FAQ - Bone Marrow Diseases
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What are the odds of surviving cancer after a bone marrow transplant?

My dad has non-hodgkins lymphoma and is going to a specialist because he has stopped responding to his chemotherapy. And they were looking into a bone marrow transplant.
Any information on it and the outcome would be welcome!

The odds are pretty good and getting better all the time. The best part is that even stage four lymphoma (some types) are now curable with stem cell or bone marrow transplants. Make sure you dad goes to a major cancer center that does lots of SCT or BMT and he should do just fine. He might have some lingering graft vs host disease but that sure beats stage four lymphoma.



http://www.marrow.org/PATIENT/Plan_Life_after_Tx/Managing_Long-Term_Effects_of_/Graft-Versus-Host_Disease/index.html  (+ info)

How late in Leukemia can a bone marrow transplant be helpful?

My dad has been told he has a year or less to live. I believe he said he is Stage III but could be IV. Is it too late for a bone marrow transplant to help him?

That is going to be dependent on a lot of things. What type of leukemia does he have? What other medical problems does he have? Has he already tried other treatment? Is this a relapse of first diagnosis?

As I said in the other post, not all of the hospitals in wv do the transplant... and honestly, not many hospitals in wv have the level of other treatment that other areas have. I would suggest that he at least gets a second opinion on his diagnosis and proposed treatment, and if possible an opinion from a facility that is bigger than wv has to offer.  (+ info)

Are there any religions against donating bone marrow or stem cells?

I need help finding any religions that are against donating/ receiving bone marrow or stem cells (not embryonic). I need ANY, even if they're a small religion. I also need credible sources where I can find information on them and site it. I do know that all major religions are ok with donating, but I need ANY that don't. Thanks.

Jehovah Witnesses do not believe in them or blood transfusions either.  (+ info)

why can't recipients of bone marrow transplants be under anesthesia during the transplant?

I have been told that a recipient of a bone marrow transplant can't be under anesthesia, but wasn't told why. And I can't find it anywhere. Does any one know?

I never heard of that, but no, we do not give anesthesia for this. I thought it was just a matter of getting an IV. The donors get anesthesia, though. Donating involves lots of punctures into your hip bones with a very big needle.  (+ info)

How do I find out if my family members are a match for bone marrow transplant?

Is there any way that my family members/friends can be tested to see if they are a match to my daughter who may, in the future, benefit from a bone marrow transplant, although she is not on a list to receive one at the moment?
Currently sufferers of her disorder are responding well to bone marrow transplants and I would like to know if anyone close to us is a good match in case this becomes a possibility.

You can, but you will likely have to pay out of pocket. Siblings have the best chance at being a match, 1 in 4. Parents or children have a 1 in 8 chance. Beyond that, its unlikely that a related donor would match.

You can have as many people tested as you want, but you will be paying out of pocket. The other thing to do would be to have these people sign up for the registry. If your daughter does go forward with a stem cell transplant (the medically correct term for the transplant), they will already be on the registry and will be a part of the search.

If you are in the us, you can sign up for the registry with the National Marrow Donor's Program at http://www.marrow.org They will explain where to go or how to do it by mail. It does cost a small fee to sign up for the registry, but it is much cheeper than paying for tissue typing out of pocket. It is quite expensive.

The site will also tell you how the transplant is done and the different sources of stem cells that can be used.  (+ info)

What happens when a bone marrow transplant is needed for chronic myeloid leukemia?

My mother may have chronic myeloid leukemia, and one of the ways of treating it is a bone marrow transplant.

Who are usually the closest matches for donors? Can children be a close enough match (usually) to be a donor?

Once a donor is found, what happens?

I am very worried, and would like to know what my chances are of being able to help my mother. I would like to know what may be in store for her, and how I can help her prepare in every way. I would also like to know how the transplant affects the donor so I may prepare, if I am a match.

Thanks for any help.

There is a non invasive way to treat CML (chronic myeloid leukemia). This is with the use of a drug called Gleevac (Imantinib). This drug targets the receptors on the CML cells and prevents them from dividing.

CML occurs as a result of a translocation of a chromosome to produce a new chromosome called the philedelphia chromosome and to produce a active protein called BCR/abl. This is a tyrosine kinase receptor which actively stimulates cells to divide uncontrollably. Gleevac targets the receptor specifically and stops the cell division.

Good luck!  (+ info)

What is involved in bone marrow donation? Can you sign up to donate it like organ donation?

I've got an NHS organ donation card on which I've signed up to give all my organs when I die bit I want to know if I can also sign up to donate my bone marrow somehow?
Whether it be that I donate it while I'm alive or when I die.

Hi Ellie,
You don't have to die to donate your bone marrow.

Contact the Anthony Nolan Trust for full details of bone marrow donation and to have your name put on a register of donors.

If, after contacting them, you want to go on the register they will arrange for you to have a blood sample taken. This is almost painless and is risk free.

The blood will be tested and your "tissue type" will be added to your details on the register.

If you are a match for someone with leukaemia, you will be invited to donate some bone marrow. This will be done at a time and place convenient for you and you can change your mind at any time.

I won't go into the details of how the bone marrow cells are taken because it would take ages to explain everything and, if you are not a match for anyone, you will not be asked to donate.

If you are asked to donate, everything will be explained to you. There may be a little discomfort but there is no pain as you will be given an anaesthetic during the procedure. As with any anaesthetic, there is a tiny risk involved but this is not great. You will spend a very short time in hospital but will be fully recovered in a couple of days.

You can change your mind at any time but, judging from your question, you are a very caring person and I'm sure you would think very carefully before raising someone's hopes of a possible cure for their leukaemia and then disappointing them at the last moment.  (+ info)

How do you get food sponsors for events such as bone marrow drives?

My family and a I are holding a bone marrow drive, and would like to offer anyone who shows up some food. Does anyone know how to go about getting donations from restaurants or grocery stores? Any suggestions are helpful.

Just approach medium-sized stores in your area, saying it is for charity and explain what it will involve. If they want recognition, you can always say the food is sponsored by them and promoter this fact on leaflets when advertising the drive or on plates serving the food.

It's a win-win situation. Smaller companies might not be able to afford to do this, but medium-sized ones are often happy to help in return for a bit of promotion. Good luck, hope it goes well.  (+ info)

How much does it hurt to get bone marrow taken out of your sternum?

I'm getting a procdure done that requires my bone marrow to be take out of my sternum. Local anestesia will be used. How much does it hurt? Will it be sore? Will her be a scar? What should I expect? Is it better just to be put under?

A friend had a bone marrow biopsy of the hip last week.
Everytime you start to feel something , ask for more freezing.
They refreezed her about 7 times. On a scale of 1 to 10 with 10 being the worst pain, she said it was a one.
Good luck , you will be fine.  (+ info)

What are the odds of being a bone marrow match?

After being on the bone marrow donor list for 20 years, I was contacted as being a match. Was just wondering what the chances were of being an unrelated match.
After being on the bone marrow donor list for 20 years, I was contacted as being a match. Was just wondering what the chances were of being an unrelated (not related to the reciepient) match.

I was contacted once too, but after further testing, they determined I wasn't a good match. I'm not sure what the numbers are, but I think the chances are pretty low that you'll match.  (+ info)

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