Cases reported "Skull Neoplasms"

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11/218. Multimodality management of a case of primary osteogenic sarcoma of the zygoma.

    Craniofacial osteogenic sarcomas are rare primary malignant bone tumors and very few cases involving zygomatic bone were reported in literature. We present our experience of multimodality management of a case of primary osteogenic sarcoma of zygoma. Wide radical excision of the tumor including the parotid gland was done followed by three cycles of adjuvant chemotherapy and fifty Gy of external radiotherapy. The patient is disease-free at two years follow-up. Till 1970s, craniofacial osteogenic sarcomas were managed mainly by radical surgery with a high local failure rate. With the advances made in the field of radiotherapy and chemotherapy, multimodality therapy is playing a major role in the treatment of these aggressive tumors with better overall and disease-free survival.
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ranking = 1
keywords = sarcoma
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12/218. Sinonasal teratocarcinosarcoma: ultrastructural and immunohistochemical evidence of neuroectodermal origin.

    The authors report a case of sinonasal teratocarcinosarcoma in a 37-year-old man, which was located in the anterior skull base and extended to the right nasal cavity and paranasal sinuses. The tumor was surgically resected twice, but it could not be removed completely. Microscopically, it was mainly composed of primitive cell nests within a moderately cellular stroma. The components of squamous cell epithelia with focal teratoid appearance and adenocarcinomatous differentiation were observed. There were many rhabdomyoblasts scattered in the nests and stroma. Ultrastructurally, the primitive cells had many neural processes with parallel microtubules, resembling olfactory neuroblastoma. Rhabdomyoblasts showed various degrees of skeletal muscle differentiation. Some of the stromal spindle cells had actin filaments with dense patches and dense core granules. Immunohistochemically, the primitive cells were positive for epithelial markers, neuron-specific enolase, synaptophysin, and myogenic regulatory proteins. The rhabdomyoblasts showed immunoreactivity for myoid markers, cytokeratin, epithelial membrane antigen, and synaptophysin. Most of the stromal spindle cells were positive for smooth muscle actin, neuron-specific enolase and synaptophysin. The immunohistochemical and ultrastructural findings suggest that primitive cells had the most primitive phenotype of placodes, and support the possibility that sinonasal teratocarcinosarcoma is essentially a neuroectodermal tumor with divergent differentiation.
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ranking = 0.85714285714286
keywords = sarcoma
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13/218. Osteosarcomatosis involving craniofacial bones presenting with cranial nerve palsies.

    Osteosarcomatosis (also known as multifocal osteosarcoma or multiple sclerotic osteosarcoma) is a rare condition, characterized by multiple skeletal lesions at initial presentation. We describe a case of osteosarcomatosis involving craniofacial bones presenting with cranial nerve palsies. In addition, a brief review of the literature is given, with a discussion of this highly aggressive form of osteosarcoma.
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ranking = 1.2857142857143
keywords = sarcoma
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14/218. Ewing's sarcoma of the facial zygomatic area bones in a young child: a case presentation.

    We present the case of a young patient with Ewing's sarcoma of the facial zygomatic area bones. This type of tumor in a very young child is a rare event and poses significant diagnostic and therapeutic challenges for the attending physician. In this case, the diagnosis was made by a computed tomography scan with subsequent histological confirmation. The differential diagnoses and therapeutic options are discussed.
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ranking = 0.71428571428571
keywords = sarcoma
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15/218. Primary Ewing's sarcoma of the greater wing of the sphenoid bone.

    Primary Ewing's sarcoma is an uncommon lethal tumour of the long bones and pelvic girdle mainly affecting children and young adults. An origin in the cranial bones is extremely rare. We report a unique case of primary involvement of the greater wing of sphenoid bone in a 16-year-old patient. Aggressive management using microsurgical resection, radiotherapy and chemotherapy was curative. Localized, primary Ewing's sarcoma of the cranial bones should be considered as a distinct clinicopathological entity with an extremely low rate of dural penetration and metastases, and with a relatively better prognosis as compared with those of long bones and pelvic girdle. In neurosurgical practice, primary Ewing's sarcoma of the cranial bones requires early aggressive management to achieve adequate long-term prognosis and cure.
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ranking = 1
keywords = sarcoma
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16/218. Primary petrous bone Ewing's sarcoma.

    A case of primary Ewing's sarcoma involving a large portion of the petrous temporal bone in an eighteen month old child is reported. The lesion was treated by radical surgery and adjuvant chemotherapy and radiotherapy. An extremely rare age of presentation, an unusual location and an excellent response to treatment are the highlights of this case.
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ranking = 0.71428571428571
keywords = sarcoma
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17/218. osteosarcoma of the sella.

    Primary osteosarcoma of the skull is rare. osteosarcoma arising from the sellar region is extremely uncommon. The case of a 38-year-old man with osteosarcoma of the sella is described, and the literature is reviewed. The patient was treated with surgery followed by aggressive chemotherapy and radiotherapy. Currently he is in remission at 12 months.
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ranking = 1
keywords = sarcoma
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18/218. Fibromyxoma of the petrous apex.

    The common petroclival bony tumors are chordoma and chondrosarcoma. myxoma of the bone occurs only in the facial bones, and it has not been reported in skull bones. The computed tomographic scanning, magnetic resonance imaging and intraoperative characteristics of a case of fibromyxoma of the petrous bone in a 14-year-old girl are described.
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ranking = 0.14285714285714
keywords = sarcoma
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19/218. Primary cranial Ewing's sarcoma.

    Primary Ewing's sarcoma of the cranium is extremely rare, with only 17 cases reported so far. We describe a further case with involvement of the frontotemporal region and the orbit. The patient, an adult male, was admitted with headache and papilloedema, and later developed localised swelling and proptosis. He was treated with surgery, radiotherapy and chemotherapy, and was free from metastases during a follow-up of 14 months. The prognosis of Ewing's sarcoma is improving with radiotherapy and chemotherapy. Further cases are needed to study the biological behaviour of primary cranial Ewing's sarcoma.
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ranking = 1
keywords = sarcoma
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20/218. Periosteal osteosarcoma of the cranium.

    We report a case of periosteal osteosarcoma arising from the occiput in a 29-year-old woman. To the best of our knowledge, this is the first documented case of periosteal osteosarcoma involving the cranium.
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ranking = 0.85714285714286
keywords = sarcoma
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