FAQ - Cervical Intraepithelial Neoplasia
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Is CIN 2 (Cervical intraepithelial neoplasia) Really that serious?

I know a girl who was just diagnosed with it, and it sounds like she is exaggerating a bit. She has to have a LEEP done and is convinced that she will never have kids again. I read up on it and from what I read, it says that maintaining a pregnancy can be difficult but not impossible.

Is it really that bad?

I had CIN 2 when I was 20. My Dr. showed me what a healthy cervix looked like and what one with CIN2 looked like - it's not pretty. My Dr. pretty much said that if I didn't have it treated it would of led to cancer within 7 years. I had Laser done, and have had normal paps ever since and I make sure to get them done on a yearly basis.

I went on to have two wonderful healthy kids years later.

Your friend will be fine - she is aware and having it treated which makes all the difference. CIN3 is pretty much cancer, so she at least has caught it before it got any worse. She probably is very scared and thinking the absolute worst. Tell her my story - that might give her some positive thoughts in having future children. Her Dr. should be able to go over her fears with her too. I had a great Dr. and he told me from the start that this didn't mean I wouldn't be able to have children - he was right.  (+ info)


Cervical Dysplasia

Cervical dysplasia is the abnormal growth of the epithelial tissue on the surface of the cervix. It refers to a spectrum or continuum of changes specified as: CIN I -- mild dysplasia; CIN II -- moderate to marked dysplasia; and CIN III -- severe dysplasia to carcinoma-in-situ (cancer localized to the intraepithelial tissue/superficial layer of the cervix).
While the cause is unknown, a number of predisposing factors have been identified. Less than 5% of all Pap smear tests conducted note cervical dysplasia. It may occur in women aged 15 and older, with the peak incidence in women aged 25 to 35.
Increased risk is associated with: multiple sexual partners, early onset of sexual activity (at less than age 18), early childbearing (at less than age 16), and past medical history of DES exposure or sexually transmitted diseases, especially HPV (genital warts), genital herpes, or HIV infection.  (+ info)

Cervical Intraepithelial neoplasia does anyone knows?

what genes are related to this?

CIN is most commonly associated with human papilloma virus (HPV) infection--most commonly HPV 16/18. HPV produces two important proteins that mess with your cell cycle control: E6 binds and inactivates p53; E7 binds Rb. Inactivation of tumor suppressor proteins (p53, RB) leads to uncontrolled cell division. When the proliferation is within the basement membrane, it's considered "Intraepithelial". CIN is graded on a I-IV scale, depending on the thickness of the epithelium involved.  (+ info)

is cervical intraepithelial neoplasia malignant or benign?

Cervical intraepithelial neoplasia, or CIN, is the abnormal growth of precancerous cells in the cervix. Most cases of CIN stay the same or are eliminated by the host's immune system without intervention, but a small percentage of cases progress to become cervical cancer, usually cervical squamous cell carcinoma. The major cause of CIN is infection with the sexually transmitted human papillomavirus.  (+ info)

cervical intraepithelial neoplasia 1 or (CIN 1)?

i've read a lot of research about CIN1 and one states that CIN 1 will regress naturally without treatment. can i know how accurate is this?and is there any treatment of CIN 1 WITHOUT TOUCHING THE CERVIX?

CIN 1 resolves in about 4 out of 5 women. The problem is nobody can identify which women will progress and which won't. You could try seeing a properly qualified naturopath to learn how to improve your immunity and fight it naturally, but I would still recommend you let your OB-GYN keep an eye on it and continue with regular smears.  (+ info)

vagial intraepithelial neoplasia (VIN type 1)?

I've been diagnosis with vagial intraepithelial neoplasia (VIN type 1) it came back twice. Has anyone had this, will it turn into cancer later.

Vaginal Intrapethelial Neoplasia I (VAIN) is the very first stage of vaginal dysplasia, it is very mild, so you caught it early which is great. I have VAIN too, (unsure what stage) but the doctor said I would be looking at surgery soon, so I am guessing a biopsy is coming soon too! OUCH. I also have VIN which is vulvar dysplasia.

Since this is the second time you have had VAIN pop up and you are under the care of a doctor I doubt very seriously that it could spread to invasive cancer unnoticed. I am assuming your doctor has you on a "watch & wait" plan, a check-up every 3-6 months, so chances are if it gets worse he will treat it. VAIN, which is caused from HPV is very slow growing and rarely goes invasive. I hope this calms your fears a little. I help run a support group for women with VAIN, VIN, and CIN if you are interested, we would love to have you. No one should go this alone.  (+ info)

Histopathology report diag "cervical intra epithelial neoplasia 1to2"please advise.?

My wife's medical report of dept.of histopathology shows diagnosis above coment.Doctor advises for total abdominal hyste.We want to know if there will be any post operation effect on her.She is now 37years old.

This is CIN 1 or 2.

It is NOT cancer!!!!!!!

But a pre-cancerous change in the cells trhat line the uteriuse.

CIN 1 and 2 is very low grade.
And can still 'become' normal again.

Your wife's Doctor is jumping the gun.
What is he up to?
Hell. they only advise this type of radical surgery at her age if it is positively cancer not pre-cancerous.
She would become medopausal from removal of her ovaries.
And abdominal hyster is now very rare as they remove the uteruise through the vagina.


I had Advanced CIN 4 with cancer cells in the outer layer of the uteruise and NEVER had a hysterectomy as the first treatment!

E-mail me through my profile if you or your wife would like to talk.  (+ info)

Does anyone know the Bethesda classification for CIN (cervical intraepitheliak neoplasia)?

I've tried searching for it at google, medline, and medscape with no luck.

Give Yahoo a try - these are only a couple of the links I found.

Have you tried Web MD?  (+ info)

What is Low Grade Squamous Intraepithelial Lesion?

The doctor told me i have Low Grade Squamous Intraepithelial Lesion i was just wondering what this meant but in easier terms... I don't quite understand how they are wording it over the internet it's confusing to understand? Thanks!

You already know you should have asked your doctor to explain in simpler terms. Make a habit of this in the weeks to come. I'll try to explain what a low grade squamous intraepithelial lesion, or LSIL, is for you in terms you should easily be able to understand.

An LSIL is a type of abnormal growth of squamous cells on the surface of the cervix. Squamous cells are a flat, scale-like type of epithelial cell. Epithelial cells are cells that help absorb, move, and distribute some of the fluids and nutrients in the body. Epithelial cells form epithelial tissue and this tissue, called epithelium, forms the covering of most internal surfaces and organs as well as the outer surface of our body. It forms and lines the vagina and uterus. The cervix is the "neck" of the uterus, the opening at the base of the uterus into the vagina. (ep-ih-THEE-lee-ul, INTRA-ep-ih-THEE-lee-ul, ep-ih-THEE-lee-um, SQUAY-muss)

There are low grade squamous intraepithelial lesions and high grade squamous intraepithelial lesions. The terms "low grade" and "high grade" (in reference to squamous intraepithelial lesions) refer to how abnormal the cells are and how much of the cervix is affected. A low grade squamous intraepithelial lesion is one in which the cells are not very abnormal and not much of the cervix is affected.

An LSIL does not mean you have cervical cancer or will have cancer but because they CAN progress to cancer, because they have the potential to become malignant, they should be treated early. Was I able to make this clearer for you?  (+ info)

What is cervical mucus like on the day of ovulation?

I've heard that you get egg white cervical mucus 3-4 days BEFORE ovulation actually occurs?

I got an abundance of egg white cervical mucus on cycle days 13 & 14 and now the last two days it hasnt been there.

But according to that theory does that mean I'll ovulate on cd 16 or 17? Something like that.

How soon after experiencing your peak amount of egg white cervical mucus will you ovulate?

this is one i am wondering i started getting stringy c/m wed by friday it was ewcm when i got up in middle of night to feed bub i was watery (tmi) but anyway not much sat , sun morn very + opk sun evening o pains , but today no c/m so it must be befor ovulation in my case   (+ info)

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