Cases reported "Ventricular Fibrillation"

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11/64. Electrical storms in an ICD-recipient with 429 delivered appropriate shocks: therapeutic management with antiarrhythmic drug combination.

    The case of a 65 year old man with ischemic cardiomyopathy, an ICD device and recurrent electrical storms is presented. The patient had been implanted with an ICD device due to aborted sudden death. The first electrical storm occurred 12 months later. It was terminated by the administration of intravenous amiodarone and the patient was discharged on maintenance dose amiodarone and b-blocker. After a period of 3 months during which the patient remained asymptomatic, a second arrhythmic clustering occurred and it was controlled by the addition of mexiletine. A total number of 429 appropriate shocks had been delivered by the device. Thereafter and for a seven month follow-up period, the patient remains asymptomatic under this combination of antiarrhythmic drugs.
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ranking = 1
keywords = cardiomyopathy
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12/64. Ventricular assist device support for management of sustained ventricular arrhythmias.

    We describe herein the cases of 2 patients who had ventricular arrhythmias. In one, a short-term biventricular assist device, the ABIOMED BVS 5000, was placed because the patient had sustained ventricular tachycardia and could not be weaned from cardiopulmonary bypass. Excellent hemodynamic support was maintained for several days while the antiarrhythmic therapy was maximized. Sinus rhythm was restored, and the patient was successfully weaned from the ventricular assist device. However, the substrate for the arrhythmia persisted, and a recurrence, 1 week later, resulted in the patient's death. In the 2nd patient, the use of an implantable left ventricular assist device was successful in temporarily alleviating the ventricular tachycardia associated with ischemic cardiomyopathy. However, after 2 days of device assistance, the patient experienced a recurrence of the tachycardia, which degenerated into ventricular fibrillation with a marked deterioration in the patient's hemodynamics. The arrhythmia persisted despite multiple attempts at external cardioversion, and internal cardioversion and placement of an automatic implantable cardioverter-defibrillator were necessary. This treatment, along with repeated boluses of amiodarone, led to successful suppression of the arrhythmias, and the patient eventually underwent transplantation. The mechanical hemodynamic support of the circulation by ventricular assist devices was effective in supporting these 2 patients who had sustained ventricular arrhythmias.
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ranking = 1
keywords = cardiomyopathy
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13/64. Prolonged sustained ventricular fibrillation without loss of consciousness in patients supported by a left ventricular assist device.

    patients with cardiomyopathy of either ischemic or nonischemic origin are at increased risk for malignant ventricular arrhythmias. Normally sustained ventricular fibrillation (VF) leads to death very rapidly. We report two patients who remained in sustained VF, supported by a left ventricular assist device, for a prolonged period of time. perfusion pressure through the device was sufficient to allow the patients to remain awake and responsive for several hours while in VF. The cases represent two of the longest reported episodes of sustained VF recorded in awake patients implanted with such devices.
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ranking = 1
keywords = cardiomyopathy
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14/64. role of ventricular tachycardia surgery and catheter ablation as complements or alternatives to the implantable cardioverter defibrillator in the 1990s.

    Although the implantable cardioverter defibrillator is used increasingly, other nonpharmacological approaches have their indications and merits. Furthermore, as the natural history of ventricular tachyarrhythmias or their underlying structural cardiac abnormality, i.e., coronary artery disease, dilated cardiomyopathy, arrhythmogenic right ventricular disease, etc. change, the mode of therapy may be modified accordingly. Because of the disappointing results of the CAST study in previously asymptomatic patients after myocardial infarction and the evidence that failure of one or two antiarrhythmic drugs tested by programmed ventricular stimulation in patients with documented sustained ventricular tachycardia or fibrillation predicts further drug failure, there will be a significant increase in the use of implantable cardioverters defibrillators in the 1990s. However, care should be taken to avoid inappropriate use of these devices.
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ranking = 115.47914781616
keywords = arrhythmogenic, arrhythmogenic right, cardiomyopathy
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15/64. Cardiomyopathy in an adult with Bartter's syndrome and hypokalemia. Hemodynamic, angiographic and metabolic studies.

    A case of an adult with Bartter's syndrome (hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis) is described; the patient had the unusual manifestation of cardiomyopathy, probably secondary to severe hypokalemia. Results of metabolic studies and kidney biopsy were consistent with Bartter's syndrome; angiographic and hemodynamic findings were abnormal. The cardiomyopathy was confirmed at autopsy after the patient's sudden death. Conclusions from this case are that severe hypokalemia can pose a serious threat both immediately in the form of dangerous arrhythmias and in the long term in the form of cardiomyopathy.
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ranking = 3
keywords = cardiomyopathy
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16/64. Cardioverter defibrillator implantation in a child with isolated noncompaction of the ventricular myocardium and ventricular fibrillation.

    isolated noncompaction of the ventricular myocardium is a rare unclassified cardiomyopathy and is thought to be due to arrest of myocardial morphogenesis. In fetal life, it is characterized by an excessively prominent trabecular meshwork and deep intratrabecular recesses, and occurs in the left ventricle in the absence of structural heart disease. echocardiography provides evidence for the diagnosis. The noncompacted ventricular myocardium may be accompanied by depressed ventricular function, systemic embolism, wolff-parkinson-white syndrome, left bundle branch block, and ventricular arrhythmia. Although onset of symptoms is frequently delayed until adulthood, symptomatic children have a poor prognosis. In this report, we describe a case of 6-year-old girl who had a history of recurrent syncope. Transthoracic echocardiographic examination showed a localized prominent trabeculation and deep intratrabecular recesses at the inferoapical region of the left ventricle. She had several episodes of ventricular fibrillation which was refractory to pharmacological treatment. An implantable cardioverter defibrillator (ICD) was successfully operated three times during follow-up.
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ranking = 1
keywords = cardiomyopathy
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17/64. Arrhythmogenic right ventricular cardiomyopathy with left ventricular involvement and aortic dissection.

    Ten years ago, a 59-year-old patient presented with ventricular fibrillations. The resting ECG showed findings typical for ARVC. echocardiography and ventriculography confirmed the diagnosis of ARVC showing a dilated right ventricle with aneurysms. MRI showed additional fatty replacement of the LV. Furthermore, the diagnosis of a chronic aortic dissection was established. Two years after ICD implantation, the patient died of progressive right heart failure. On autopsy, most of the RV and parts of the LV were replaced by fatty tissue, and the media of the aorta showed degenerative changes. A pathogenetic link between the two diseases remains speculative at this time.
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ranking = 4
keywords = cardiomyopathy
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18/64. Electrical storm as initial presentation of arrhytmogenic right ventricular cardiomyopathy in an elderly woman.

    arrhythmogenic right ventricular dysplasia (ARVD) is an unusual cause of electrical storm in the elderly. We report the case of a 76-year-old woman with no previous known disease who developed recurrent ventricular tachycardia and fibrillation. Postmortem examination revealed histological features of arrhythmogenic right ventricular dysplasia.
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ranking = 419.87839891674
keywords = ventricular dysplasia, arrhythmogenic, right ventricular dysplasia, arrhythmogenic right, arrhythmogenic right ventricular dysplasia, cardiomyopathy, dysplasia
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19/64. ventricular fibrillation without overt cardiomyopathy as first presentation of organic cation transporter 2-deficiency in adolescence.

    This case report describes ventricular fibrillation without overt cardiomyopathy as the presenting symptom of primary carnitine deficiency due to organic cation transporter 2 (OCTN2)-deficiency in a 15-year-old girl. Normally this disease presents early in life with hypoketotic hypoglycemia, muscle weakness, and/or cardiomyopathy. The patient fully recovered after carnitine supplementation. Recognition of this disease is important because its treatment is easy and effective.
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ranking = 6
keywords = cardiomyopathy
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20/64. Focal origin of ventricular fibrillation in a patient with ischemic cardiomyopathy.

    A 65-year-old patient with history of ischemic cardiomyopathy admitted to the hospital for chest pain and subsequently experienced incessant ventricular fibrillation (VF), requiring repeated defibrillation. Coronary angiogram was unchanged, compared to a study a year before, and acute ischemia was not considered to be the etiology of the VF. A particular premature ventricular contraction morphology was noted on telemetry prior to each episode of VF. The patient subsequently underwent successful radiofrequency ablation of a focus in the left ventricular free wall. Careful examination of initiating foci of VF or polymorphic ventricular tachycardia, with radiofrequency ablation in appropriate cases, could be potentially life-saving.
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ranking = 5
keywords = cardiomyopathy
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