FAQ - Exocrine Pancreatic Insufficiency
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My Dog Has Exocrine Pancreatic Insufficiency?

The vet has said our german shepherd dog has to have enzyme capsules and suggests Hills id dog food. Has anybody had a dog with the same condition? Did your dog do well with the above treatment?

I have not had a dog with the same condition, but this might help. You may want to readjust the dog's diet, including more vegetable foods, and less of that overly processed, unhealthy dog food. Perhaps also give him some of the food you eat if it is healthy. It sounds like your vet is a good businessmen rather than a perceptive judge of your dog's health. I would skip the pricey pills. Try omega 3 tablets, the same ones given to humans.  (+ info)

Exocrine pancreatic insufficiency can this be common in rottweilers?

Ive not heard of it in Rotties b4. AND i have a Rottie today, & am always checking for signs.

In my experience, (my white GSD had this) the numerous vets I saw over the 5 year period said it was common in German Shepherds & more in bitches too. (She was put to sleep after deteriorating in June 2004 bless her.)

If your Rottie has it, I sympathise with u entirely. Its a hard condition to live with in a dog...especially around children.  (+ info)

What are some conditions causing Pancreatic Insufficiency?

In a 3 year old, with severe asthma, weight loss, leg and arm pain, NEGATIVE sweat tests and lot of other symptoms?

Anything other than CF or Shwachman Syndrome that you can think ?of?

Pancreatic insufficiency is the inability of the exocrine pancreas to produce and/or transport enough digestive enzymes to break down food in the intestine and to allow its absorption. It typically occurs as a result of progressive pancreatic damage that may be caused by recurrent acute pancreatitis or by chronic pancreatitis due to a variety of conditions. In children, for example, it is most frequently associated with cystic fibrosis (CF). Shwachman-Diamond Syndrome (SDS) is the second most common cause of inherited pancreatic insufficiency after CF. All patients with SDS have some degree of pancreatic insufficiency beginning in infancy. Pancreatic insufficiency can also be associated with type 1 or autoimmune diabetes. It is less frequently but sometimes associated with pancreatic cancer.
Pancreatic insufficiency usually presents with symptoms of malabsorption, malnutrition, vitamin deficiencies, and weight loss (or inability to gain weight in children) and is often associated with steatorrhea (loose, fatty, foul-smelling stools). Diabetes may also be present in adults with pancreatic insufficiency  (+ info)

Does diabetes also cause (mild) pancreatic insufficiency?

The reason I am asking is because it is said that the likelihood of someone having type TWO diabetes goes up if they tend to gain fat along the waistline and tummy.

Accumulation of fat along the waistline in is associated with lack of digestive enzymes, particularly amylase, which digests carbohydrates and is produced by the pancreas.

Strangely enough though, type two diabetes has been stated to have little to do with insulin insufficiency. But accumulating fat along the waistline does seem as an indicator of both diabetes type two AND pancreatic insufficiency.

Does any one know the CAUSE that people with type TWO diabetes tend to accumulate fat along the waistline??? Does the production of amylase have anything to do with it???

Has anyone tried to treat diabetes by simply taking amylase supplements???

Actually, I have discovered somewhat the opposite. Amylase digest carbohydrates(sugars) where they are absorbed into the blood. The pancreas secretes insulin to lower blood sugar, most of the the time disproportionately to the amount of sugar. If the sugar is not used ( through some type of physical activity) it is turned into a triglyceride and eventually stored as fat. The absence of amylase would not allow the digestion of carbs thus blood sugar does not rise. Its the bases behind the dietary supplement called carb blockers. Its active ingredient is white kidney bean extract that block the enzyme amylase that digest carbs.

Hyperinsulinity from a diet heavy in simple carbs is the main mechanism for excessive fat storage.

I would postulate that amylase supplement would actually increase your blood sugar and increase fat storage.

Good luck.  (+ info)

VERY STRANGE Fecal Elastase results. Pancreatic insufficiency?

My son (3.5 years old) had an endoscopy and it showed that his Lipase was 0!!! and his Amylase was about 2/3 of what it should at least be. HOWEVER, they wanted to do a fecal elastase to determine what kind of enzymes and how much to give him and it CAME BACK NORMAL....

Does this mean that one of the tests HAVE to be WRONG? or is there something that can cause this.

Not necessarily. You don't say why he needed the tests, but children with cystic fibrosis have to take enzymes for pancreatic insufficiency and they don't all have exactly the same doses, so the impairment in pancreatic function varies from child to child.  (+ info)

my dog has pancreatic insufficiency?

my dog has been diagnosed with pancreatic insufficency this problem is life long and the drugs are really expensive she is insured so at the moment its not a problem but what am I to do when I reach the amount they will pay out stops,

My dog has the same, he was dx at 3 he's now 11. Tryplase and Pancrex used to be prescription only but you can now buy it on the internet w/o prescription. Try www.vetmedic.co.uk. We now use Lypex which is half the price of Pancrex, costs us about £35 per month as opposed to £58. The amount you will use will obviously depend on the size/weight of your dog, the condition can also fluctuate ie. sometimes they may be producing enough enzyme to digest their food w/o needing a full dose, but time will tell you how much is the correct dose. I'm afraid the answer really is that the dog will literally starve to death without the enzymes. Your vet may be able to help with costs, as you say it is a lifelong condition and you will be a regular customer.

It's heartbreaking to see your dog with this condition and you obviously want the best. If it is going to be too expensive for you perhaps rehoming could be an option? although that wouldn't be easy. You find a way, that's all I can say really! so many people told us to have our Reg put to sleep, we couldn't and wouldn't do it. What kind of dog is he/she? it's more common in larger breeds such as German Shepherds, which is what Reg is. Good luck to both of you, internet search is your best bet to source the medicine cheaper and they are a lot more reliable than sites for human drugs! we didn't have ins. for Reg as we were overseas and they wouldn't pay - that is 8 years ago though, it cost more than £1000 to get him diagnosed his weight during the diagnosis process plummeted from 42k to 18k, it really is a hideous condition.  (+ info)

How do chemotherapy drugs affect the exocrine system?

Hi I need to know how chemotherapy drugs affect the exocrine system. And the side affects caused by them on the exocrine system.

Same answer as you other question. This must be school work.
As I wrote there are over 100 drugs that are called "chemotherapy."
Each chemotherapy drug is different.
Each has a different side effect profile.
You would need to look up - do an internet search for - "Chemotherapy drugs"
- and then look into each one individually.
http://www.chemocare.com/BIO/  (+ info)

Why is the pancreas considered both an endocrine gland and exocrine gland?

what would an example of it's endocrine function and it's exocrine function?

Endocrine because it releases products in to the bloodstreams (such as insulin, somatostatin and glucagon)
Exocrine because it also releases some products in to ducts (like digestive enzymes are released in to the small intestine via a ducts)  (+ info)

What make pancreatic cancer so different from other cancers?

From everything that I have read about pancreatic cancer it is uncurable. Breast cancer, leukemia, and other kinds of cancer can be cured/brought into remission and I was wondering what is so different about pancreatic cancer that does not allow this type of cancer to be cured/go into remission?

Pancreatic cancer can be treated for cure under very specific conditions. It spreads by local invasion and via lymphatic channels. If it is caught early prior to invasion in the local vasculature, it can be treated for cure via several procedures - Whipple (pancreaticoduodenectomy), Total Pancreatectomy, or Distal Pancreatectomy. A major issue is catching it early. The symptoms of this disease early on are usually no symptoms, vague abdominal pain, mild discomfort. It is hard to detect. There is also no good screening that is cost effective. The reason for this is the cancer is not that common, and the tests available are not that cheap. This makes for a very inefficient screening method. The ones out there currently that can detect pancreatic cancer include CT scan of the abdomen and Endoscopic Ultrasound. Both of these tests have their own drawbacks. CT scan of the abdomen involves radiation that may set you up for a cancer. Endoscopic ultrasound requires sedation, a specialist (gastroenterologist), and has risks of perforation. Also the tests need to have a high degree of sensitivity (meaning that there is a high number of people who have the disease also test positive). Endoscopic ultrasound is being used more for symptomatic pancreatic cancer, but I do not know of studies used for screening the general population.

Another issue is it's proximity to other organs. It is near the duodenum, stomach, inferior vena cava, aorta. It is also a part of the biliary system and liver. It can spread to many important organs easily.

There is some increased hope on the horizon as new chemotherapy drugs are being developed. Dr. Vickers at the University of Minnesota is doing clinical trials on a new medication that will hopefully help with treating the disease.  (+ info)

What do you need to be aware of when diagnosed with adrenal insufficiency?

I was told I have adrenal insufficiency and looked on line about what this means as far as how it will affect the rest of my life. I have read you need to wear an alert bracelet (for what?) and other things.

Well if you read up on it you know that improperly treated, it could become a life or death situation if you were in an accident and unable to speak. Your medic alert will tell them of your condition, then they can in tern, contact your Dr and they will be able to find out what they need to do for you. I know, I wear a medic alert. If I didn't and I was in that situation, the first med they would give me for pain would kill me. It's a common pain medication and used at accident sites. For me, it's a death sentence. So you have your Dr. phone # on there as well as your physical problem. They can save your life. So get one. Adrenal insufficiency is a serious problem. Good luck  (+ info)

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