1/10. amiodarone-induced concomitant first and second degree sinoatrial block.The occurrence of concomitant first and second degree sinoatrial block due to chronic amiodarone treatment in 1 patient with moderate mitral valve stenosis is described. Discontinuation of amiodarone resulted in the disappearance of such a sinoatrial conduction disturbance.- - - - - - - - - - ranking = 1keywords = disturbance (Clic here for more details about this article) |
2/10. trichloroethylene and cardiac toxicity: report of two consecutive cases.About two consecutive cases of acute intoxication by trichloroethylene, the authors want to point out the possible occurrence of serious disturbances in cardiac conduction which are less frequently described in the literature than disturbances in myocardial excitability.- - - - - - - - - - ranking = 2keywords = disturbance (Clic here for more details about this article) |
3/10. Sinoatrial and atrioventricular dysfunction associated with the use of guanabenz acetate.guanabenz acetate is an antihypertensive drug that is closely related to clonidine hydrochloride. clonidine is well known to potentiate atrioventricular (AV) node conduction disturbances, but to date that effect has not been attributed to guanabenz. A case of electrocardiographic and electrophysiologic studies in a patient with both sinus and AV node conduction disturbances associated with the use of guanabenz acetate is reported. The sinus cycle length was increased by 50% after guanabenz and the sinus node recovery time was prolonged by 42%. AV block occurred proximal to the His bundle and His-ventricular prolongation of 42% also occurred. This drug should be used cautiously in patients with evidence of sinus or AV node dysfunction.- - - - - - - - - - ranking = 2keywords = disturbance (Clic here for more details about this article) |
4/10. Corticosteroids in the management of sinoatrial block.This report presented our experience in the treatment of sinoatrial (S-A) conduction disturbances with corticosteroids. Three patients with intermittent second-degree S-A block who failed to respond to atropine and isoproterenol were treated with prednisone for 6-17 weeks. Sustained improvement in S-A conduction following prednisone administration was confirmed by repeated Holter monitoring on and off therapy. Two patients eventually regained permanent sinus rhythm, while therapy led to marked diminution in S-A block in the 3rd patient. The possible mechanisms by which steroids may improve S-A conduction are discussed. Our observation is based on a small case series, each patient serving as his own control, and as such constitutes an indication for further confirmatory studies.- - - - - - - - - - ranking = 1keywords = disturbance (Clic here for more details about this article) |
5/10. sinoatrial block induced by oral diltiazem.A 58-year-old man with variant angina who had no history suggestive of sinus node dysfunction experienced palpitation with pulse deficit after 8 days of diltiazem treatment, 240 mg per day. Electrocardiogram (ECG) revealed frequent occurrence of sinoatrial block. After discontinuation of diltiazem, an ambulatory ECG demonstrated gradual reduction of the occurrence of sinoatrial block, and no recurrence 8 hours after the last dose of the drug. One should note that diltiazem induces not only sinus node suppression and atrioventricular conduction disturbance, but also sinoatrial block.- - - - - - - - - - ranking = 1keywords = disturbance (Clic here for more details about this article) |
6/10. Atrioventricular and sinoatrial block in thyrotoxic crisis.A 55 year old woman in thyrotoxic crisis developed atrial fibrillation, atrioventricular block, and sinoatrial block in rapid succession. All of these abnormalities resolved completely after antithyroid treatment. This course of events illustrates the profound effect of thyroid hormones on cardiac function. In view of the potential aggravation of atrioventricular conduction disturbance by beta adrenergic blocking agents, thyrotoxic patients should be carefully screened for electrocardiographic evidence of conduction disturbance before the administration of such drugs.- - - - - - - - - - ranking = 2keywords = disturbance (Clic here for more details about this article) |
7/10. Cardiac conduction disturbances during carbamazepine therapy.3 cases of carbamazepine (CBZ)-induced Stokes-Adams attacks caused by intermittent total atrioventricular block, sino-atrial block with junctional escapade-rhytm and intermittent asystolia are reported. After cessation of CBZ treatment, the cardiac conduction disturbances disappeared. In 2 of the patients, the diagnosis was confirmed by resumption of treatment with CBZ after insertion of a demand pacemaker. If syncopes or changes in seizure-type occur in patients treated with CBZ, evaluation of cardiac conduction is recommended. Furthermore, it is recommended that cardiac function is evaluated before CBZ-treatment, especially in elderly patients.- - - - - - - - - - ranking = 5keywords = disturbance (Clic here for more details about this article) |
8/10. Alternation of sinoatrial block and left bundle branch block.A case of alternating second degree sinoatrial block and left bundle branch block is described. Electrophysiologic evaluation of this patient revealed impaired sinoatrial, atrioventricular and intraventricular conduction (panconductional defect). Alternation of intraventricular conduction disturbances with sinoatrial block can be explained by the tachycardia-dependent (phase-3-dependent) occurrence of the left bundle branch block.- - - - - - - - - - ranking = 1keywords = disturbance (Clic here for more details about this article) |
9/10. Symptomatic sinus arrest in a young girl.Sinus node dysfunction, previously unreported in girls, occurred in a 13-year-old girl who required permanent pacemaker implantation because of recurrent syncopal attacks. In addition to periodic sinus arrest, the presence of significant atrioventricular conduction disturbance was also documented. Although she had had a persistent ductus arteriosus divided at an earlier age, the disturbance of rhythm and conduction cannot be ascribed to a congenitial or haemodynamic abnormality. An acquired origin can only be postulated.- - - - - - - - - - ranking = 2keywords = disturbance (Clic here for more details about this article) |
10/10. Evidence for sinoatrial blockade associated with high dose cytarabine therapy.cytarabine therapy is rarely complicated by cardiotoxicity. The present report describes the clinical course of a 35-year-old female patient with acute myelogenous leukemia in complete remission, who developed sinus bradycardia while on high dose cytarabine as a consolidation therapy. The electrocardiographic findings suggested that bradycardia was most probably the result of sinoatrial blockade. The available information regarding a possible association of cytarabine with disturbances of cardiac rhythm is reviewed.- - - - - - - - - - ranking = 1keywords = disturbance (Clic here for more details about this article) |
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