorphic lesions should be assessed for evidence of metastases. Rapid growth, neurologic evidence of sensory or motor dysfunction, and bone invasion should be regarded as ominous clinical parameters. Therapy should be directed toward complete surgical extirpation.- - - - - - - - - - ranking = 0.31647033893407keywords = mouth (Clic here for more details about this article) |
10/11. Intraoral multifocal adult rhabdomyoma. Report of a case and review of the literature.adult rhabdomyomas are uncommon, benign neoplasms of the head and neck region. They are usually solitary, but may rarely be multifocal. We report the clinical and morphologic features of a multifocal adult rhabdomyoma apparently present in the floor of the mouth of an elderly woman for 20 years. At the time of exploratory surgery, the surgeon believed there was diffuse multinodular enlargement of both sublingual glands. The differential diagnosis of a biopsy specimen that was taken for frozen section included salivary gland oncocytosis, a reactive process. On examination of permanent sections, however, the lesion was found to be a multifocal rhabdomyoma. No evidence of salivary gland tissue was found. Ultrastructural study demonstrated the characteristic attempts by this tumor to recapitulate its origin from skeletal muscle by the formation of abnormal contractile elements.- - - - - - - - - - ranking = 1keywords = floor, mouth (Clic here for more details about this article) |
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