FAQ - Leishmaniasis, Mucocutaneous
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Does any one know a treatment for Leishmaniasis?


I worked as a DOD contractor for 13 months in IRAQ. Both of my forearms have sores that appear for several weeks then go away then return again. They are from my wrist to my elbow, the only part of me that was not covered.I am sure it is
Leishmaniasis from the sand fly bites I got. Does anyone know a treatment for Leishmaniasis? I have no insurance and can't seem to find any help.
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If it's Leishmaniasis, you really should have it properly diagnosed. The treatment can include pentavalent antimonials (sodium stibogluconate), and if systemic amphotericin B.

However, the latter is quite nephrotoxic (toxic to kidneys) and both have significant side effects. If its only cutaneous Leishmaniasis, often it's left alone and heals itself over months.

Again, you need to be sure its Leishmaniasis before you start thinking about any treatment. Go to an army medical facility if you can. They are familiar with these diseases, and will be able to take biopsies of the lesions to test for evidence of parasites. Especially since many US troops in Iraq have gotten Leishmaniasis, so they will know how to handle it.

The meds are not ones that you can just pick up and take, they're given with IV.

Hope this helps.  (+ info)

Why leishmaniasis is transmitted by sand flies bite? Why not by other mosquitoes?


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i recently went to houndourous and got 63 san fly bites what are the chances i will contract leishmaniasis?


the chances are still not very high, the majority of flies do not carry the leishmaniasis pathogenic infectious diseases causing bacterium, and getting bitten from only 63 does not raise your chances very much, if you are having no symptoms yet, there is most likely a 2.39% chance that you have contracted this disease.  (+ info)

What is the cure for leishmaniasis?


Is it cureable, how do you find a compentent physician
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From wiki:
There are two common therapies containing antimony (known as pentavalent antimonials), meglumine antimoniate (Glucantim®) and sodium stibogluconate (Pentostam®). It is not completely understood how these drugs act against the parasite; they may disrupt its energy production or trypanothione metabolism. Unfortunately, in many parts of the world, the parasite has become resistant to antimony and for visceral or mucocutaneous leishmaniasis,[2] but the level of resistance varies according to species.[3] Amphotericin is now the treatment of choice[4]; failure of AmBisome® to treat visceral leishmaniasis (Leishmania donovani) has been reported in Sudan,[5] but this failure may be related to host factors such as co-infection with HIV or tuberculosis rather than parasite resistance.

Miltefosine (Impavido®), is a new drug for visceral and cutaneous leishmaniasis. The cure rate of miltefosine in phase III clinical trials is 95%; Studies in Ethiopia show that is also effective in Africa. In HIV immunosuppressed people who are coinfected with leishmaniasis it has shown that even in resistant cases 2/3 of the people responded to this new treatment. Clinical trials in Colombia showed a high efficacy for cutaneous leishmaniasis. In mucocutaneous cases caused by L.brasiliensis it has shown to be more effective than other drugs. Miltefosine received approval by the Indian regulatory authorities in 2002 and in Germany in 2004. In 2005 it received the first approval for cutaneous leishmaniasis in Colombia. Miltefosine is also currently being investigated as treatment for mucocutaneous leishmaniasis caused by L. braziliensis in Colombia,[2] and preliminary results are very promising. It is now registered in many countries and is the first orally administered breakthrough therapy for visceral and cutaneous leishmaniasis.[6](More, et al, 2003). In October 2006 it received orphan drug status from the US Food and Drug administration. The drug is generally better tolerated than other drugs. Main side effects are gastrointetinal disturbance in the 1-2 days of treatment which does not affect the efficacy. Because it is available as an oral formulation, the expense and inconvenience of hospitalisation is avoided, which makes it an attractive alternative.

More info here:
http://en.wikipedia.org/wiki/Leishmaniasis#Treatment  (+ info)

Cutaneous leishmaniasis symptoms?


Any good links on how you can tell if you have the cutaneous version of this? Thank you.
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After getting bitten by a sandfly, disease may manifest itself from a week to many months later.

It starts out as a papule that enlarges to an ulcer. The ulcer can give the appearance of a volcano crater. Lesions may appear singly or multiple; many heal spontaneously within weeks to months to years.
See more here: http://www.examiner.com/x-7707-Infectious-Disease-Examiner~y2009m7d11-Travel-health-leishmaniasis  (+ info)

What is leishmaniasis? and how do i get checked? Can i die from it?


go to this website : http://www.cdc.gov/ncidod/dpd/parasites/leishmania/factsht_leishmania.htm

It has alot of info, and from what I've read you won't die from it. Just get it treated. Hope I helped a little!  (+ info)

Leishmaniasis (medical)?


I am allergic to sand flies and recently i heard about Leishmaniasis, but I cannot find any good information on it. Does anyone know websites? or are there any Doctors who could explain a little more?
I became allergic to sand flies 2007 after being biten when in Grenada (west indies), last year i was biten in Florida and i had the same allergic reaction. I have noticed an ulcer that i have had for a couple of months
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It is a nasty disorder passed on by sandflies. Mostly it is a disease of the developing world, india, pakistan and south america. It can leave some skin scarring as well as causing massively swollen spleen and fever.

Using a good insect repellant will protect you  (+ info)

Leishmaniasis?


I am doing some research on this disease, particularly Canine Leishmaniasis. I know that it is a zoonotic that can be transmitted by sand-flies, but I have heard that it can also be transmitted to humans by direct contact with an infected animal. I would like to know if this is true. I've only read this from one source so far, but I'm reluctant to believe everything that I read (especially on the internet). Thanks.
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Is Leishmaniasis curable?


Leishmaniasis is a parasitic disease spread by the bite of the sandfly. The disease is called Kala-azar and can indeed be fatal! It presents with d+vs and then fatigue it may also present with destructive skin lesions.

Antimony-containing compounds are the principal medications used to treat leishmaniasis. These include:Meglumine antimonate,Sodium stibogluconate.Pentamidine and Amphotericin B are also used.  (+ info)

how to solve cameroons problems?


HIV/AIDS
dengue fever
filariasis, leishmaniasis, malaria, meningitis, schistosomiasis, and sleeping sickness
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