11/136. Immunological similarities between primary sclerosing cholangitis and chronic sclerosing sialadenitis: report of the overlapping of these two autoimmune diseases. Primary sclerosing cholangitis (PSC) is characterized by destructive inflammation and fibrosis affecting the bile ducts. The etiology of PSC is still unknown, although lymphocytic infiltration in the portal areas suggests an immune-mediated destruction of the bile ducts. patients with one autoimmune disease often suffer from one or more other autoimmune diseases. It is well known that there is a close relationship between PSC and inflammatory bowel disease, particularly ulcerative colitis(UC). However, the pathological findings in UC and other overlap diseases do not resemble those of PSC. In the present study, we report a patient with chronic sclerosing sialadenitis (Kuttner's tumor) and PSC. It is compared the sclerosing changes in both salivary glands and bile ducts histologically. In addition, the expression pattern of mast cell tryptase, b-FGF, and HLA-DR were examined in both tissues immunohistochemically. Histological features of sclerosing change in both salivary and bile ducts were quite similar. Marked mast cell infiltration and b-FGF expression were seen in the sclerosing areas in both tissues. In active inflammatory areas of the salivary glands, HLA-DR expression was also seen. We hypothesized that similar immune reactions occur in both the salivary gland and bile ducts and are responsible for the fibrosis that follows. ( info) |
12/136. Pneumoparotid: a case report and review of its pathogenesis, diagnosis, and management. Pneumoparotid is considered to be a rare entity, but the diagnosis might not be as uncommon as reported. We report a case in which computed tomography incidentally revealed air in the parotid ducts bilaterally. Treatment is aimed at the elimination of predisposing and causative factors, but because our patient denied any symptoms or precipitating factors and had a benign presentation, no immediate intervention was initiated. ( info) |
| Three cases of accessory parotid gland lesions are reported. The literature concerning accessory gland disease and its diagnosis and treatment is reviewed. ( info) |
14/136. Chronic sclerosing sialadenitis of the submandibular and parotid glands: a report of a case and review of the literature. Chronic sclerosing sialadenitis (also known as Kuttner tumor) is a chronic inflammatory condition of the salivary glands, first described by Kuttner in 1896. Clinically, the disease cannot be distinguished from a true neoplasm. The submandibular gland is affected more commonly than any other salivary gland. This report is of a case of widespread swelling of the salivary glands in which histologic features of chronic sclerosing sialadenitis were seen in the submandibular and parotid glands. The etiology, pathogenesis, and differential diagnosis of this disease and the clinical outcome of this case are discussed and presented. ( info) |
| Submandibular sialadenitis is exceptionally rare in neonates. We describe a case of submandibular sialadenitis progressing to submandibular abscess in a term neonate. The aetiology, investigations and treatment for this very rare condition are discussed. ( info) |
| AIMS : We report uncommon histopathological findings in fatal measles infection. methods AND RESULTS : We describe the autopsies of four patients who died during a measles outbreak in Sao Paulo, brazil, in 1997. Two of the patients were children receiving chemotherapy for non-Hodgkin's lymphoma, one was an adult with acquired immunodeficiency syndrome (AIDS) and the fourth was an apparently healthy woman. All patients had their deaths attributed to measles pneumonia. The autopsies revealed extensive giant cell pneumonia and diffuse alveolar damage, severe acute pancreatitis, necrotizing sialoadenitis and thyroiditis due to measles. measles antigen was detected in lung tissue using a monoclonal anti-measles antibody. CONCLUSIONS: : pancreatitis, thyroiditis and sialoadenitis are not previously reported histopathological findings in measles infection. pancreatitis is a potentially severe complication and should be considered when treating patients with atypical measles. ( info) |
17/136. Dramatic parotid uptake of I-131 on a diagnostic whole-body scan. radiation sialadenitis is a complication of I-131 therapy for thyroid cancer. They authors report a case of intense uptake by parotid glands in a diagnostic I-131 scan (2 mCi) in whom sialadenitis had developed previously after a 100-mCi dose of I-131. Similar examples of images could not be found in the literature. ( info) |
| lymphangioma or cystic hygroma is an uncommon benign congenital tumor of lymphatics that is seen in children and, rarely, adults. lymphangioma primarily involving the parotid gland is an extremely uncommon occurrence in adults. We report on the cytologic findings of a parotid lymphangioma in a 34-yr-old man which showed 13 cc of yellow fluid with red blood cells, lymphocytes, and rare fragments of benign-appearing salivary gland epithelium. The differential diagnosis of cystic parotid gland lesions in adults may include Warthin's tumor, lymphoma, benign lymphoepithelial lesions, branchial cleft cysts, chronic sialadenitis, cystic low-grade mucoepidermoid carcinoma, and cystic pleomorphic adenoma. In this case, the fine-needle aspiration findings along with the magnetic resonance imaging (MRI) findings of a multiloculated cystic mass in the parotid gland allowed the diagnosis of lymphangioma. ( info) |
19/136. submandibular gland sialolithiasis: a case report. Most cases of sialolithiasis of the submandibular duct are resolved by an intraoral surgical approach. This case is unique in that by virtue of the sialolith's proximity to the hilum of the gland, it was more prudent to perform an excision of the entire gland through an extraoral approach. ( info) |
20/136. Linear cutaneous lupus erythematosus in association with ipsilateral submandibular myoepithelial sialadenitis. We present the case of a young Caucasian female with a several years' history of left-sided submandibular gland sialadenitis in association with linear unilateral cutaneous lupus erythematosus apparently following the lines of Blaschko. The affected gland was excised and the cutaneous lupus erythematosus was improved considerably by oral dapsone. ( info) |