Cases reported "Sarcoma, Kaposi"

Filter by keywords:



Filtering documents. Please wait...

1/63. Human herpes-virus 8 seropositive patient with skin and graft Kaposi's sarcoma after lung transplantation.

    Kaposi's sarcoma (KS) has been reported after solid organ transplantation mostly in recipients of renal, liver, heart, and bone allografts. We describe the first case of a patient with lung transplantation who developed KS of the skin, but also of the lung graft. The tumors were localized to places of previous trauma, implying the involvement of a Koebner phenomenon. Moreover, a polymerase chain reaction assay revealed the presence of dna sequences of herpesvirus 8 (HHV-8) on tissue of the cutaneous KS. Serological tests showed HHV-8 seronegativity of the graft donor and HHV-8 seropositivity of the patient before lung transplantation suggesting that the latter was already infected before the surgery and that immunosuppression resulted in the development of KS. This case report raises the question of the prevalence of HHV-8 in candidates for transplantation and organ donors, and of the value of an antiviral prophylaxis to lower the risk of KS.
- - - - - - - - - -
ranking = 1
keywords = bone
(Clic here for more details about this article)

2/63. Bone involvement in a case of Kaposi sarcoma.

    BACKGROUND: Extracutaneous involvement is rare in the classical form of Kaposi sarcoma (KS). observation: We report a case of bone involvement revealed by bone pain. Magnetic resonance (MR) images demonstrated the local invasion of bone from cutaneous lesions. Bone biopsy confirmed bone involvement. The patient was treated with vindesine. Bone pain progressively disappeared. CONCLUSION: Bone involvement has rarely been reported in classical KS though 4.5% of the patients were affected when it was systematically sought. Treatment of symptomatic lesions requires radiotherapy or chemotherapy.
- - - - - - - - - -
ranking = 4
keywords = bone
(Clic here for more details about this article)

3/63. Kaposi's sarcoma in bone: a case report with unusual radiographic findings and an abnormal radioisotope scan.

    The authors present a case report of Kaposi's sarcoma involving the bones of the forearm, wrist, and hand. Typical features of rarefaction, osteoporosis, cysts, and cortical erosions were present. Rarely seen changes of a bubbly expansion of the lesions and periosteal reaction were also present. This is the first radioisotope bone scan reported in Kaposi's sarcoma to the author's knowledge. The literature about osseous manifestations of Kaposi's sarcoma is reviewed.
- - - - - - - - - -
ranking = 6
keywords = bone
(Clic here for more details about this article)

4/63. Coexistent gastric MALT lymphoma and Kaposi sarcoma in an hiv positive patient.

    A 47 year old hiv positive male presented with haematemesis and epigastric pain. A gastrectomy was performed for intractable bleeding. The cause of the haematemesis proved to be a Kaposi sarcoma of the stomach which had resulted in mucosal ulceration. Several other smaller foci of Kaposi sarcoma were also present. Coexistent with the Kaposi sarcoma was a dense lymphoid infiltrate with lymphoid follicles and reactive germinal centres. Centrocyte-like cells caused marked effacement and destruction of gastric glands with the formation of lymphoepithelial lesions, typical of a MALT lymphoma. These cells were of B cell lineage and some expressed the hiv antigen, p24. Follicular dendritic cells and macrophages within germinal centres were also p24 positive. immunohistochemistry and in situ hybridisation did not detect Epstein-Barr virus. Although helicobacter pylori was not identified by light microscopy in the sections sampled, this does not preclude its possible role, with other cofactors such as hiv, in the causation of the MALT lymphoma.
- - - - - - - - - -
ranking = 43.119136938542
keywords = macrophage
(Clic here for more details about this article)

5/63. Bacillary angiomatosis affecting the oral cavity. Report of two cases and review.

    Bacillary angiomatosis (BA) is an infectious disease characterized by proliferative vascular lesions; it mainly affects hiv-positive patients. Multiple cutaneous nodular lesions together with fever, chills, malaise, anorexia, vomiting and headache are the most important clinical manifestations. It may also involve the heart, liver, spleen, bones, lung, muscles, lymph nodes, central nervous system and other organs. erythromycin, 500 mg four times a day, is the drug of choice. The importance of this lesion lies in its clinical and histological similarity with other diseases. Cutaneous and oral lesions of BA clinically resemble Kaposi's sarcoma (KS). Histopathologically, BA may be confused with angiosarcoma, pyogenic granuloma and epithelioid hemangioma. We report two hiv-positive men with BA lesions in the oral mucosa. diagnosis was confirmed by biopsy and Warthin-Starry silver staining.
- - - - - - - - - -
ranking = 1
keywords = bone
(Clic here for more details about this article)

6/63. Classical Kaposi's sarcoma involving bone.

    The clinical course of classical endemic Kaposi's sarcoma is indolent and bone involvement is rare unless via direct tumour extension. A case is presented in which isolated bone involvement occurred in the absence of significant overlying skin disease.
- - - - - - - - - -
ranking = 6
keywords = bone
(Clic here for more details about this article)

7/63. Nonmalignant disease associated with human herpesvirus 8 reactivation in patients who have undergone autologous peripheral blood stem cell transplantation.

    fever, cutaneous rash, and hepatitis-for which an infectious cause was suspected-developed in an Italian patient with non-Hodgkin lymphoma after autologous peripheral blood stem cell (PBSC) transplantation. polymerase chain reaction (PCR) with degenerate primers for the highly conserved dna polymerase gene of herpesviruses detected herpesvirus sequences 100% identical to human herpesvirus-8 (HHV-8) in serial cell-free serum samples, collected immediately before or concomitant with the occurrence of clinical symptoms; no other common infections were documented. The presence of the HHV-8 genome (clade C) was confirmed by PCR with HHV-8-specific primers for orf 26 and orf-K1. HHV-8 viremia was undetectable either before transplantation or when the patient was clinically asymptomatic. Semiquantitative PCR analysis showed variations of the viral load correlating with the clinical status. Anti-HHV-8 antibodies were detected before and after transplantation by an immunofluorescence assay for lytic antigens. Active HHV-8 infection may be associated with nonmalignant illness after PBSC/bone marrow transplantation.
- - - - - - - - - -
ranking = 1
keywords = bone
(Clic here for more details about this article)

8/63. Kaposi's sarcoma-like lesions and other nodules as cutaneous involvement in AIDS-related visceral leishmaniasis.

    A 40-year-old human immunodeficiency virus (hiv)-positive man had three relapses of visceral leishmaniasis (VL). In the third he developed nodular skin lesions of three types, some reminiscent of Kaposi's sarcoma. biopsy of each type disclosed abundant dermal macrophages with a huge number of intracellular and extracellular Leishman-Donovan bodies. Rapid improvement of lesions was achieved after antiparasitic treatment. AIDS leads to atypical forms of leishmaniasis. Leishmania has been detected both in normal and pathological skin of these patients due to dissemination during VL. It is suspected that a considerable proportion of the population may be infected in endemic areas, Leishmania being opportunistic in immunosuppressed individuals. It is important to recognize the range of lesions that may occur in patients with hiv and VL, many of which are non-specific and may cause diagnostic difficulty.
- - - - - - - - - -
ranking = 43.119136938542
keywords = macrophage
(Clic here for more details about this article)

9/63. Mycobacterial spindle cell pseudotumor of the appendix vermiformis in a patient with aids.

    Mycobacterial pseudotumor (MP) is a rare pathologic presentation of both mycobacterium tuberculosis and non-tuberculous mycobacterial disease, hitherto reported to occur only in immunosuppressed patients with or without human immunodeficiency virus infection. This lesion shares close pathologic resemblance to certain mesenchymal neoplasms, particularly Kaposi's sarcoma (KS), from which it must be properly differentiated due to distinct prognosis and therapy. We report a case of MP obliterating the lumen of the appendix vermiformis in a 34-year-old patient who died of complications of AIDS at our hospital in Rio de Janeiro. A total of 24 cases of MP (including our patient) have been described in the literature. MP has been found especially in lymph nodes, but extranodal lesions have been described in the skin, spleen, lung, bone marrow, brain and, in our patient, the appendix vermiformis. We offer a review of the other 23 published case reports of MP in both hiv-infected and uninfected patients and discuss the pathologic features that differentiate MP from KS.
- - - - - - - - - -
ranking = 1
keywords = bone
(Clic here for more details about this article)

10/63. Localization of retrovirus in the central nervous system of a patient co-infected with HTLV-1 and hiv with HAM/TSP and hiv-associated dementia.

    persons co-infected with HTLV-1 and hiv are at increased risk for neurologic disease. These patients may develop HAM/TSP and/or hiv-associated dementia. In this study, we localized cells infected with retrovirus in the central nervous system (CNS) of a patient with both HAM/TSP and hiv-associated dementia. HTLV-1 was localized to astrocytes and hiv to macrophage/microglia. There was no co-infection of a single cell phenotype in this patient. These data suggest that mechanisms other than co-infection of the same CNS cell may play a role in the development of neurologic disease in patients dual infected with HTLV-1 and hiv.
- - - - - - - - - -
ranking = 43.119136938542
keywords = macrophage
(Clic here for more details about this article)
| Next ->


Leave a message about 'Sarcoma, Kaposi'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.