Cases reported "Sweat Gland Diseases"

Filter by keywords:



Filtering documents. Please wait...

1/11. Acral erythrodysesthesia syndrome caused by intravenous infusion of docetaxel in breast cancer.

    Docetaxel-induced skin reactions include hypersensitivity, edema, skin toxicity with erythrodysesthesia syndrome, infusion site reactions, alopecia, nail onycholysis, nail pigmentation, photosensitivity, scleroderma, and others, for example, stomatitis and paresthesias. However, of all reported effects, the acral erythrodysesthesia syndrome has only rarely been described in the literature. We report on two female patients with breast cancer who on treatment with docetaxel developed acral erythrodysesthesia syndrome. It presented as bizarrely shaped, burning skin reactions at their hands and feet. histology of skin biopsies revealed microscopic damages to the eccrine sweat glands in both patients. skin patch testing with docetaxel was negative. None of the reports dealing with side effects of docetaxel chemotherapy has described acral erythrodysesthesia syndrome with the histologic features of syringo-squamous metaplasia and eccrine neutrophilic hidradenitis. We propose here that these characteristic histologic features are essential in the differentiation from fixed drug eruption and localized graft-versus-host disease.
- - - - - - - - - -
ranking = 1
keywords = neutrophilic
(Clic here for more details about this article)

2/11. Neutrophilic eccrine hidradenitis in two neutropenic patients.

    Neutrophilic eccrine hidradenitis is an uncommon, self-limited dermatosis with a variable clinical presentation. It seems to be due to chemotherapeutic drugs in most cases. necrosis of the eccrine gland associated with a neutrophilic infiltrate is the histologic hallmark of this disease. We report two additional cases in neutropenic patients with acute myelogenous leukemia in which there was a striking lack of neutrophil infiltration. A new term, drug-associated eccrine hidradenitis, is suggested.
- - - - - - - - - -
ranking = 1681.8529950153
keywords = eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

3/11. Neutrophilic eccrine hidradenitis associated with Hodgkin's disease and chemotherapy. A case report.

    A 44-year-old man with Hodgkin's disease developed fever and erythematous macules and plaques associated with doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. biopsy results demonstrated a neutrophilic infiltrate around sweat glands and degeneration of eccrine glands. These findings are characteristic of neutrophilic eccrine hidradenitis, which, to our knowledge, has previously been reported only in patients with acute myelogenous leukemia who were receiving cytarabine chemotherapy. Neutrophilic eccrine hidradenitis may represent a reaction pattern to chemotherapeutic agents and may not be specific for a particular disease or drug.
- - - - - - - - - -
ranking = 2961.8983363459
keywords = neutrophilic eccrine hidradenitis, eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

4/11. Neutrophilic eccrine hidradenitis. Evidence implicating bleomycin as a causative agent.

    A 13-year-old girl receiving multiple agent chemotherapy for osteosarcoma was found to have neutrophilic eccrine hidradenitis (NEH). This dermatosis is marked histopathologically by necrosis of the eccrine structures with a neutrophilic infiltrate. Clinically, the presentation is variable and the differential diagnosis is extensive. Our patient's clinical picture was unique in that she had hyperpigmented plaques instead of purpuric nodules or erythematous plaques as described previously. Currently, NEH is felt to be a complication of chemotherapy. The most likely causative agent in our patient was bleomycin. physicians should be aware of this entity and its variable clinical presentation.
- - - - - - - - - -
ranking = 2681.75617051
keywords = neutrophilic eccrine hidradenitis, eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

5/11. Neutrophilic eccrine hidradenitis: a case report and review of the literature.

    Neutrophilic eccrine hidradenitis (NEH) is a recently recognized dermatosis occurring in patients receiving chemotherapy for a variety of malignancies. We report the second pediatric case. An 11-year-old boy with non-Hodgkin's lymphoma developed widespread erythematous papulopustules beginning two days after receiving high-dose cytarabine (Ara-C) in preparation for a bone marrow transplant. The lesions spontaneously regressed in two weeks. Histologic examination revealed a neutrophilic infiltrate around and within the eccrine ducts and secretory coils. Bacterial, fungal, and viral cultures were negative. These findings are characteristic of NEH. The condition should be differentiated from infectious dermatoses that may require treatment.
- - - - - - - - - -
ranking = 1401.7108291794
keywords = eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

6/11. Chemotherapy-associated eccrine hidradenitis: neutrophilic eccrine hidradenitis reevaluated: the role of neutrophilic infiltration.

    Two cases of chemotherapy-associated eccrine hidradenitis are presented. Previous cases have been labeled "neutrophilic eccrine hidradenitis" (NEH). Both cases reported herein involve neutropenic patients and are notable for the absence of neutrophils on histologic examination. Oncologists need to be aware of this newly described process, and this rash must be added to the differential diagnosis of the neutropenic oncology patient. The role of neutrophils in this disorder is discussed, and a new term, "chemotherapy-associated eccrine hidradenitis," is suggested for this unusual process.
- - - - - - - - - -
ranking = 9485.7905308476
keywords = neutrophilic eccrine hidradenitis, eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

7/11. Neutrophilic eccrine hidradenitis in the absence of an underlying malignancy.

    Neutrophilic eccrine hidradenitis is an entity previously reported to occur in association with malignancy and chemotherapy. We report a case of clinical and histopathologic findings characteristic of neutrophilic eccrine hidradenitis occurring without apparent underlying disease. In addition, the only medication this patient was taking was acetaminophen. Neutrophilic eccrine hidradenitis appears to represent a reaction pattern without specificity for underlying disease or inciting agent.
- - - - - - - - - -
ranking = 3241.0405021818
keywords = neutrophilic eccrine hidradenitis, eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

8/11. Neutrophilic eccrine hidradenitis in acute myelomonocytic leukemia.

    Neutrophilic eccrine hidradenitis is a rare but distinct dermatosis that has recently been described in adults with acute myelogenous leukemia. We report the first pediatric case in an 11-year-old girl with acute myelomonocytic leukemia who developed this eruption following her first and second course of VAPA-10 induction chemotherapy. skin biopsy revealed selective neutrophilic infiltration around the eccrine coils, which is characteristic of this dermatosis. The clinical and biopsy findings of our patient are presented and compared with the previous three reported cases.
- - - - - - - - - -
ranking = 1401.7108291794
keywords = eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

9/11. Neutrophilic eccrine hidradenitis associated with induction chemotherapy.

    We report three new cases of neutrophilic eccrine hidradenitis associated with induction chemotherapy which resolves two major points. First, because two of our patients had testicular carcinoma; this firmly establishes that NEH is not exclusively seen in patients with acute myelogenous leukemia or Hodgkin's lymphoma as previously reported. Second, because two of our patients did not receive cytarabine which has previously been suspected of being the causative agent, it is apparent that this disorder may be produced by more than one chemotherapeutic agent or combination of agents. The histologic features with a discussion of the spectrum of changes which may be seen are presented.
- - - - - - - - - -
ranking = 2680.75617051
keywords = neutrophilic eccrine hidradenitis, eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)

10/11. Neutrophilic eccrine hidradenitis: a distinctive rash associated with cytarabine therapy and acute leukemia.

    Neutrophilic eccrine hidradenitis (NEH) is a recently described neutrophilic dermatosis associated with acute myelogenous leukemia (AML) and chemotherapy. This disorder is a distinct clinicopathologic entity separate from leukemid reactions and other neutrophilic dermatoses. We describe two cases in which plaques or nodules developed in the second week after initiation of induction chemotherapy for AML. The lesions regressed in 1 week and recurred in one case when induction chemotherapy was given a second time. Histologically, the findings were similar in each case. neutrophils palisaded about and infiltrated the eccrine coil in which necrosis of secretory epithelium was present. Focal mucinous degeneration of the eccrine adipose tissue cuff was the only other significant alteration. No vasculitis was observed. Cultures and histologic preparations for pathogenic organisms were negative. cytarabine was the chemotherapeutic agent used in all three cases. NEH most likely represents either an unusual response caused by cytarabine or a manifestation of AML. Recognition of NEH is important in order to exclude other neutrophilic dermatoses associated with AML, such as sepsis and leukemia cutis, which may appear clinically similar.
- - - - - - - - - -
ranking = 1403.7108291794
keywords = eccrine hidradenitis, neutrophilic
(Clic here for more details about this article)
| Next ->


Leave a message about 'Sweat Gland Diseases'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.