1/14. Management of severe and complicated malaria in the intensive care unit.malaria remains today one of the major health problems in the tropics with increased morbidity and mortality. The most serious complications are caused by plasmodium falciparum, which, in contrast to the benign malarias, may progress to a life-threatening multi-system disease. Our case concerns a young woman in the 14th week of pregnancy, admitted to the ICU in a coma, with pulmonary oedema, haemolytic anaemia, renal failure and thrombocytopenia as complications of P. falciparum malaria. The case is discussed and possible explanations for the clinical picture and complications of P. falciparum malaria are given in the light of experiences from the literature.- - - - - - - - - - ranking = 1keywords = malaria (Clic here for more details about this article) |
2/14. Profound thrombocytopenia in plasmodium vivax malaria.In india, malaria is endemic and commonly caused by plasmodium vivax and P. falciparum. thrombocytopenia is a common finding in falciparum infection but is rare in P. vivax infection. We report profound thrombocytopenia in a 43-year-old female patient due to P. vivax infection. The platelet count was as low as 5 x 10(9)/liter, such severe thrombocytopenia has never been reported in vivax malaria.- - - - - - - - - - ranking = 12.012553981826keywords = vivax malaria, vivax, malaria (Clic here for more details about this article) |
3/14. Immunoglobulin therapy for severe thrombocytopenia complicating falciparum malaria.A 12-year-old Saudi boy with falciparum malaria developed profound thrombocytopenia with associated significant bleeding. Immunoglobulin was used to treat this case.- - - - - - - - - - ranking = 0.71428571428571keywords = malaria (Clic here for more details about this article) |
4/14. thrombocytopenia after kidney transplantation.We report a case of posttransplant malaria in which the patient developed progressive thrombocytopenia after receiving living related donor kidney transplantation. The donor, who flew in from sri lanka for the procedure, had suffered from malaria 18 months earlier. malaria should be suspected in transplant patients receiving organs from donors originating from countries with a high prevalence of malaria.- - - - - - - - - - ranking = 0.42857142857143keywords = malaria (Clic here for more details about this article) |
5/14. plasmodium vivax malaria presenting with severe thrombocytopenia.plasmodium falciparum and plasmodium vivax malaria are endemic infections in india and are commonly associated with mild hematological abnormalities. Severe thrombocytopenia is common in isolated falciparum and mixed falciparum/vivax malaria, but is very rare in isolated P.vivax infection. We hereby report a case of severe thrombocytopenia (platelet count of 8x10(9)/L) in a case of vivax malaria. This is only the second case ever reported in the literature of such profound thrombocytopenia in a case of isolated P.vivax malaria.- - - - - - - - - - ranking = 17.975402836302keywords = vivax malaria, vivax, malaria (Clic here for more details about this article) |
6/14. An unusual adhesion between red-cells and platelets in falciparum malaria.A Thai female patient infected with P. falciparum had 80 per cent P. falciparum infected red cells at ring stage in the peripheral blood smear. The complications included anemia, thrombocytopenia, acute renal failure and pulmonary edema. A marked decrease in platelets number, low hemoglobin, low hematocrit and decreased red blood cell count were detected. More than 70 per cent of total platelets detected in the blood smear were binding to parasitized red blood cells. The number of binding platelets declined with decreasing per cent parasitized red cells. It was also noted that some platelets (10-20%) adhered to nonparasitized red cells. An increased number of large lymphocytes was shown by increased numbers of large unstained cells (LUC) by H* 1 automated analyzer. The peripheral blood smear showed abnormal binding of platelets to the infected red cells more frequently than to non infected red cells and free platelets on the day of high parasitemia. This abnormal phenomena was related to the number of platelets in the circulation. When the parasitized red cells were not detected in the blood smear, the number of platelets in the circulation had returned to normal.- - - - - - - - - - ranking = 0.57142857142857keywords = malaria (Clic here for more details about this article) |
7/14. plasmodium vivax malaria presenting with severe thrombocytopenia.Haematological changes are common in malaria. thrombocytopenia is a common finding in falciparum infection but rare in plasmodium vivax. We report a case of 7-year-old male patient presenting with fever, petechial rash, and platelet counts of 6 x 10(9)/l due to plasmodium vivax malaria.- - - - - - - - - - ranking = 11.477758136538keywords = vivax malaria, vivax, malaria (Clic here for more details about this article) |
8/14. A rare cause of anemia and thrombocytopenia in a newborn: congenital malaria.A newborn with fever and jaundice was referred to our hospital with anemia and thrombocytopenia of unknown origin. The patient's mother suffered from malaria infection during the third trimester of her pregnancy, but she did not accept medical therapy. On physical examination the newborn showed mild splenomegaly and jaundice. Laboratory tests revealed marked anemia with a hemoglobin value of 7.7 g/L and thrombocytopenia with platelet numbers of 17,000/mm3. plasmodium vivax was detected in blood smear. Oral therapy with chloroquine and primaquine was started. This patient is the second case of congenital malaria reported from turkey, and shows that the diagnosis of congenital malaria should be considered in infants with suspected congenital infection who are born to mothers with a history of malarial disease. We emphasize the importance of adequate antenatal medical therapy during pregnancy.- - - - - - - - - - ranking = 1.4102550655014keywords = vivax, malaria (Clic here for more details about this article) |
9/14. Gastrointestinal bleeding in malaria.Hematological alterations are frequent in patients with malaria. However, these rarely manifest clinically, except for symptoms due to anemia. Two cases with gastrointestinal hemorrhage as a complication of malaria are reported.- - - - - - - - - - ranking = 0.85714285714286keywords = malaria (Clic here for more details about this article) |
10/14. splenectomy in onyalai. A report on 5 cases.Onyalai is an acquired immune thrombocytopenia with 10% mortality. Conservative measures such as traditional medicines, corticosteroids and blood transfusion have not always controlled severe bleeding or prevented death. Five patients (2 male, 3 female) with onyalai who had uncontrollable haemorrhage, thrombocytopenia and documented previous attacks of severe bleeding, underwent splenectomy. The patients were screened for malaria, sickle-cell anaemia and bilharzia. vitamin k and epsilon-aminocaproic acid were administered pre-operatively, and fresh blood was given during surgery. The duration of follow-up varied between 280 and 544 days. There were no operative complications. Bleeding stopped in all patients and the platelet counts increased within 24 hours. All achieved normal platelet counts, but these were not always sustained. Three patients remained free of disease with normal platelet counts up to days 539, 539 and 544 of follow-up. Two patients had a recurrence of bleeding and died from cerebral haemorrhage and haemorrhagic shock.- - - - - - - - - - ranking = 0.14285714285714keywords = malaria (Clic here for more details about this article) |
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