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1/2. Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections.

    Five patients with campylobacter fetus(previously called "Vibrio fetus") bacteremia are presented with enteric symptoms in four patients, a self-limited course in three, and with possible nosocomial infection in one patient who had disseminated malignancy. The clinical syndromes of 91 bacteremic patients with campylobacteriosis and C. fetus taxonomy and pathogenicity are reviewed. Studies of potential pathogenic mechanisms in enteric infections failed to reveal the production of either heat-stable or heat-labile, cholera-like enterotoxin, cytotoxicity or invasiveness. In comparison with different species of vibrio infections, C. fetus appears to produce disease by a different mechanism, one which involves a bloodstream infection, perhaps following penetration through the intestinal mucosa as has been demonstrated experimentally with salmonellae and yersinia. Such a pattern is consistent with the clinical pattern of C. fetus infections and the experimental studies reported herein.
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ranking = 1
keywords = yersinia
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2/2. Splenic abscess as a complication of septic yersinia: CT evaluation.

    yersinia enterocolitica (YE) frequently causes gastrointestinal illness, but is rarely a cause of systemic infection. The complications of septic YE include a wide variety of extraintestinal manifestations, with a 34-50% mortality rate. We present a patient with septic YE complicated by a splenic abscess. The clinical presentation was nonspecific, and the diagnosis of splenic abscess was made by computed tomography (CT). Because of the nonspecific clinical presentation and the wide range of extraintestinal manifestations of septic YE, CT can prove helpful in the diagnosis and management of these patients.
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ranking = 4
keywords = yersinia
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