1/3. Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis.We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.- - - - - - - - - - ranking = 1keywords = conception (Clic here for more details about this article) |
2/3. Congenital toxoplasmosis after maternal infection before or slightly after conception.We report a newborn with typical lesions of congenital toxoplasmosis. Retrospectively, the time of infection could be located to or even before conception. A diagnostic work-up should be performed in every newborn whose mother presents persistent high antibody titers against toxoplasma during pregnancy.- - - - - - - - - - ranking = 1keywords = conception (Clic here for more details about this article) |
3/3. prenatal diagnosis of congenital toxoplasmosis transmitted by an immunocompetent woman infected before conception. Reims toxoplasmosis Group.We report a rare case of congenital toxoplasmosis transmitted by an immunocompetent woman infected before conception. Active toxoplasmosis was suspected due to persistent lymphadenitis with specific IgM, IgA, IgE antibodies. prenatal diagnosis based on amniocentesis and fetal blood sampling at 24 weeks' amenorrhoea was positive on amniotic fluid, and fetal infection was confirmed after termination. In our opinion such cases need the same monitoring as when seroconversion occurs during the first trimester. A pregnancy-free interval of six to nine months is recommended after proven patent toxoplasmosis seroconversion.- - - - - - - - - - ranking = 1keywords = conception (Clic here for more details about this article) |