Cases reported "Urogenital Neoplasms"

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1/5. Genitourinary neurofibromatosis in a child presenting with an enlarged penis and scrotum.

    We report on a boy with genitourinary neurofibromatosis. The patient presented with bilateral hydronephrosis, and a markedly enlarged penis and scrotum. laparotomy showed a mass occupying the small pelvic cavity. Histologically, the mass was a plexiform neurofibroma. The enlarged genitalia seemed to be caused by involvement of neurofibromatosis. The patient underwent a successful ileal conduit diversion.
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keywords = neurofibroma
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2/5. Neurofibromatosis involving the lower urinary tract in children. A report of three cases and a review of the literature.

    Three children with neurofibromatosis involving the lower urinary tract are reported and their clinical, radiological and pathological findings are described. Lower urinary tract involvement in neurofibromatosis has previously been reported in 17 children, 12 of whom had other stigmata of von Recklinghausens disease. Lower urinary tract involvement may be asymptomatic and can be found incidentally. Every case with neurofibromatosis presenting with what may appear to be even only insignificant urinary symptoms should be thoroughly investigated urologically. Symptoms are usually related to urinary tract obstruction or neurogenic bladder dysfunction due to the involvement of the nerves supplying the bladder. urinary diversion is the treatment of choice as surgical removal of the extensive tumour is seldom feasible. Following treatment the prognosis for survival appears to be good.
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ranking = 0.42857142857143
keywords = neurofibroma
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3/5. Transperineal biopsy leads to the diagnosis of genitourinary neurofibromatosis in association with a congenital malformation of the urinary tract.

    OBJECTIVE: A case of genitourinary fibromatosis with associated anomalies is presented. methods: Clinical evaluation included ultrasonography, urography, CT scan and MR image. ultrasonography-guided perineal biopsy was performed with a 14-gauge Tru-cut needle. RESULTS: Rectal examination revealed a very hard prostatic mass in the 22-year-old patient. The histological result and clinical data indicated the diagnosis of genitourinary von Recklinghausen disease. CONCLUSION: We report a very rare case of genitourinary neurofibromatosis associated with congenital anomalies of the urinary tract. The diagnosis was obtained with US-guided transperineal biopsy.
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ranking = 0.71428571428571
keywords = neurofibroma
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4/5. Plexiform neurofibroma involving the genitourinary tract in children: case reports and review of the literature.

    We report extensive genitourinary neurofibroma in two children who presented with massive bilateral hydroureteronephrosis and a thick-walled bladder. The best radiologic technique to stage the disease and determine treatment is magnetic resonance imaging. Management of extensive genitourinary neurofibroma is controversial. Based upon our experience and a review of the literature, aggressive surgery should be approached cautiously.
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ranking = 0.85714285714286
keywords = neurofibroma
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5/5. Principles in management of complex pediatric genitourinary plexiform neurofibroma.

    Neurofibromatosis is a hamartomatous disorder of neural crest derivation characterized by cutaneous pigmentation and tumor formation in various tissues. Visceral involvement is typically insidious, progressive, and difficult to treat. Plexiform neurofibroma of the urinary tract is rare. Involvement of nearly every genitourinary structure by these lesions has been reported, with the bladder being most commonly involved. In part due to the small number of patients seen at any one institution and the highly variable location and extent of this disease process, a plan for management of individuals with genitourinary neurofibromatosis has not been proposed. In an attempt to define specific goals in treatment of such patients, we reviewed our population of 260 pediatric patients with type 1 neurofibromatosis. We present our series of 5 patients with complex genitourinary lesions and describe specific management principles.
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keywords = neurofibroma
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