Cases reported "Sarcoidosis"

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11/38. Subretinal neovascularisation and snow banking in a case of sarcoidosis: case report.

    A 49-year-old Japanese man presented with chronic granulomatous uveitis in his left eye. Later he developed macular subretinal neovascularisation. The chest x-ray showed bilateral hilar lymphadenopathy. bronchoscopy and gallium-67 scanning were positive, PPD skin test negative, and serum angiotensin converting enzyme (ACE) levels increased. ophthalmoscopy and fluorescein angiography of the left eye showed perivasculitis, retinochoroidal exudates, snow banking, and vitreous opacity. On these findings, the diagnosis of sarcoidosis was made. Treatment was based on topical corticosteroids, mydriatics, beta blockers, and oral carbonic anhydrase inhibitors. After 15 months the visual acuity decreased in the left eye, and a neovascular membrane was observed in the macula. fluorescein angiography confirmed subretinal neovascularisation. Almost two years later the patient still has the neovascular membrane in his left eye.
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12/38. Primary acute pulmonary cavitation in asymptomatic sarcoidosis.

    sarcoidosis has a large variety of chest x-ray manifestations, but primary acute cavitation is very rare. We report a case of cavitary sarcoidosis occurring in an asymptomatic 25 year-old white patient. The diagnosis was established from chest x-ray, transbronchial biopsy specimen, bronchoalveolar lavage and gallium 67 scan. The peculiarities of this case are: 1) the presence of hilar adenopathy; 2) the cavitation occurred during the decreased activity of the disease; 3) the resolution of cavity without therapy. We suggest asymptomatic sarcoidosis should be considered in the differential diagnosis of pulmonary cavitation.
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13/38. Probable myeloblastic leukemoid reaction with disseminated sarcoidosis.

    A 55-year-old woman had progressive weakness, weight loss, night sweats, fever, right-sided facial weakness, and hepatomegaly. Reticulonodular infiltrates were seen on chest x-ray film and a central filling defect was noted on liver scan. Study of the peripheral blood was noted on liver scan. Study of the peripheral blood revealed pancytopenia and myeloblasts. The bone marrow was not markedly hypercellular but contained noncaseating granulomas and myeloblasts. The patient's condition deteriorated and she died on the 22nd hospital day. autopsy disclosed disseminated sarcoidosis but no evidence of leukemic infiltrates. Although concomitant "smoldering" acute leukemia cannot be ruled out, the findings in this patient can be best explained on the basis of a myeloblastic leukemoid reaction accompanying sarcoidosis.
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14/38. sarcoidosis diagnosed in a patient with known hiv infection.

    A 29-year-old black man with hiv infection had an abnormal chest x-ray film with bilateral hilar adenopathy. sarcoidosis was suspected, but a thorough and comprehensive evaluation was completed to differentiate the multiple infectious and noninfectious causes of these findings. biopsy of a hilar node and pulmonary tissue revealed sarcoidosis.
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15/38. Neurosarcoidosis: evaluation using computed tomography and magnetic resonance imaging.

    Two patients with unusual central nervous system sarcoid were investigated using computed tomography and magnetic resonance imaging, as well as other x-ray studies. A patient with intramedullary involvement of the spinal cord as well as nerve root involvement was examined. Follow-up examination after treatment with steroids showed a return to normal. The second patient had optic nerve involvement as well as two intracranial parenchymal lesions and granulomatous arachnoiditis. In this patient magnetic resonance imaging offered no advantages over computed tomography in the orbit but was significantly more accurate intracranially.
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16/38. sarcoidosis presenting with stroke.

    A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar and mediastinal lymphadenopathy and multiple opacities in the lung fields. serum angiotensin converting enzyme concentration was raised, and a kveim test was positive for sarcoidosis. Despite clear pathologic reports of cerebral vasculitis in neurosarcoidosis, the occurrence of stroke is extremely rare.
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17/38. Disseminated sarcoidosis.

    A patient with sarcoidosis manifested by skeletal and cutaneous involvement had a normal chest x-ray and gallium scan of the lungs. The absence of pulmonic disease in spite of the extrapulmonic manifestations of sarcoidosis is rare. A normal chest x-ray does not exclude the diagnosis of sarcoidosis.
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18/38. sarcoidosis in hypersensitivity pneumonitis.

    An abnormal chest x-ray film showing hilar adenopathy, diffuse interstitial pulmonary infiltrations, or both, combined with a tissue biopsy revealing noncaseating granuloma, are suggestive of sarcoidosis; however, non-caseating granuloma may also be found in other forms of pulmonary disease. Immunologic and environmental evaluation of three patients with the diagnosis of sarcoidosis made by the above criteria, revealed hypersensitivity pneumonitis in all. Since therapeutic considerations in these two diseases are different (avoidance being the mainstay in hypersensitivity pneumonitis), all methods to ensure a correct diagnosis should be employed.
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19/38. sarcoidosis with multiple calcification.

    sarcoidosis, having a twenty-nine years of clinical course, associated with multiple calcified deposits in neck, mediastinum, liver, spleen, kidney, abdominal lymphnodes and lung was reported. Calcified opacity, which was firstly detected during initial two years on plain chest and abdominal x-ray films, increased in calcified mass insidiously. Though, the examination on this admission failed to reveal pathogenesis of multiple calcification, immunological derangement seemed to initiate and promote the calcification.
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20/38. sarcoidosis versus foreign-body granulomas.

    A 42-year-old man developed a papulonodular exanthema 10 years following an injury from a shell explosion. The differential diagnosis between sarcoid-like, foreign-body granulomas and Boeck's sarcoid was inconclusive by histology, but x-ray spectroanalytic examination revealed silicon particles within the epitheloid cell granulomas.
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