Cases reported "Urethral Neoplasms"

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1/33. Lymphatic mapping and intraoperative lymphoscintigraphy for identifying the sentinel node in penile tumors.

    Lymph node mapping has become an integral part of the management of melanoma and breast cancer with regard to both staging and treatment. We report our technique for lymphatic mapping and intraoperative lymphoscintigraphy applied to a patient with penile melanoma. This technique may improve the sensitivity of identifying the sentinel lymph node in patients with malignant penile lesions.
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ranking = 1
keywords = melanoma
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2/33. A large primary malignant melanoma of the female urethra.

    We present a case of large, primary malignant melanoma of the female urethra with poor prognosis in this case report. Malignant melanoma is one of the rare tumors of the female urethra and accounts for 0.2% of all malignant melanoma cases. Large (5.6 cm in diameter), primary malignant melanoma of the female urethra is exceedingly rare.
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ranking = 13.116896722977
keywords = malignant melanoma, melanoma
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3/33. Primary malignant melanoma of the male urethra.

    BACKGROUND: We describe a rare case of malignant melanoma originating from the male urethra. methods/RESULTS: This case, which presented a tan-colored lesion at the distal urethra on urethroscopy, was considered as transitional cell carcinoma by transurethral biopsy. Pathologic examination of widely resected urethra revealed scattering cells, which included melanin granules in cytoplasm, and then immunohistochemical stains established the diagnosis as amelanotic melanoma. Although partial penectomy and inguinal lymph node dissection were subsequently performed, 7 months later, total cystourethrectomy was required because of multifocal recurrence at the residual urethra. CONCLUSIONS: In cases of amelanotic melanoma, it should be noted that a lack of melanin granules in tumor cells may lead pathologists and urologists to a misdiagnosis due to the histologic non-specific appearance. With respect to surgical management, of significance is the fact that malignant melanoma may progress multifocally along the total urethra; therefore, total urethrectomy should be considered as radical surgery for the primary site, even if the tumor is confined to the distal urethra.
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ranking = 11.814482905409
keywords = malignant melanoma, melanoma
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4/33. Surgical technique for the conservative management of distal urethral melanoma.

    Urethral melanoma is very rare and pathological diagnosis is important. The prognosis remains poor irrespective of the treatment modality. Rare cases of long-term survival have been reported, one of them following conservative management. An initial attempt at conservative resection is worth considering to offer a better quality of life to the patient for as long as possible. We describe a technique of organ-sparing resection in the management of urethral melanoma along with the follow-up protocol that we adapted.
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ranking = 3
keywords = melanoma
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5/33. Primary malignant melanoma of the male urethra.

    We report a case of primary malignant melanoma of the male urethra in a patient whose penile shaft was successfully preserved, but who proceeded to acute renal failure (ARF) after interferon (IFN)-beta adjuvant immunotherapy. Primary malignant melanoma of the male urethra is rare and usually shows highly malignant potential. Therefore, urologists must often perform phallectomy, which impacts on the patient both sexually and mentally. A 64-year-old man presented at Saiseikai Sendai Hospital with asymptomatic gross hematuria and was diagnosed as distal urethral tumor. We predicted the highly malignant potential of this tumor from the urethroscopic finding and from urinary cytological examination. We did not select trans-urethral resection (TUR), but selected partial urethrectomy. This patient proceeded to ARF 1 month after natural IFN-beta treatment as an adjuvant immunotherapy. As IFN-beta rarely induces the delayed renal failure, urologists should be aware of renal dysfunction after IFN-beta therapy for the treatment of malignant melanoma.
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ranking = 12.616896722977
keywords = malignant melanoma, melanoma
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6/33. Primary malignant melanoma of the urethra.

    Primary malignant melanoma of the urethra is an aggressive neoplasm associated with a poor prognosis. The outcome is dependent on early diagnosis and surgical intervention. However, the diagnosis is often delayed as a result of difficulties related to differentiating this lesion from other disorders. Such difficulties result from the variety of clinical and pathologic presentations that are common to melanoma. We report a case of primary malignant melanoma of the urethra with subsequent retrograde seeding of the bladder initially diagnosed and managed as invasive urothelial carcinoma.
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ranking = 11.314482905409
keywords = malignant melanoma, melanoma
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7/33. Primary malignant melanoma of the male urethra.

    We report a case of primary malignant melanoma of the male urethra, increasing the total number of reported cases to 31. The experience with our case suggests that urinary cytology is a diagnostic method for malignant melanoma and essential in the preoperative diagnosis of this disease.
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ranking = 10.814482905409
keywords = malignant melanoma, melanoma
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8/33. Primary malignant melanoma of male urethra.

    A case of primary malignant melanoma of the male urethra is reported. Treatment included partial urethrectomy, bilateral inguinal and iliac lymphadenectomy, and post-surgical systemic chemotherapy. After thirty-six months, the patient is alive with cutaneous, pelvic lymph node, and gastric metastases.
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ranking = 9.0120690878407
keywords = malignant melanoma, melanoma
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9/33. A patient with multiple, malignant melanomas of the lower genital tract.

    Malignant melanomas of the female genital tract are uncommon lesions. A patient with multiple cutaneous, vulvar melanomas and a subsequent malignant melanoma of the cervix is described.
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ranking = 10.012069087841
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

10/33. Early 'invasive' malignant melanoma of the glans penis and the male urethra. Report of a case and review of the literature.

    A 40-year-old male with early 'invasive' malignant melanoma of the glans penis and meatus urethrae externus is presented. Early stages of primary melanoma of the glans penis and the male urethra are distinctly rare and are often clinically indistinguishable from penile lentigo, melanosis and melanocytic nevus on the genitalia. In order to avoid large and useless surgery on such a delicate location we propose a punch biopsy with subsequent histological examination prior to definitive surgical procedure. Whereas malignant melanoma of the penis with a thick Breslow index is treated with extended surgical management, only local excision of the tumor without groin dissection was performed in our patient.
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ranking = 11.314482905409
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)
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