Cases reported "Tic Disorders"

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11/90. PANDAS: pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections--an uncommon, but important indication for tonsillectomy.

    Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, also know as "PANDAS," is well described in the neurologic and psychiatric literature. PANDAS is associated with obsessive compulsive disorders (OCD) and tic disorders. The streptococcal infections may trigger an autoimmune reaction that exacerbates these conditions. Recurrent streptococcal tonsillitis is one of the recurrent infections associated with PANDAS. This paper reviews the case reports of two brothers, one with OCD and the other with a tic disorder, both of whom improved significantly after undergoing adenotonsillectomy for treatment of their recurrent tonsillitis. A review of the pathophysiology and current understanding of PANDAS is presented.
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ranking = 1
keywords = tic disorder, tic
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12/90. Eye movement tics.

    An 8-year-old girl presented with opsoclonus-like eye movement and an 18 month history of intermittent facial tics. Investigations were all normal. Electro-oculography showed the eye movements to be of variable amplitude (10-40 degrees), with no intersaccadic interval, and with a frequency of 3-4 Hz. saccades, smooth pursuit, optokinetic, and vestibular reflexes were all normal. These abnormal eye movements eventually disappeared. It is thought that they were a form of ocular tics.
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ranking = 0.15912011087817
keywords = tic
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13/90. Recumbent tic.

    A 59-year-old man with a 30-year history of an unusual movement disorder characterised by involuntary axial spasms that occur only in recumbency is described. Clinical and electrophysiological evidence suggest that this disorder is best characterised as a simple tic of unusual form. We have coined the term "recumbent tic" to describe this disorder.
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ranking = 0.136388666467
keywords = tic
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14/90. A case of adult onset tic disorder following carbon monoxide intoxication.

    BACKGROUND: adult onset tic disorders are usually secondary in origin. We report a case of adult onset tic disorder following carbon monoxide (CO) intoxication with typical magnetic resonance imaging features. CASE REPORT: A 36-year-old woman developed temporarily suppressible patterned movements on her face, neck, and shoulder associated with sensory discomfort after CO poisoning. Magnetic resonance images showed bilateral symmetric cavitary changes in the globus pallidus. clonazepam relieved much of her symptoms. CONCLUSION: Our patient developed a monosymptomatic tic disorder following CO intoxication. This further supports that altered outflow signals from the basal ganglia, especially the globus pallidus, may contribute to the development of tic disorders.
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ranking = 4.0681943332335
keywords = tic disorder, tic
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15/90. Functional brain imaging in Sydenham's chorea and streptococcal tic disorders.

    Group A streptococcal infections cause a wide range of neuropsychiatric disorders, such as Sydenham's chorea, tics, obsessive-compulsive disorders, and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). Structural (computed tomography and magnetic resonance imaging) and functional (positron emission tomography, single-photon emission computed tomography) imaging studies in patients with Sydenham's chorea have suggested reversible striatal abnormalities. The objective of this study was to investigate the cerebral perfusion patterns of the subcortical structures by using hexamethylpropylenamine oxime single-photon emission computed tomography (HMPAO-SPECT) in seven cases of Sydenham's chorea and two cases of streptococcal tic disorder. HMPAO-SPECT studies revealed a hyperperfusion pattern in two and a hypoperfusion pattern in five of the chorea patients and in two patients with tic disorder. The results are discussed in relation to the duration and severity of the symptoms and the response to therapy. Functional imaging findings can be variable in Sydenham's chorea, and hyperperfusion of the striatum and thalamus could be an indicator of the response to therapy and the severity of symptoms. However, the number of cases so far investigated by either SPECT or positron emission tomography is still too limited to draw any firm conclusions.
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ranking = 3.0681943332335
keywords = tic disorder, tic
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16/90. Stress fracture of the medial clavicle secondary to nervous tic.

    The clinical and radiological characteristics of swelling in the region of the medial clavicle may suggest the presence of a neoplastic or inflammatory lesion. This report describes a 27-year-old man with a painful tumor-like lesion over the medial clavicle, which was found to be a stress fracture caused by a nervous tic resulting from mental stress.
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ranking = 0.15912011087817
keywords = tic
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17/90. Candidate locus for Gilles de la tourette syndrome/obsessive compulsive disorder/chronic tic disorder at 18q22.

    Gilles de la tourette syndrome (GTS), obsessive compulsive disorder (OCD), and chronic tic disorder (CTD) are chronic, potentially debilitating neuropsychiatric disorders that often cluster in families. comorbidity data and family and linkage studies support the hypothesis that these phenotypes, in some cases, share a common etiology. Studies of chromosomal abnormalities associated with this phenotypic spectrum further show that GTS, OCD, and CTD may represent alternate manifestations of a shared genetic condition. We report on a 14-year-old girl with severe OCD and a t(2;18)(p12;q22) translocation. The patient's chromosome 18 breakpoint localizes to the same chromosomal band as two previously reported rearrangements associated with GTS, OCD, and CTD, and fine maps to a genomic position approximately 5 Mb from these rearrangements. The clustering of these three breakpoints within a relatively small genetic interval suggests that 18q22 is a promising region for containing a gene or genes of etiologic importance in the development of the GTS/OCD/CTD phenotypic spectrum.
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ranking = 2.5454628888223
keywords = tic disorder, tic
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18/90. adult-onset tic disorder, motor stereotypies, and behavioural disturbance associated with antibasal ganglia antibodies.

    The onset of tics in adulthood is rare and, unlike the childhood variety, there is commonly a secondary environmental cause. We present four cases (1 man, 3 women) with an adult onset tic disorder (mean age of onset, 36 years; range, 27-42 years) associated with the presence of serum antibasal ganglia antibodies (ABGA). One patient had motor tics and unusual motor stereotypies, 2 had multiple motor and vocal tics, and the remaining patient had motor tics only. Concomitant psychiatric disturbance was noted in 3 cases. In 2 cases, there was a close temporal relationship between upper respiratory tract infection and the subsequent onset of tics. Imaging was possible in three cases and was normal in two but revealed a lesion involving the right caudate and lentiform nuclei in the other. We suggest that there might be a causal relationship between ABGA and the clinical syndrome in these cases and that ABGA should be considered as a possible etiology for adult-onset tics.
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ranking = 2.6365156615466
keywords = tic disorder, tic, vocal tic, vocal
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19/90. Atomoxetine use associated with onset of a motor tic.

    patients with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for Tourette's Disorder and other tic disorders. Stimulant medications and bupropion have been associated with the onset or exacerbation of a tic disorder. The selective norepinephrine reuptake inhibitor, atomoxetine, has been proposed to be an alternative medication for patients with ADHD and a comorbid tic disorder. This paper reviews a case study in which the onset of a motor tic was associated with a trial of the medication atomoxetine. Further research is needed to determine if atomoxetine is an appropriate alternative medication in patients with ADHD and a comorbid tic disorder.
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ranking = 2.1136572220558
keywords = tic disorder, tic
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20/90. Stress fracture of the peroneal bone secondary to a complex tic.

    Complex tics have been widely reported in literature, especially in children with tourette syndrome. We describe the case of a fracture line of both peroneal bones in a 13-year-old child with tourette syndrome and obsessive-compulsive disorder. He was admitted to our hospital because of pain in his legs. radiography showed fractures of both peroneal bones, more marked on the left side. The clinical history was strongly suggestive of obsessive-compulsive disorder and tourette syndrome with associated simple and complex motor tics. Radiographic follow-up showed spontaneous resolution of the fractures.
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ranking = 0.136388666467
keywords = tic
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