Cases reported "Tick-Borne Diseases"

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1/7. Spotted fever in hong kong.

    A previously healthy 7-year-old hong kong-born Caucasian child developed sudden onset fever, followed by a generalized rash and systemic symptoms of rigor and prostration, mucous membrane involvement (conjunctivitis) and arthralgia. He lives in a rural area of hong kong and has been in contact with various domestic animals--rodents, dogs and cows. chloramphenicol 50 mg/kg/day was given on day 4 with rapid response. Subsequent Weil-Felix test and specific serology suggested the diagnosis of rickettsial infection of the spotted fever group. To our knowledge, this is the first confirmed case of spotted fever reported in hong kong.
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keywords = rickettsia
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2/7. Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the united states.

    ticks, including many that bite humans, are hosts to several obligate intracellular bacteria in the spotted fever group (SFG) of the genus Rickettsia. Only rickettsia rickettsii, the agent of rocky mountain spotted fever, has been definitively associated with disease in humans in the united states. Herein we describe disease in a human caused by Rickettsia parkeri, an SFG rickettsia first identified >60 years ago in Gulf Coast ticks (Amblyomma maculatum) collected from the southern united states. Confirmation of the infection was accomplished using serological testing, immunohistochemical staining, cell culture isolation, and molecular methods. Application of specific laboratory assays to clinical specimens obtained from patients with febrile, eschar-associated illnesses following a tick bite may identify additional cases of R. parkeri rickettsiosis and possibly other novel SFG rickettsioses in the united states.
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3/7. Fatal spotted fever rickettsiosis, kenya.

    We report a fatal case of rickettsiosis in a woman from the united states living in kenya, who had a history of tick exposure. Immunohistochemical staining of skin, kidney, and liver demonstrated spotted fever group rickettsiae. The clinical findings, severity, and fatal outcome are most consistent with rickettsia conorii infection.
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4/7. The first reported case of spotted fever in Fukui Prefecture, the northern part of central japan.

    A 53-year-old man visited Mt. Arashima-dake in Fukui Prefecture, and was infested by a tick-like organism. He visited a local clinic on July 12, 2004, complaining of high fever, general fatigue and rash. After several days without definite diagnosis, he was admitted to the Fukui Prefectural Hospital, where he was treated with minocycline hydrochloride for 10 days until recovery. His clinical symptoms on admission were high fever (39.6 degrees C), erythematous eruption, eschar on the right upper arm, and regional lymphoadenopathy. The epidemiological status and some clinical findings strongly suggested spotted fever (SF), and SF was confirmed based on the finding that his sera were reactive only to antigens of the SF group rickettsiae in the indirect immunoperoxidase analysis. This case is the first official report of SF rickettsiosis in Fukui Prefecture, the northern part of central japan.
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keywords = rickettsia
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5/7. Not only 'Flinders Island' spotted fever.

    AIM: To demonstrate that Flinders Island spotted fever (FISF), a spotted fever group rickettsial infection caused by Rickettsia honei, is found not only on Flinders Island (bass Strait), tasmania, but elsewhere in south-east Australia. methods: Cases of FISF were identified by rickettsial serology, culture and the detection of rickettsial dna via PCR. Isolates and PCR products were sequenced to identify the aetiological agent as R. honei. RESULTS: Three new cases of FISF were detected outside of Flinders Island. One on Schouten Island, south of the Freycinet Peninsula, tasmania, and two in south-eastern south australia (McLaren Vale and Goolwa). CONCLUSIONS: These cases show that FISF extends beyond Flinders Island and most likely has the same distribution across south-east Australia as its vector, the reptile tick Aponomma hydrosauri. FISF should be considered as a differential diagnosis in patients from south-eastern Australia presenting with fever, headache and rash following a tick bite.
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keywords = rickettsia
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6/7. Far eastern tick-borne rickettsiosis: identification of two new cases and tick vector.

    We recently reported the first documented cases of a new rickettsial disease caused by Rickettsia heilongjiangensis in the Russian far east (Far Eastern tick-borne rickettsiosis). Here we report the amplification of dna of R. heilongjiangensis from both the skin biopsy of an acutely ill patient and the tick removed from him prior to the disease development. The tick has been identified as Haemaphysalis spp. The clinical picture was that of a spotted fever group rickettsiosis and a seroconversion was noted with R. heilongjiangensis antigen. Screening testing of both species of Haemaphysalis ticks inhabiting Russian Far Eastern regions showed that up to 28.13% of H. concinnae and 4.48% of H. japonica douglasii ticks harbor R. heilongjiangensis. It has been concluded that H. concinnae may serve as the main vector for the transmission of R. heilongjiangensis. H. japonica douglasii ticks harbor several varieties of rickettsiae. dna of "Candidatus Rickettsia tarasevichiae," previously found in ixodes persulcatus ticks, was amplified from one male tick. Two sequenced complete gltA genes belong to the novel spotted fever group rickettsial species provisionally called here "Candidatus Rickettsia principis" variants Hjd54 and Hjd61. The rate of infection has been found to be not higher than 1.5%.
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keywords = rickettsia
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7/7. African tick-bite fever among international travelers--oregon, 1998.

    In May 1998, the oregon health Division received a report from a local physician that nine persons developed annular skin lesions accompanied by influenza-like symptoms within 8 days of leaving southern africa. All nine persons were members of a 34-person group from oregon that traveled to swaziland in April 1998 to participate in a 3-week humanitarian construction project. This report describes two cases of African tick-bite fever (ATBF) diagnosed in this group and underscores the importance of pretravel counseling about vectorborne illnesses and post-travel recognition of imported rickettsial diseases.
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