Cases reported "Tuberculosis, Pulmonary"

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1/4. Massive intrathoracic haemorrhage after CT-guided lung biopsy.

    CT-guided lung biopsy is now widely performed for tumorous lesions in the lung, and both its usefulness in this context and the associated complications have been well described in the literature. Although severe complications are rare, we describe a case in which massive intrathoracic haemorrhage developed after lung biopsy and necessitated emergency operation for control. Intraoperative findings suggested that the source of the haemorrhage was a fibrous, cord-like substance present at the site of adhesion associated with old tuberculosis. We attributed this haemorrhage to a pneumothorax, which developed after lung biopsy and caused the new vessels penetrating the centre of the fibrous, cord-like substance to stretch and rupture. Numerous cases have been reported of spontaneous haemopneumothorax precipitated by spontaneous pneumothorax and resulting from the rupture of such vessels.
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keywords = haemorrhage
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2/4. Pulmonary tuberculosis and extreme prematurity.

    A mother, newly found to be positive for hiv, delivered her first baby at 25 weeks gestation. The infant initially did well in spite of a symptomatic patent duct and a severe intraventricular haemorrhage, but became severely unwell needing further respiratory support on day 18. Acid fast bacilli were found in endotracheal secretions. After the baby's death, the bacilli were confirmed to be mycobacterium tuberculosis, and the same organism was grown from the mother's urine. The case raised challenging issues in relatively uncharted territory in terms of treatment of the infant, public health issues, ethical decision making, and media management.
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ranking = 0.14285714285714
keywords = haemorrhage
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3/4. Aplastic anaemia associated with anti-tuberculosis chemotherapy.

    3 cases of aplastic anaemia occurring in association with anti-tuberculosis chemotherapy are reported. The patients had been on anti-tuberculosis chemotherapy for 13, 11 and 14 months, respectively, prior to the diagnosis of aplastic anaemia. Agents used included streptomycin, thiacetazone, isoniazid, p-aminosalicylic acid and dimethylcarbazine. Recovery from aplasia did not occur 6. 1.5 and 0.8 months, respectively, after the discontinuation of the suspect myelotoxic agents and despite the use of myelostimulatory agents. All 3 patients died of haemorrhage secondary to thrombocytopenia. The observations are consistent with a protracted and probably irreversible damage of the bone marrow by anti-tuberculosis agent(s) in susceptible individuals.
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ranking = 0.14285714285714
keywords = haemorrhage
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4/4. Massive haemoptysis caused by mycobacterium xenopi.

    A 62-year-old man presented with haemoptysis and radiographic features compatible with pulmonary tuberculosis. His course was complicated by severe haemoptysis that required surgical lobectomy. mycobacterium xenopi was cultured from sputum and lung tissue. The post-operative course was complicated by gastro-intestinal haemorrhage and the patient died.
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ranking = 0.14285714285714
keywords = haemorrhage
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