Cases reported "trachoma"

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1/14. Secondary keratoconus with corneal epithelial iron ring similar to Fleischer's ring.

    BACKGROUND: Fleischer's ring is considered to be a characteristic of keratoconus, but we have seen a ring similar to Fleischer's ring in patients with secondary keratoconus, in which the cornea becomes thinner secondarily for undetermined reasons. CASES: We report 6 cases of secondary keratoconus with a corneal epithelial ring similar to the Fleischer's ring pattern. OBSERVATIONS: In these 6 cases (2 men and 4 women), the causes of secondary keratoconus were trachoma in 2 cases, trauma in 2 cases, keratitis in 1 case and unknown etiology in one case. All showed thinning of the cornea and a corneal iron ring similar to Fleischer's ring pattern. The corneal button obtained after keratoplasty in 1 case showed the deposition of hemosiderin in the corneal epithelium after staining with Prussian blue. At the same time we confirmed the existence of iron in the corneal epithelium by x-ray ultimate analysis. CONCLUSIONS: All 6 patients we encountered had a past history of corneal disease in their childhood except for 1 case with unknown etiology. Primary keratoconus is also considered to develop by the early teens at the latest. These facts led us to an assumption that the occurrence of some abnormalities in the cornea during the growth period may result in iron deposition in the epithelium and thinning of the stroma. In light of these facts, abnormalities of the iron metabolism must be thoroughly investigated in considering the etiology of keratoconus. ( info)

2/14. Worldwide blindness.

    blindness affects approximately 42 to 52 million people worldwide. This article examines the major causes of blindness, including cataract, trachoma, glaucoma, onchocerciasis, nutritional deficiencies, and ocular trauma. Numerous case studies supplement the text. ( info)

3/14. Ocular rosacea can mimic trachoma: a case of cicatrizing conjunctivitis.

    PURPOSE: To report the case of a patient with upper eyelid chronic cicatrizing conjunctivitis and entropion, presumably secondary to ocular rosacea. methods: Case report and review of medical literature. RESULTS: The patient has a history of chronic cicatrizing conjunctivitis since 1999. Despite an extensive workup for other possible causes, the patient's known history of acne rosacea is the most substantive explanation for her ocular disease. CONCLUSION: The presence of chronic cicatrizing conjunctivitis affecting mainly the upper eyelids, previously thought to be unique to trachoma, can be associated with ocular rosacea. ( info)

4/14. Subepithelial reticular cicatrization following radial keratotomy in a patient with inactive trachoma.

    BACKGROUND: Opacification of the clear optical zone following radial keratotomy has not been observed before. methods AND RESULTS: The authors noted the appearance of subepithelial dense white reticular cicatrization in the central area following radial keratotomy in a patient with inactive trachoma and clear cornea. The corneal changes resulted in regression of the surgical effect and decrease in visual acuity. A good visual result was obtained by performing homoplastic myopic keratomileusis in situ. Clinical and histopathological findings are presented. CONCLUSIONS: patients undergoing radial keratotomy should be carefully screened for inactive trachoma which may contribute toward postoperative reticulate opacity of the central cornea. ( info)

5/14. Vernal keratoconjunctivitis and trachoma.

    Both vernal keratoconjunctivitis and trachoma affect young people, occur in hot, dry climates, and have a predilection for the limbus and upper tarsal conjunctiva. These two conditions may occur simultaneously and present the ophthalmologist with a diagnostic and therapeutic dilemma. ( info)

6/14. Infection with chlamydia trachomatis immunotype J associated with trachoma in children in an area previously endemic for trachoma.

    chlamydia trachomatis immunotype J was isolated from the eye of a five-year-old Navajo child with trachoma. This is the first such isolate from a patient in an area previously endemic for trachoma. Chlamydial infection of the genitals among the Navajo Indians is common, and we have isolated immunotype J from the genital tract of women in this area. This most recent case points to the occurrence of "genital" trachoma. This occurrence adds evidence to the assertion that trachoma may be caused by the "genital" immunotypes of C. trachomatis. Therefore, the traditional distinction between ocular and genital strains may be artifactual. ( info)

7/14. Ectopic epibulbar Fordyce nodules in a buccal mucous membrane graft.

    A 70-year-old man underwent oral mucous membrane grafts to the right eye for presumed trachoma at the ages 26 and 32 years. A superior limbic mass within the site of the graft was found in 1983; the mass was composed of mature sebaceous glands compatible with the lesions called Fordyce nodules when located in the buccal mucosa. Recession of the levator aponeurosis and partial excision of the mass restored the upper eyelid's normal position, and visual acuity in this eye improved from 20/300 to 20/40. ( info)

8/14. amyloidosis of the conjunctiva--an unusual complication of trachoma: a case report.

    A 25-year-old Shona woman with chronic bilateral trachoma developed bilateral, painless, massive conjunctival tumefactions over a period of 2 years. Subtotal removal of the masses yielded tissue which showed the typical staining characteristics of amyloid and contained a heavy plasmacytic infiltration. Systemic examination revealed no other abnormality. The trachoma provided the setting in which the amyloid reaction developed. ( info)

9/14. Fibrous histiocytoma of the lacrimal sac.

    Fibrous histiocytoma is a rare tumor whose ocular manifestations usually involve the orbit or, less commonly, the conjunctiva and ciliary body. We have treated two patients with fibrous histiocytoma of the lacrimal sac. One, a 62-year-old woman who had had hordeolum and trachoma, had a visual acuity of counting fingers at 1 m in the affected eye. The fellow eye had been enucleated ten years previously. The entire lacrimal sac was surgically removed and a brown cystic tumor measuring 28 x 12 x 10 mm was found. The second patient, a 32-year-old man, had undergone an unsuccessful dacryocystectomy for epiphora. When he underwent a dacryocystorhinostomy some months later, a mass measuring 20 x 15 x 12 mm was found in the wall of the lacrimal sac. Microscopic examination of the two excised lacrimal sacs showed that the walls were thickened by cells resembling fibroblasts and by cells resembling histiocytes. The fibroblasts were characterized by collagen production, were fusiform or oval in shape, and were arranged in bundles. The histiocytes were larger and had abundant (and sometimes vacuolated) cytoplasm. All the cells appeared to be mature. ( info)

10/14. Childhood trachoma in a nonendemic area. Danish trachoma patients and their close contacts, 1963 to 1973.

    During ten years of study of chlamydia trachomatis eye infections, trachoma was diagnosed in 14 Danish patients with onset during childhood. Clinical findings in the eye were characteristic of classical trachoma. The infecting C trachomatis immunotype was identified in all but one case. At the time of diagnosis, seven patients were still children (6 to 10 years of age), three were teenagers, and four were adults. In five young girls the disease was extremely severe. Delay in proper diagnosis and adequate therapy contributed to the prolongation and severity of the disease. Failure to diagnose is attributed to widespread opinion and teaching of physicians in Western countries that trachoma eye disease has disappeared. Studies of family members and other contacts of the patients contributed to an understanding of the pathogenesis of this disease. The source of initial eye infection with C trachomatis organisms in these cases was thought to be the birth canal. It was further postulated that reinfection of the eyes of these children occurred either from a reservoir in their own or their mother's genital tract. ( info)
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