Cases reported "Teratoma"

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1/10. fibrosarcoma associated with a benign cystic teratoma of the ovary.

    OBJECTIVE: A case of ovarian fibrosarcoma associated with a benign cystic teratoma is described. methods: A 32-year-old patient with an ovarian tumor detected by routine gynecological examination was referred to our hospital. In addition to histopathological examination of the resected tumor, immunohistochemical studies as well as a cytogenetic analysis by comparative genomic hybridization were carried out. RESULTS: The 7-cm-sized tumor consisted of two different components: a fibrosarcoma and a benign cystic teratoma. The teratoma contained elements of all three germ layers and lacked any focus of immature teratoma. A fibrosarcoma was immediately connected to the teratoma. The sarcoma cells showed eight mitoses per 10 high-power fields on average and exhibited immunohistochemical reactivity for vimentin only. cytogenetic analysis of the fibrosarcoma using comparative genomic hybridization revealed imbalances of chromosomes 9, 12, and 16. After a 1-year follow-up, there were no signs of tumor recurrence or systemic disease. CONCLUSION: To the authors' knowledge, this is the second report of an association of ovarian fibrosarcoma and benign cystic teratoma, and the first including a cytogenetic analysis.
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ranking = 1
keywords = gynecologic
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2/10. Immature ovarian teratoma with hyponatremia and low antidiuretic hormone level.

    BACKGROUND: Inappropriate antidiuretic hormone secretion syndrome is rare in patients with gynecologic tumors. CASE: A 22-year-old woman presented with inappropriate antidiuretic hormone secretion symptoms during the 2 months preceding the diagnosis of an immature ovarian teratoma. Vasopressin levels in serum and in the urine were very low. Restriction of water intake and surgical removal of the teratoma resulted in the definitive correction of the hyponatremia. This observation suggests that immature teratoma cells can produce a vasopressin-like factor, and the syndrome may be a sign of an ovarian malignancy. CONCLUSION: Pelvic organs should be examined when the more common causes of inappropriate antidiuretic hormone secretion syndrome have been ruled out.
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ranking = 1
keywords = gynecologic
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3/10. Ovarian abscess from salmonella: a case report.

    BACKGROUND: An ovarian site of salmonella bacteremia is rare. The contents of a teratoma may hide the organisms easily. Clinicians should be alert to this possibility when the patient had a teratoma with salmonella infection. CASE: A 19-year-old woman presented with a missed menstrual period. An adnexal mass was found during a routine gynecologic examination. The patient had had gastroenteritis 2 months earlier but did not complain of a gastrointestinal problem at presentation. Exploratory laparotomy was performed for a suspected ovarian tumor. An infective teratoma was considered, but the infection source was unknown until the culture report showed a salmonella infection. CONCLUSION: salmonella infection is a self-limiting, febrile disease and is unlikely to involve organs other than the gut. A nontyphoid ovarian abscess became a rare late complication of acute gastroenteritis. Clinicians should pay special attention to the differential diagnosis of ovarian tumor in patients with a history of salmonella infection, especially those with such ovarian lesions as endometrioma or teratoma and with recent abdominal pain, as noted in this case.
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ranking = 1
keywords = gynecologic
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4/10. Conservative management of chylous ascites after removal of a symptomatic growing retroperitoneal teratoma.

    BACKGROUND: chylous ascites as a postoperative complication of gynecologic surgery is uncommon. Cases usually occur from trauma to the lymphatic system during retroperitoneal dissection. Initial management includes paracentesis with institution of a low-fat, medium-chain triglyceride diet and total parenteral nutrition (TPN). Surgical intervention may be required. CASE: A 19-year-old female patient with a history of an immature teratoma treated with chemotherapy presented with a retroperitoneal mass. Removal of the mass revealed mature teratoma and resulted in chylous ascites formation. Multiple paracenteses were performed in conjunction with dietary modification and TPN. Three months after the patient's surgery, the ascites spontaneously resolved. CONCLUSION: Although surgical intervention is recommended after failure of conservative management, this case demonstrates that damage to the cisterna chyli may spontaneously resolve.
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ranking = 1
keywords = gynecologic
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5/10. Acute pulmonary embolism following laparoscopic ovariectomy: a case report.

    Laparoscopic surgery is usually considered to be less invasive when compared to traditional laparotomy, and is regarded as a relatively low-risk procedure for postoperative complications because of the reduced surgical stress and earlier mobilization. However, we describe a 47-year-old woman who presented with acute respiratory distress, drowsy consciousness, and circulatory collapse shortly after gynecologic laparoscopic ovariectomy for removing an ovarian teratoma at a local hospital. After resuscitation, the patient was transferred to our emergency department. Immediate bedside electrocardiographic and echocardiographic examination results led to acute pulmonary embolism being quickly diagnosed. The patient received subsequent intensive care with smooth course. Although pulmonary embolism is rare after laparoscopic surgery, early detection and quick treatment are important in the management of this life-threatening complication and offer good prognosis. The risk of pulmonary embolism after gynecologic laparoscopic surgery remains unclear. Therefore, the decision to provide prophylaxis is up to the individual physician, and should take into consideration the patient's individual risk factors and comorbidities.
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ranking = 2
keywords = gynecologic
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6/10. Placental site trophoblastic tumor associated with immature ovarian teratoma.

    This paper describes a woman who developed three malignancies within a very short time. Two of these, immature teratoma and placental site trophoblastic tumor, were rare gynecological neoplasms. The third was a breast carcinoma. This is the first report of an association of placental site trophoblastic tumor with a primary germ cell tumor of the ovary.
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ranking = 1
keywords = gynecologic
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7/10. Immunocytochemical evidence of heterogeneous origin of alpha-fetoprotein in immature teratoma of the ovary.

    alpha-Fetoprotein (AFP) has been found to be clinically important in the management of patients with gynecologic malignancies. serum AFP levels are used as tumor markers for ovarian tumors, namely endodermal sinus tumors (EST) and embryonal tumors. In two cases of immature teratoma of the ovary without a yolk sac component, evidence for AFP production was found in a wide variety of cells of both endodermal and ectodermal origin suggesting a heterogeneous origin of AFP. To complement this finding, a summary of the ontology of AFP along with current and potential uses of an antigenically active tumor marker are presented.
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ranking = 1
keywords = gynecologic
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8/10. Management of patients with gynecologic cancer by serum sialic acid determination.

    With an enzymatic technique, serum sialic acid (SA) levels were determined in patients with gynecologic tumors. Since the SA level for healthy females was 57.4 /- 7.3 mg/dl, we set the upper normal limit of this parameter at 72 mg/dl. The SA level became larger in ascending order of uterine myoma, benign ovarian tumor, cervical cancer, corpus cancer, and ovarian cancer. The SA level proved to be significantly higher in cancer patients showing poor prognosis than in those having good prognosis irrespective of the category of therapy and it reflected well the clinical course of cancer patients. In patients who receive a combination therapy and need to be followed up for a long term, complete follow-up is sometimes impossible with tumor-derived markers alone. Even in such cases, the sialic acid level will work as a useful follow-up marker because it is nonspecific to histologic types of cancer.
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ranking = 5
keywords = gynecologic
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9/10. Misdiagnoses in obstetric and gynecologic ultrasound examinations: causes and possible solutions.

    Two small series of cases documenting ultrasound misdiagnoses are presented. The first concerns obstetric ultrasound misdiagnoses originating in the private offices of physicians. The second concerns gynecologic ultrasound misdiagnoses originating in a level II medical center. A dichotomy exists in the use of diagnostic ultrasound examination in the practice of obstetrics and gynecology. The dichotomy is a serious defect in our specialty that needs urgent addressing. The institutional problem can be partially resolved by furnishing the sonographer with the referred patient's history and physical findings. The problem of the ultrasound machine in the office of a private physician is much more complex. It may require government intervention and strict licensing measures for resolution.
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ranking = 5
keywords = gynecologic
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10/10. Laparoscopic ovarian cystectomy for a benign teratoma in a 10-year-old girl.

    A 10-year-old girl was diagnosed with an 8-cm mature cystic teratoma. An outpatient ovary-conserving cystectomy was performed, and the girl recovered fully in 24 hours. We suggest that laparoscopy can be effective in the conservative management of some gynecologic disorders in properly selected children.
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ranking = 1
keywords = gynecologic
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