Cases reported "Toxoplasmosis"

Filter by keywords:



Filtering documents. Please wait...

1/53. Two cases of toxoplasmic encephalitis in patients with acute T-cell leukaemia and lymphoma.

    Two cases of opportunistic cerebral infections in hiv-negative cancer patients due to chemotherapy induced immunosuppression are reported. A 61-year-old patient with low grade lymphoma (immunocytoma as referred to the Kiel classification) developed stereotactical biopsy proven toxoplasmic encephalitis 6 months after initiation of fludarabine treatment. The lymphoma had been diagnosed 8 years earlier and had been treated with several different regimens. In the second case, a 55-year-old patient developed neurological symptoms while in complete remission from acute T-cell leukaemia. The patient had been treated with a multidrug chemotherapy regimen including radiotherapy of the brain and intrathecal chemotherapy. When toxoplasmic encephalitis was bioptically diagnosed the patient was on maintenance chemotherapy with methotrexate and mercaptopurine for 12 months. The patients' characteristics and outcome are reported and the potential pathogenesis is discussed.
- - - - - - - - - -
ranking = 1
keywords = encephalitis
(Clic here for more details about this article)

2/53. Low levels of natural killer cells in pregnant women transmitting toxoplasma gondii.

    The role of cell-mediated immunity in the maternal-fetal transmission of toxoplasma gondii was investigated in 17 pregnant women with primary T. gondii infection, in 7 of whom fetal infection occurred. 18 healthy pregnant women were followed-up as controls. Fetal outcome was uneventful in six women who were treated early in pregnancy with spiramycin, while stillbirth due to T. gondii encephalitis occurred in the offspring of one patient who started with therapy at 34 weeks' gestation. All patients who transmitted T. gondii showed significant changes in the mean levels of immune cells. The most prominent finding was a significantly lower level of natural killer (NK) cells in the mothers transmitting T. gondii to the fetus compared with non-transmitters and controls both in the number (99.7 (71.8-107.5)/microl versus 320.9 (307.9-356.4)/microl and 172.1 (122.4-213.3)/microl: median (25 degrees-75 degrees). p<0.001) and the percentage of NK cells (4.0 /-1.5 per cent versus 13.2 /-2.3 per cent and 10.2 /-3.4 per cent; mean /-SD, p<0.001). Although limited by the small number of patients, our data suggest that the assessment of NK cells may be considered as a prognostic marker of primary T. gondii infection in pregnancy.
- - - - - - - - - -
ranking = 0.16666666666667
keywords = encephalitis
(Clic here for more details about this article)

3/53. Unusual encephalitic illnesses in a child with acute leukaemia in remission: possible role of measles virus and toxoplasma gondii.

    We report a girl who developed an encephalitic illness with visual loss after two years treatment for acute lymphoblastic leukaemia. The visual loss was found to be due to bilateral macular degeneration. She later developed radiological evidence of intracranial calcification and temporal lobe epilepsy. A second episode of encephalitis occurred when she had been off all antileukaemic treatment for three years and this left her with a right hemiparesis. Investigation suggested involvement with both measles virus and toxoplasma gondii as a cause for these illnesses.
- - - - - - - - - -
ranking = 0.16666666666667
keywords = encephalitis
(Clic here for more details about this article)

4/53. toxoplasma gondii myelitis in a patient with adult T-cell leukemia-lymphoma.

    adult T cell leukemia-lymphoma (ATL) caused by HTLV-I may be associated with severe immunosupression and several opportunistic infections. Toxoplasmic encephalitis is a common central nervous system opportunistic infection in severely immunosupressed patients, however spinal cord involvement by this parasite is rare. In this paper, we report a case of toxoplasmic myelitis in a patient with ATL.
- - - - - - - - - -
ranking = 0.16666666666667
keywords = encephalitis
(Clic here for more details about this article)

5/53. diagnosis of toxoplasma meningoencephalitis in a non-AIDS patient using PCR.

    We report herein a rare case of toxoplasma gondii meningoencephalitis in a non-AIDS patient. Although T. gondii itself was not detected in nucleated cells in peripheral blood and cerebrospinal fluid under the microscope, the polymerase chain reaction method effectively detected the B1 gene of T. gondii in the cells. A serological examination showed increased levels of the IgG but not the IgM antibody to T. gondii, suggesting reactivation of the infection in the brain.
- - - - - - - - - -
ranking = 0.89448449698805
keywords = encephalitis, meningoencephalitis
(Clic here for more details about this article)

6/53. Intracerebral toxoplasmosis presenting as a mass lesion.

    Intracerebral toxoplasmosis is an uncommon condition and for it a produce an intracerebral mass is rare. A case is reported in a patient also suffering from lymphosarcoma, who had received immunosuppressive therapy and who had recently had herpes zoster ophthalmica.
- - - - - - - - - -
ranking = 0.00021857380814798
keywords = herpes
(Clic here for more details about this article)

7/53. toxoplasma encephalitis in hiv: case report.

    In tanzania, no data are available on the prevalence of brain infection by toxoplasma in hiv-infected patients. A case of a 35-year old man with fulminant toxoplasma encephalitis (TE) is reported for the first time. TE was not suspected clinically in our patient who presented with a one week history of severe headache and treated empirically with antimalarial drugs. TE was diagnosed postmortem histologically by haematoxylin-eosin and immunohistochemical stain with P30 antibody for toxoplasma antigen. The findings in our case support the suggestion that a high index of suspicion for TE should be maintained in hiv-infected patients presenting with focal neurological symptoms. The case highlights the importance of autopsy studies in not only documenting a toxoplasma brain lesion but also in increasing the awareness for its diagnosis in hiv-infected patients in tanzania and other developing countries.
- - - - - - - - - -
ranking = 0.83333333333333
keywords = encephalitis
(Clic here for more details about this article)

8/53. Skeletal muscle toxoplasmosis in patients with acquired immunodeficiency syndrome: a clinical and pathological study.

    The present article describes the clinical and pathological findings in 5 human immunodeficiency virus (hiv)-infected patients with muscle toxoplasmosis. The patients had marked lymphopenia (5/5), with less than five CD4 cells/mm3 (3/3), when they developed fever (5/5), and multiorgan failure (5/5), including diffuse encephalitis, pneumonia, pancytopenia, and myopathy. Muscle involvement included weakness and wasting (4/5), myalgias (3/5), and high serum creatine kinase levels (3/3). serology for toxoplasmosis showed high IgG titers in 3 patients (3/4). Anti-toxoplasma therapy resulted in complete recovery in 2 patients. Muscle toxoplasmosis was detected by biopsy (3/5) or postmortem evaluation (2/5), and was identified using immunocytochemistry and electron microscopy. toxoplasma cysts were detected in 0.5 to 4% of muscle fibers close to or remote from necrotic fibers and inflammatory infiltrates. Muscle fibers strongly expressed the major histocompatibility complex class I antigen (2/2) as in polymyositis. We suggest that toxoplasma gondii should be sought by muscle biopsy in patients who have acquired immunodeficiency syndrome with fever, encephalitis, multiorgan dysfunction, and elevated serum creatine kinase levels of obscure origin.
- - - - - - - - - -
ranking = 0.33333333333333
keywords = encephalitis
(Clic here for more details about this article)

9/53. pathology of toxoplasma myocarditis in acquired immunodeficiency syndrome.

    Involvement of the myocardium by toxoplasma gondii is seen in patients of acquired immunodeficiency syndrome (AIDS), mostly in association with toxoplasma encephalitis. Only few patients die as a direct result of cardiac dysfunction. Clinico-pathological findings of three cases of toxoplasma myocarditis are reported, one of which presented and died due to massive pericardial effusion. All cases showed diffuse myocarditis with parasites on histopathological examination. incidence of toxoplasma myocarditis in patients dying with AIDS was 8.3% (3 out of 36 cases).
- - - - - - - - - -
ranking = 0.16666666666667
keywords = encephalitis
(Clic here for more details about this article)

10/53. Toxoplasmic meningoencephalitis in an immunocompetent host.

    central nervous system involvement due to toxoplasmosis in an immunocompetent host is very rare. We report a case of an immunocompetent patient who presented with suspected tuberculous meningoencephalitis but showed no clinical response to antitubercular therapy. Later, toxoplasmic meningoencephalitis was proved by positive serological testing for toxoplasmosis, supportive magnetic resonance imaging findings of the brain and a therapeutic response to co-trimoxazole and prednisolone. Therefore, toxoplasmosis should be considered in cases of suspected tuberculous meningoencephalitis that fail to respond to specific therapy.
- - - - - - - - - -
ranking = 1.2522782957833
keywords = encephalitis, meningoencephalitis
(Clic here for more details about this article)
| Next ->


Leave a message about 'Toxoplasmosis'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.