FAQ - Diphtheria
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What is the classification (Genus Species) and Defense (specific and nonspecific) of Diphtheria

genus Corynebacterium - the type genus of the family Corynebacteriaceae which is widely distributed in nature; the best known are parasites and pathogens of humans and domestic animals
bacteria genus - a genus of bacteria Corynebacteriaceae, family Corynebacteriaceae - a large family of mostly Gram-positive and aerobic and nonmotile rod-shaped bacteria order Eubacteriales
corynebacterium - any species of the genus Corynebacterium
C. diphtheriae,
Corynebacterium diphtheriae,
Klebs-Loeffler bacillus - a species of bacterium that causes diphtheria

In general, specific acquired immunity to human pathogens is directed to only one or a few protective antigens. The immunologic properties of the protective antigen are important determinants of the human protective defense

Diphtheria toxin catalyzes the ADP-ribosylation of, and inactivates, the elongation factor eEF-2.[6] In this way, it acts to inhibit translation during eukaryotic protein synthesis  (+ info)

How important is immunising against tetanus, diphtheria and polio at the age of 14?

Im 14 and just got a letter through the school for tetanus, diphtheria and polio immunisation...
Im really doubtful about this kind of thing (I hardly ever believe things first time explained etc)

Are all 3 diseases, separate vaccination needles?
Is it 100% necessary to have them done?

Im told the side effects are only swelling, redness tenderness on the injection spot. Sometimes fever headache dizziness and swollen glands. Is this all? Is there anything I have not been told?

thanks in advance

It is called the DPT vaccine and it is very important. It is only one vaccine, so no worries there. You just need a booster, you have already had the vaccine once. This particular vaccine only helps for about 10 years. It is probably one of the safer vaccines you will ever get.

Let me tell you about what can happen if you don't get the vaccine. First, Tetanus... It can cause lockjaw, irregular heartbeat, and muscle contractions. Look up pictures on google image search. You won't like what you see.

The P in DPT actually stands for pertussis: it is also known as whooping cough. It can cause a horrible cough that you will have for a long time.

D is diphtheria is kind of like a cold, but much much worse. It can make your entire neck swollen and you can suffocate. Totally not cool

You may actually need the polio immunization, but you should have gotten that before school. If not it can actually be a nasal spray I believe. More than likely though, you just need the DPT vaccine.  (+ info)

Is Diphtheria and Tetanus an all in one injection?

Im 14 years old. I have to my jabs next week. I was wondering if DIPHTHERIA and TETANUS is an all in one injection? Is POLIO a liquid when they put in the mouth or is it mixed with DIPHTHERIA and TETANUS injection?

depends on where you have it, most are diptheria and tetanus and some also contain polio it lasts for 10 yrs

polio is also given as a liquid in the mouth but its horrid - tastes like sweaty socks  (+ info)

should my arm hurt after Diphtheria and Tetanus vaccines?

I got a Diphtheria and Tetanus vaccine yesterday and my arm is starting to hurt more and more. I can barely lift my arm now. Is that normal? what could be the reason?

The reason your arm hurts is because your healthcare provider just injected a toxic solution into your muscle tissue, bypassing the blood-brain barrier that is the body's first defense against foreign toxic invaders. You really should have done some investigation into the ingredients that were in those vaccines before you took them. But here they are: Diptheria and Tetanus vaccine (DTaP) includes some or all of the following ingredients...Formeldahyde (used to enbalm deceased people), Aluminum Hydroxide (adjuvant which is likely causing your pain..Implicated as a cause of brain damage; suspected factor in Alzheimer's Disease, dementia, convulsions and comas.), Gelatin (contains Aspartame), Polysorbate 80 (causes infertility in female lab mice), Thimerosol (contains Mecury, one of the most toxic substances to humans), 2 - Phenoxyethanol (Used as an insect repellent, Classed as "Very Toxic Material". May lead to kidney, liver, blood and central nervous system (CNS) disorders), Streptomycin (An antibiotic), Aluminum phosphate (another adjuvant), Polymyxin B (an antibiotic), Bovine (cow) serum, Hydrochloric acid, Glycine and some others.

Read down to CONCLUSIONS of the following:

Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.

Rennels MB, Deloria MA, Pichichero ME, Losonsky GA, Englund JA, Meade BD, Anderson EL, Steinhoff MC, Edwards KM.

University of Maryland School of Medicine, Baltimore, Maryland, USA. [email protected]

BACKGROUND: Diphtheria and tetanus toxoid combined with acellular pertussis (DTaP) vaccines are less reactogenic than diphtheria and tetanus toxoid combined with whole cell pertussis (DTwP) vaccines. However, local reactions increase in rate and severity with each successive DTaP dose, and swelling of the entire injected limb has been reported after booster doses. METHODS: We reviewed reports of swelling of the entire thigh or upper arm after the fourth and fifth dose, respectively, of DTaP vaccines administered in the National Institutes of Health multicenter comparative DTaP studies. Relationships were explored among reports of severe swelling, rates of other reactions, quantity of vaccine contents, and prevaccination and postvaccination antibody levels to pertussis toxin, tetanus toxin, and diphtheria toxin. RESULTS: Entire thigh swelling was an unsolicited reaction reported in 20 (2%) of the 1015 children who received 4 consecutive doses of the same DTaP vaccine. The reaction was associated with 9 of the 12 DTaP vaccines evaluated. Although there were no reports of swelling of the entire upper arm in 121 children given a fifth dose of the same DTaP, 4 (2.7%) of 146 recipients of 5 doses of a mixed schedule of DTaP vaccines experienced such swelling. Rates of other reactions were higher in children with entire thigh swelling than in those without. Of the children with entire thigh swelling, 60% had local pain, and 60% had erythema. All swelling subsided spontaneously without sequelae. There was a significant linear association between the rates of entire thigh swelling after dose 4 and diphtheria toxoid content in the DTaP products. Lesser degrees of swelling (>50 mm but less than entire limb) correlated with pertussis toxoid content after dose 4 and aluminum content after dose 5. No relationship was established between levels of serum antibody to diphtheria, tetanus, or pertussis toxin and rates of swelling of the whole thigh. CONCLUSIONS: Booster doses of DTaP vaccines can cause entire limb swelling, which is usually associated with redness and pain. Our data suggest that this extensive swelling reaction may be more common with vaccines containing high diphtheria toxoid content.  (+ info)

Smoking Weed right after getting a Diphtheria shot?

I was preparing on smoking weed tomorrow with a friend, but also have an appointment to get a "Diphtheria" vaccine/shot from my doctor. My question is, Is it safe to smoke a joint after getting said vaccine? Within the hour?

Not within the hour, because an unknown complication may arise, just tell your buddy to hold off until afternoon cartoons start!!  (+ info)

Any good sites for researching diphtheria?

I need to know how the bacterium itself actually attacks the immune system. A website would be most helpful, but if you actually know how it works, you could just write it here.

The article associated with this link has a lot of information on the disease. I hope it's what you're looking or.

http://www.healthline.com/adamcontent/diphtheria?utm_medium=ask&utm_source=smart&utm_campaign=article&utm_term=Diphtheria&ask_return=Diphtheria  (+ info)

can you drink alcohol after having the tetnus and polio and diphtheria jab the same day ?

today i had the tetnus polio and diphtheria jab and i want to have a little drink would that be ok to drink today ?

  (+ info)

What would happen if the vaccination programme for diphtheria was cancelled?

If the vaccination program for diphtheria was halted, we would see a resurgence of the disease. Corynebacterium diptheriae is the causative organism (a bacteria) of diphtheria which affects mostly young people. Before the advent of vaccination, an estimated 15,000 people died every year in the U.S. After the vaccination program was implemented, the fatalities dropped to less than one every year.  (+ info)

How did diphtheria start?

What is the infectious agent that causes diphtheria?
Diphtheria is caused by Corynebacterium diphtheriae, a bacterium. The bacterium produces a toxin (poison) that is carried in the bloodstream.

Where is diphtheria found?
Diphtheria is common in many parts of the world. Diphtheria bacteria live in the mouth, nose, throat, or skin of infected persons.

How do people get diphtheria?
Diphtheria spreads from person to person very easily. People get diphtheria by breathing in diphtheria bacteria after an infected person has coughed or sneezed. People also get diphtheria from close contact with discharges from an infected person's mouth, nose, throat, or skin.

What are the signs and symptoms of diphtheria?
Usually, diphtheria develops in the throat. Early symptoms are a sore throat and mild fever. A membrane that forms over the throat and tonsils can make it hard to swallow. The infection also causes the lymph glands and tissue on both sides of the neck to swell to an unusually large size.

Some people can be infected but not appear ill. They can also spread the infection.  (+ info)

From where do people get diphtheria?

I tried searching on google, but all I get are links that say you get it from another infected person. How does that first person get it before passing it around? Is it from food? Garbage? What?

Good question.
Like any disease caused by bacteria, the inital human infection is widely unknown. Bacteria tend to evolve rapidly and it is unknown when certain bacteria develop the mechanisms needed to cause human infection. In this case the infection originated from human exposure to the bacillus C. diphtheriae or C ulcerans bacterium. As you properly know bacteria are everywhere and we are exposed to them everyday, even the keyboard you are touching containing millions of them, properly more.
In order for someone to develop diphtheria, they need to inhale the bacteria so it enters there sinuses, during which the bacteria breed, release an endotoxin and cause a potentially life threatening disease, diphtheria. Diphtheria is transmitted by droplet infection through contact with a patient or carrier, or rarely articles soiled with discharges from infected lesions. Asymptomatic carriage can occur (up to 5% of people in endemic regions) but is extremely rare in developed countries. The probability of spread depends on the closeness and duration of contact. Prolonged contact (eg sleeping in the same room as a case rather than casual contact) is usually required.

Are you asking where the Corynebacterium diphtheriae bacteria are present when they are not living in a person's sinuses?
Corynebacterium diphtheriae bacteria are mainly present in the spring and winter months and Human carriers are the main reservoir of infection. so basically you can get them from "human carriers" of the disease, people who harbour the bacteria but don't get infected by them.
They are also linked to zoonotic transmission to humans and has been most frequently seen in agricultural communities associated with livestock, so you can get them from some infected farm animals, particularly livestock.

When wanting to find such info. in a search engine about a particular disease, firstly find the bacteria's name that cuases the infection and search for its Pathophysiology. It should give you the answers that you need.  (+ info)

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