Cases reported "Yersinia Infections"

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31/218. Infective mesenteric adenitis masquerading as relapsed non-Hodgkin's lymphoma.

    Bulky mesenteric lymphadenopathy and B symptoms in a patient with a prior history of relapsed histologically aggressive non-Hodgkin's lymphoma would usually be attributed to recurrent disease. In the case described here, recurrent lymphadenopathy was found to be due to probable Yersinia infection, highlighting the need for rebiopsy of tissue in these circumstances wherever possible. ( info)

32/218. yersinia enterocolitica infection in a patient with hemachromatosis masquerading as proximal colon cancer with liver metastases: report of a case.

    A patient with genetic hemachromatosis presented with a clinical picture suggesting malignancy and CT evidence of lesions in the right colon and liver. colonoscopy failed to confirm the suspected diagnosis. Blood and stool cultures were positive for yersinia enterocolittica infection. This case illustrates the need to confirm clinically and radiologically suspected malignancy. It also serves as a model of how localized gastrointestinal pathology can result from the interaction of host genetic factors and specific microbial species. ( info)

33/218. Fatal yersinia enterocolitica biotype 4 serovar O:3 sepsis after red blood cell transfusion.

    BACKGROUND: Although posttransfusion bacterial sepsis is rare, this complication is associated with a high mortality rate. CASE REPORT: A fatal case of septic shock was observed in a 71-year-old patient following transfusion of contaminated red blood cells (RBCs) for refractory anemia. yersinia enterocolitica was isolated from the patient's blood sample and the transfused RBCs. Both strains were of bioserotype 4/O:3 and had the same NotI pulsotype. High titers of antibodies against Y. enterocolitica were detected in the donor's plasma sample 1 month after blood donation. The donor reported abdominal discomfort 3.5 months before blood collection but had no clinical signs of intestinal infection at the time of donation. CONCLUSION: Y. enterocolitica has been identified with increased frequency as a causative agent of posttransfusion septic shock. This nationwide investigation of these cases led to an estimated incidence of one case per 6.5 million RBC units distributed in france. Although rare, this often fatal complication remains nonpreventable worldwide owing to the lack of practical means for screening RBCs before transfusion. ( info)

34/218. Acute and chronic pancreatic disease associated with yersinia enterocolitica infection: a Norwegian 10-year follow-up study of 458 hospitalized patients.

    During the period 1974-1983, yersinia enterocolitica infection was diagnosed in 458 hospitalized patients by antibody response or isolation of the micro-organism. Eight (1.75%) patients showed signs of acute pancreatitis with elevated serum or urine levels of amylase; two patients had acute insulin-dependent diabetes. The patients were followed up for 4-14 years (until 1987). Four patients were readmitted with chronic pancreatitis, and one with acute pancreatitis. Diabetes developed in two males and nine females; in seven cases this was associated with chronic conditions of possible autoimmune aetiology. In 1987 a significantly higher than expected prevalence of diabetes was demonstrated among female subjects aged 30-54 years. yersinia enterocolitica infection constitutes a differential diagnosis in acute pancreatitis, and might be related to the development of chronic pancreatitis and diabetes. ( info)

35/218. Polyarteritis associated with yersinia enterocolitica infection.

    A patient developed polyarteritis, predominantly affecting the muscles, 10 days after a yersinia enterocolitica O:3 infection. Immunoperoxidase staining showed yersinia enterocolitica O:3 antigen in the subendothelial layer of the blood vessels. This suggests that vasculitis should be considered as a rare manifestation of yersinia enterocolitica infection. ( info)

36/218. Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease.

    A 39 year old woman presented with a short history of bloody diarrhoea. She subsequently developed microangiopathic haemolysis, platelet consumption, and renal impairment. Initial investigations suggested underlying Crohn's disease of the terminal ileum complicated by sepsis and disseminated intravascular coagulation. However, after resection of a perforated caecum and terminal ileum, the diagnosis of thrombotic thrombocytopenic purpura was made. There was weak serological evidence of yersinia infection, this may have caused the early localisation of the lesions to the terminal ileum. This is believed to be the first report of thrombotic thrombocytopenic purpura affecting the small bowel alone at presentation. ( info)

37/218. Multiple spleen and liver abscesses due to yersinia enterocolitica septicemia in a child with congenital sideroblastic anemia.

    In patients with iron overload, opportunistic infections are an underestimated risk. yersinia enterocolitica is a rare organism to be isolated in this setting. The authors report a case of disseminated Y. enterocolitica sepsis in a 5-year-old boy with sideroblastic anemia. Ultrasound examination revealed massive ascites, a pseudo-appendicitis, and hypoechogenic lesions corresponding to abscess formations in the liver and spleen. The initial antibiotic therapy consisted of cefotaxime, gentamicin, and metronidazole, but only treatment with ciprofloxacin and meropenem led to defervescence and clinical stabilization. The risk of developing uncommon infections in patients with iron overload should be acknowledged by all physicians, and the relevance of ultrasound examination is emphasized. In this case, only a detailed history revealed that several days before the onset of diarrhea, the child was feeding a deer; this is how infection was probably acquired. ( info)

38/218. intestinal obstruction complicating yersinia enterocolitica serotype O:21 infection in an infant.

    intestinal obstruction is an uncommon complication of yersinia enterocolitica infection. We report a case of enterocolitis in an 11-month-old infant, complicated by intestinal obstruction. Y. entercolitica serotype O:21, previously reported to cause severe disease, was isolated from the patient's stool. Unusual or complicated presentations of yersiniosis may be associated with more pathogenic strains of Y. enterocolitica. ( info)

39/218. Isolation of Yersinia-specific T cell clones from the synovial membrane and synovial fluid of a patient with reactive arthritis.

    synovial fluid (SF) mononuclear cells from patients with reactive arthritis (ReA) proliferate in vitro when challenged with ReA-associated bacteria, the maximal response being for the organism causing the triggering infection. We report the results of a study of the antigenic specificity of synovial T lymphocytes from an HLA-B27 positive ReA patient whose SF mononuclear cells responded preferentially to Yersinia antigens. This is the first report of the isolation of Yersinia-specific T cell clones from synovial membrane (obtained by closed-needle synovial biopsy). We present a detailed analysis of these clones, together with others obtained from the SF. ( info)

40/218. yersinia enterocolitica infection of a prosthetic knee joint.

    yersinia enterocolitica is a very common organism which is mainly associated with gastrointestinal symptoms. It has not previously been associated with early or late infection of a prosthetic joint replacement. We report a case of late infection, seven years after an uncomplicated knee replacement. This case demonstrates the ability of the organism to breach the joint capsule. There may well be an inherent under-diagnosis of Y. enterocolitica in infected prostheses due to the difficulty in the past of culturing the organism. ( info)
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