Cases reported "Splenomegaly"

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1/6. epiglottis involvement in a visceral leishmaniasis.

    The visceral form of leishmaniasis caused by leishmania infantum is frequently observed in Mediterranean countries, however otorhinolaryngeal involvement has only rarely been reported in the literature. We report here the case of a 23-year-old cameroon man, resident in france since 1991, and presenting with recurrent epistaxis and an epiglottis tumoral lesion. The visceral form of leishmaniasis with hepatosplenomegaly and pancytopenia was diagnosed. culture of the epiglottal lesion revealed L. infantum. Serological test for human immunodeficiency virus was negative and the patient was not on immunosuppressive drugs. Dramatic improvement was observed with antimony.
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keywords = leishmaniasis
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2/6. Visceral leishmaniasis: a difficult diagnosis and unusual causative agent.

    In a young man who had a prolonged fever of unknown origin, hepatosplenomegaly, and progressive pancytopenia, stained smears, blood-agar cultures of bone marrow, and serologic testing for antileishmanial antibodies were negative. Biopsies from liver and bone marrow were uninformative. Visceral leishmaniasis was diagnosed only after splenectomy, when amastigotes were finally cultured from the spleen. The parasite was shown to be an unusual leishmanial parasite, possessing a mixture of intrinsic biochemical and serologic characteristics displayed independently by leishmania tropica and leishmania donovani sensu lato, the latter being the usual cause of visceral leishmaniasis. After splenectomy, parasites were also demonstrated in stained bone marrow aspirate smears. Recovery was uneventful after treatment with antimony for 28 days. Visceral leishmaniasis can be a cause of fever of unknown origin and should be considered in its differential diagnosis in endemic areas.
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ranking = 1.1666666666667
keywords = leishmaniasis
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3/6. CT findings in visceral leishmaniasis mimicking lymphoma.

    A case of visceral leishmaniasis (Kala-Azar) is presented which clinically and on CT examination mimicked lymphoma. The value of the recognition of the previously unreported CT findings of visceral leishmaniasis is discussed.
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keywords = leishmaniasis
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4/6. Kala-azar in afghanistan.

    The first three cases of kala-azar from afghanistan are reported. Two girls (aged 4 and 5 years) and a 5-year-old boy reported from Kabul and Badghis Province with classical features of visceral leishmaniasis. The diagnosis was based on the demonstration of amastigotes in the bone marrow.
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ranking = 0.16666666666667
keywords = leishmaniasis
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5/6. Visceral leishmaniasis after cardiac surgery.

    An English child developed visceral leishmaniasis (kala-azar) after cardiac surgery. Neither he nor his mother had ever been out of the UK, and his disease was probably transmitted by blood transfusion. Kala-azar should be considered in patients with unexplained fever and hepatosplenomegaly, even if there is no history of foreign travel.
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ranking = 0.83333333333333
keywords = leishmaniasis
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6/6. Regression of diffuse intralobular liver fibrosis associated with visceral leishmaniasis.

    Diffuse intralobular fibrosis of the liver is rare in cases of New World visceral leishmaniasis. A patient with this disease from a newly endemic area in the northernmost area of the Brazilian Amazon region was studied. hypertrophy and hyperplasia of the phagocytic mononuclear cell system were observed, with parasitism and Disse's space fibrosis diffusely involving the liver. This description is based on a biopsy carried out after seven days of treatment with Glucantime. Another biopsy performed almost two years later showed no fibrosis, no Kupffer cell hypertrophy and hyperplasia, and no parasitism. The mechanism of fibrosis and regression is discussed.
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ranking = 0.83333333333333
keywords = leishmaniasis
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