FAQ - Bone Marrow Diseases
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Bone marrow..................?

Hey, when i turn 18 in a fuw months im going to put myself down on the Donation list.
I was just wandering, the people who need this cannot produce bone marrow right? So will the Bone marrow i Donate run out eventually and the person i donated to will need another Donation? Im not sure how it works? Could you tell me? What are the chances i will be able to Donate, as ive heard many people have put themselves down on the Donation waiting list for 15 years and haven't had a call to donate.
(Im Caucasian living in England if that makes any difference, as i heard its unlikely to find a match with another race?) Thank you.

Thank you.

Well, there are actually many different reasons to have a bone marrow transplant. I had leukemia, so my marrow did not function properly, and as the post above said, they used chemo and radiation to kill my marrow, gave me donor marrow, and now my marrow works the way it should.

I dont know a number on the odds, but yes, you may never get called to donate. Hematopoetic stem cells (which is actually what you are donating) are matched by HLA (human leukocyte antigen) tissue type, and that gets into dna testing and the tissue type is inherited. That is why its so hard to find a match and why, in this case, race matters. The best chance at a match is a full blooded sibling, and thats 1 in 4. The next best chance is a parent or child, and thats 1 in 8. After that, the chances of a person finding a match anywhere go way way way low, which is why the registry is so important. Your location isnt really that important. Even though each country has its own registry, most of them are searchable world wide.

Even if you never do get called to donate, being on this list in and of it self, allowing yourself to be included in the search for a match for thousands of patients is a HUGE thing, and as a transplant patient myself, I thank you for considering it.

If everything works the way its supposed to, the person receiving the transplant should remain healthy. However, sometimes people do need to have a second transplant, but I dont really know how often that happens. The transplant is phenomonally expensive. Most forms of insurance will only pay to have it done once, and its such a huge proceedure that many people wont do it a second time. After what I went through, I know that I am certainly not doing it again.  (+ info)

Why is a bone marrow transplant is sometimes used as a treatment for Leukemia?

Leukemia is a disease in which white blookd cells grow in an uncontrolled matter. Why is a bone marrow transplant is sometimes used as a treatment for this disease?


heres why:
because in a bone marrow transplant they first completely remove the persons bone marrow (the red bone marrow, not yellow) which is where the leukocytes (white blood cells) grow. Then they implant the new bone marrow that is healthy and not diseased that way healthy cells will grow.

does that help?:  (+ info)

What is the main function Bone Marrow has? Homework help?

Im doing a "Human diseases research assignment" for school. Im doing leukaemia so i need to know what the function Bone Marrow has in a healthy body? thanks for your help :)

There are two types of bone marrow: red marrow (consisting mainly of myeloid tissue) and yellow marrow (consisting mainly of fat cells). Red blood cells, platelets and most white blood cells arise in red marrow. Both types of bone marrow contain numerous blood vessels and capillaries.

At birth, all bone marrow is primarily purple. With age, more and more of it is converted to the yellow type. About half of the bone marrow is red. Red marrow is found mainly in the flat bones, such as the hip bone, breast bone, skull, ribs, vertebrae and shoulder blades, and in the cancellous ("spongy") material at the epiphyseal ends of the long bones such as the femur and humerus. Yellow marrow is found in the hollow interior of the middle portion of long bones.

In cases of severe blood loss, the body can convert yellow marrow back to red marrow to increase blood cell production.  (+ info)

What important function of bone becomes altered when the red bone marrow becomes afflicted with disease?

  (+ info)

What does it mean when you have no iron in your bone marrow?

Here is the kicker... I am NOT anemic..they test me all the time and iron in my blood (finger prick and blood test) is absolutely normal and not even close to low. I can't take iron pills they cause me to throw up intensely and give me horrible cramps. So no I am not on any kind of medication to help my blood iron level. Neither of my doctors can give me an explanation. So to summarize: How can you have no iron in your bone marrow but have normal iron levels in your blood??What does this mean? I don't mean to go on but I am diagnosed with Chronic Fatigue Syndrome, Osteoarthritis, possibly RA (got 1 test back positive waiting for results of 2nd), degenerative disk disease, diverticolitis, restless legs syndrome, my sed rate runs between 48-53(unknown inflammatory disease), and my WBC runs about 17. I am also under watch for Chronic Mylogeneous Leukemia, I DO NOT HAVE IT just under watch.Please Help!!!!!!!!!
I have already had a bone marrow test done. My oncologist/hematologist and GP and neurologist are all stumped by my situation. Under watch for CML means that with the way my bloodpanel and systems are going that I could possibly develop CML but the panels at this time are not where the have to be in order to actually diagnosed with it.

Since you can't take iron - try iron rich foods;

cream of wheat, apricots, molassas etc.

The RLS can sometimes be counteracted by more potassium IE banana but both could be sign of dehydration.

You might want to talk about a bone marrow biopsy - they hurt but then the docs can look at bone marrow cells and see if there is any problems.

Docs should rule out all the blood and marrow cancers also besides CML. Also look at liver panels

38 months and still here  (+ info)

What makes a bone marrow donor a match for a patient?

Is it blood type, DNA, iron count, etc.?
I'm writing a story that deals with bone marrow transplants and I need to know if a character could be a bone marrow match for another character.

It's down to genes unfortunately. Donor and recipient ideally should have the same human leukocyte antigens (a specific group of genes).  (+ info)

How painful is it to give bone marrow to someone that needs it?

I like to donate blood when I can, but now I am starting to consider donating bone marrow too. Is there anyone on here that has donated their bone marrow before and can you tell me how painful it was, and if you believe it was worth it?

Any detail will be helpful.


it hurts like hell but's it worth it to help a poor soul in need.  (+ info)

How long does bone marrow stay in the bones after an animal dies?

We had this substitute science teacher and he says he gets a science magazine or something or other and there was an article about the smithsonian museum and it said that there were some dinosaur fossils and they put them out on display and someone started smelling something funky and the scientists there cracked the bones open and there was still some bone marrow in there!

Your teacher was pulling your leg. Soft tissue protein has been found in bones, but only after chemical processing to uncover it. Right now people are still testing the material to make sure that it's really part of the original fossilized animal, and not the remains of bacteria that lived in the fossil.

You can real more about it here:
http://scienceblogs.com/notrocketscience/2009/04/dinosaur_proteins_cells_and_blood_vessels_recovered_from_brachylophosaurus.php  (+ info)

Can a bone marrow transplant save a terminally ill Lymphoma patient?

I'm curious for a friend. If a teenager is diagnosed with Non-Hodgkin's lymphoma and her case has been considered terminal, then a family member steps in and asks if they could do a bone marrow transplant, could she be saved?

Bone Marrow transplants are commen in lymphoma patients..

However, if the disease is considered terminal, it must have spread beyond the point where they feel they can stop it. Either that, or her body simply cant handle anymore chemo or radiation.

Dont ever give up hope though. There are records of thousands of people being told by doctors they were terminal and have gone on to survive and live long lives.  (+ info)

What is the difference between bone marrow biopsy and chromosome analysis?

Bone marrow revealed neutropenia and nurse said that they dont know what's causing it. Tested for every virus and negative. Waiting on chromosome analysis and what does that show?

"Lab Guy" has a superb answer.
C'mon Pedal7. You know these tests are completely different.
And you also know that it is impossible to test for every virus.
There are many hundreds of viruses. No one checks antibody levels for every one.
Relax and wait for the test results.
Be happy that no evidence of any type of leukemia was identified on the microscopic marrow examination.  (+ info)

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