FAQ - Adenomatous Polyposis Coli
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Is it bad to have familial adenomatous polyposis at the age of 19?

It's bad at any age.  (+ info)

Does the mere finding of about 50 adenomatous polyps in my colon constitute a "polyposis syndrome" per se?

...or ar there other criteria that also need to be considered?
Does the causation - genetic versus sporadic - make a difference?
(I am currently awaiting "FAPKM" test results to try to learn more about the causation.

It certainly constitutes a problem and most likely some sort of a polyposis syndrome. To make an accurate diagnosis other things most definitely have to be taken into consideration. Familial polyposis usually has more than a hundred polyps. If it is less than 100, but you have a relative with FAP, it is likely FAP. It could also be attenuated FAP, if you have a relative diagnosed with colon cancer before the age of 55 who also had multiple polyps. There is also Gardner syndrome and Turcot syndrome. Patients with FAP are usually diagnosed by 30 and have polyps by 35. This diagnosis is not just putting you at a high risk for colon cancer, it is inevitable 95% have colon cancer by the time they are 50. Simply removing the polyps and changing your diet will not help this condition.

You and your doctors want to know exactly what you are dealing with. This information is important to your relatives as well. Get a second opinion and consider getting one from a teaching facility or a cancer hospital. You can find more information from the National Cancer Institute. I have included their link below. Best wishes.

http://www.cancer.gov/cancertopics/types/colon-and-rectal  (+ info)

Has anyone heard of FAP (Familial Adenomatous Polyposis) and has the disease..?

I have it, found out about 7 years ago, and had an ileo-rectal anastomosis, and need to go back in for another op or two and just wondering if there is anyone else who has this, or knows anyone, as the only people that I know that have this are my family. My hubby and I are planning another baby, but I has to much trouble with the first one (painwise) and wondering if hormones can speed up the growth of polyps? (hope this isn't to confusing... it's confusing me lol) Thanks = )

I know of FAP, it is a painful disorder because of risks but birth control, pregnancy hormones etc should not interfere with FAP, feel free to ask your doctor or your OB, good luck  (+ info)

Familial adenomatous polyposis - Is it transmissible?

Let me start off by saying that I am not calling my girlfriend a liar if it seems that way, I'm just a naturally curious person.

My girlfriend has Familial adenomatous polyposis (FAP) and almost a year ago she told me that because of this, if I were to somehow get some of her blood in my mouth (for example if I kissed cut), I would contract the disease through her DNA.
So here I am tonight, sitting at my computer, when I remembered my girlfriend mentioning it. With nothing to do, I decided to look it up and see if there are any other ways it can be transferred from person to person but I can't find any. I can't even find any mentions of it being transmissible through blood, so I'm pretty confused.

What is familial adenomatous polyposis?

Familial adenomatous polyposis (FAP) is an inherited disorder characterized by cancer of the large intestine (colon) and rectum. People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) growths (polyps) in the colon as early as their teenage years. Unless the colon is removed, these polyps will become malignant (cancerous). The average age at which an individual develops colon cancer in classic familial adenomatous polyposis is 39 years. Some people have a variant of the disorder, called attenuated familial adenomatous polyposis, in which polyp growth is delayed. The average age of colorectal cancer onset for attenuated familial adenomatous polyposis is 55 years.

In people with classic familial adenomatous polyposis, the number of polyps increases with age, and hundreds to thousands of polyps can develop in the colon. Also of particular significance are noncancerous growths called desmoid tumors. These fibrous tumors usually occur in the tissue covering the intestines and may be provoked by surgery to remove the colon. Desmoid tumors tend to recur after they are surgically removed. In both classic familial adenomatous polyposis and its attenuated variant, benign and malignant tumors are sometimes found in other places in the body, including the duodenum (a section of the small intestine), stomach, bones, skin, and other tissues. People who have colon polyps as well as growths outside the colon are sometimes described as having Gardner syndrome.

A milder type of familial adenomatous polyposis, called autosomal recessive familial adenomatous polyposis, has also been identified. People with the autosomal recessive type of this disorder have fewer polyps than those with the classic type. Fewer than 100 polyps typically develop, rather than hundreds or thousands. The autosomal recessive type of this disorder is caused by mutations in a different gene than the classic and attenuated types of familial adenomatous polyposis.

**I looked everywhere possible on the internet and found nothing that even hinted that this is transmissible. Maybe your girlfriend was misinformed on how it can be transmitted and was just worried about your safety. Let her know that you were just curious about her medical condition and that you did some research so you could be more informed of her situation and that you can't find anything stating that it can be transmitted. Tell her that she may want to speak with her doctor to find out for sure if it can be transmitted or if it is purely genetic.

Good luck!  (+ info)

Familial Adenomatous Polyposis/cancer question?

My boyfriend was diagnosed with Familial Adenomatous Polyposis (FAP) 2 years ago, 6 months after the diagnosis, cancer tumors attacked his colon - causing him to go through surgery to have half of it removed. He's been doing well since...until going into the hospital a week ago for relief from his kidney stones. Long, depressing story short.. the cancer is back, and this time attacking his liver & left kidney. Here's my question.. I'm trying to find someone who went through chemotherapy with a situation similiar to this. He is on the toss up of going through chemo because a lot of people he knows got really sick through chemo. And everytime I mention he could be saving his life by doing so, he throws up a wall & completely shuts down saying how everyone I know who has gone through chemo and is cancr free now, was in a completely different situation than he's in... which is true. He's getting second opinions from different doctors, but his first doctor that initially diagnosed the colon cancer before is highly suggesting chemotherapy...guess I'm just trying to do a little research online. Thanks.

He can locate other patients who have faced similar circumstances at online support groups . . many who post from all over the world. There are several strong support groups for colon cancer:

Colon Cancer Alliance

The Colon Club

ACOR: Colon Cancer Support online listserv

Good luck.  (+ info)

What are chances of my (future) children inheriting the condition Familial adenomatous polyposis?

My fiance was diagnosed with Familial adenomatous polyposis (FAP) when he was 23 years old. The FAP spread to his colon with resulted in cancerous polyps. He had surgery back in 2008 which removed his large intestines & part of his colon.

My question is this; Is there a medically correct percentage or number to which the chances if him & I conceived a child - that the child would be likely to have FAP? I understand that FAP is genetic, just wanted to know if there was a percentage that it COULD happen. Thank you.

Talk to this organisation, they are very helpful:  (+ info)

My son has been diagnosed with Juvenille Polyposis Coli..anyone have any info?

My son was recently diagnosed with jpd. He has had 13 polps removed from his colon thus far. None were cancerous, but they say that its inevitable before he turns twenty. Is anyone familiar with this disease?

Juvenile Polyposis

This rare, childhood-onset disease is an autosomal dominant disorder that results from mutations in various cancer susceptibility genes, including the SMAD4/DPC4 and BMPR1A genes. (this means that the gene can come from either the mother or the father as there are 22 gene pairs that are not sex specific)

The condition is associated with the development of hamartomatous polyps (few to numerous) that can be present throughout the gastrointestinal tract. Other symptoms can include diarrhea, hemorrhage, and protein-losing enteropathy.

Juvenile polyposis is associated with an increased chance for gastrointestinal and pancreatic cancers. Most patients appear to be sporadic cases (happening for the first time in a family). However, this may actually be the result of decreased penetrance (i.e., the causative gene mutation is present in one of the parents but the symptoms did not develop).
This site offers a group of resources, research and general information about Juvenile Polyposis and related diseases.
List of resources and research on Juvenile Polyposis
http://juvenilepolyposis.blogspot.com/2006/01/list-of-resources-and-research-on.html  (+ info)

What factors should drive treatment choices within the range of options to address adenomatous colon polyps?

There appears to be a range of discretion in the medical literature about treating a proliferation of precancerous ("adenomatous") colon polyps - from periodic surveillance colonoscopy with polectomy, to surgery to remove some or all of the colon? What are the factors and considerations a patient and doctor should consider in determining an appropriate course of treatment within this range of options?

What kind of medical literature are you reading?
I have no idea what a polectomy is, but there is no reason to remove part of the colon simply because you had polyps..  (+ info)

If there is a threatened e-coli breakout, why is is better to eat steak instead of a hamburger?

This is for my microbiology class and they are saying that if there was a threatened e-coli contantionation of meat that it is safer to eat steak instead of hamburger. But I don't know why this statement is true. Can anybody help me?

If properly cut, a steak has less of a possibility of contamination due to its location on the cow. Most cuts of steak come from the loin region of the cow, far away from the intestines of the animal.

Hamburger is bits and pieces of trim from several areas of the cow. Hamburger can contain regions that are not desired "cuts" of beef, or day-old steaks and parts.  (+ info)

Why are people so worried about E.Coli in their raw beef?

If the meat is throughly cooked, the threat from E.Coli is virtually zero.

The key word is "if". Far too many of our neighbors are too gol-darn knuckleheaded to listen, and when they don't cook their ground beef thoroughly and it does happen to be contaminated with E. coli, they will scream and swear and blame everyone but themselves when their small children lie in Intensive Care, dying from food poisoning their stupid parents caused.  (+ info)

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