FAQ - Leukemia, Myeloid
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My dad was diagnosed with acute myeloid leukemia, we are considering chemo and stem cell, which one is better?


He is treated in a Hospital in Australia at the moment.. any suggestion?
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why is there high amount of vitamin B12 in patients suffering from chronic myeloid leukemia?


i am looking for pathophysiology of this?
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You might go here and ask:

http://www.newcmldrug.com

There are a lot of very knowledgeable people posting there. They have answered a lot of CML questions for me.  (+ info)

Why is World Health organization interested in classifying Acute Myeloid Leukemia ?


Because different types of Acute Myeloid Leukemia have different symptoms, treatment and prognosis.

"The World Health Organization (WHO) classification of acute myeloid leukemia (AML) incorporates and interrelates morphology, cytogenetics, molecular genetics, and immunologic markers in an attempt to construct a classification that is universally applicable and prognostically valid.["  (+ info)

Does anyone have any experience with Acute Myeloid Leukemia?


I sort of understand what it is, but not the treatment part of it. My cousin will be getting chemo for 10 days...but that's all I know...? Do you know anything else done for it? Bone Marrow transplant, etc?
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well i don't know a lot, but my friend had leukemia and he had to get a bone marrow transplant and was on chemo forever. that's all i can say.  (+ info)

Are some groups more susceptible to Acute Myeloid Leukemia or do some groups experience this disease different?


I really need help!!! it's for my science project!! looked eveywhere
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There is some geographic variation in the incidence of AML. In adults, the highest rates are seen in North America, Europe, and Oceania, while adult AML is rarer in Asia and Latin America. In contrast, childhood AML is less common in North America and India than in other parts of Asia. These differences may be due to population genetics, environmental factors, or a combination of the two.

The incidence of AML increases with age; the median age at diagnosis is 63 years. AML accounts for about 90% of all acute leukemias in adults, but is rare in children. The rate of therapy-related AML (that is, AML caused by previous chemotherapy) is rising; therapy-related disease currently accounts for about 10–20% of all cases of AML. AML is slightly more common in men, with a male-to-female ratio of 1.3:1.

A hereditary risk for AML appears to exist. There are numerous reports of multiple cases of AML developing in a family at a rate higher than predicted by chance alone. The risk of developing AML is increased threefold in first-degree relatives of patients with AML. Several congenital conditions may increase the risk of leukemia; the most common is probably Down syndrome, which is associated with a 10- to 18-fold increase in the risk of AML.  (+ info)

How long does treatment for Acute Myeloid Leukemia take?


6-7 months. Induction chemo (hospitalized, sterile environment, your immune system is basically zeroed by the chemo so you need to be super super careful not to get an infection, that's why they keep you in the hospital...for weeks or months, can't remember). Then consolidation sessions -the patient comes in and has chemo then goes home same day.  (+ info)

what are the chances of surviving chronic myeloid leukemia when you are in the chronic stage of the illness?


Chronic myeloid leukemia are treated over years, and occur most often in the senior (over 65 yr old) population. About 4 yrs ago, I met a 24 yr old who had it, and his oncologist sent him to University of Chicago for research and treatment.
I think the survival rate is good for the long term. Its so good, we rarely see these patients in the hospital Onco units. They are treated as out patients by their physicians and Oncologist and follow up regularly to keep an eye on the disease.
I imagine you would like to know how long the survival is since its a chronic disease, its very hard to say.  (+ info)

Is "Chronic Myeloid Leukemia" communicable or an infectious disease? Can a normal person marry CML patient?


Like all cancers, CML is neither contagious nor infectious. And yes, a healthy person can safely marry a CML patient. I wish you the best in your marriage!  (+ info)

Is Acute Myeloid Leukemia a harmful disease?


I really need help!!! it's for my science project i looked everywhere!!!!!
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Of course. This is a type of cancer that affects the bone marrow. Here is more info:
http://www.nlm.nih.gov/medlineplus/ency/article/000542.htm  (+ info)

What's the usual treatment for pediatric AML (Acute myeloid leukemia)?


My 2 1/2 year old son E was diagnosed with a Wilms' Tumour as a newborn, won his battle, and was recently diagnosed with Secondary Acute Myelogenous Leukemia (AML). His cancer is most likely a secondary cancer caused by the chemotherapy his first time when he fought Wilms. E somehow passed his screenings he has every 3 months back in October but in the end of November we started to notice he wasn't quite himself, and he was diagnosed December 19th.

Treatment varies depending on the subtype of AML present in the child. Treatment is individualized to the patient. Typically, it consists of an induction chemotherapy (1-3 rounds), and when remission is achieved consolidation chemo is given. Treatment is individualized to the subtype of AML. Consolidation chemo is typically 3 rounds of a high dose of ara-C. I don't know how consolidation chemo goes for other patients but my son's protocol involves 7 days in-patient chemo and 21 days to recover. He had 3 rounds of induction chemo (2 failed rounds and finally a successful 3rd attempt) and he had 3 rounds of consolidation chemo. His chemo was supposed to be finishing up in September but he was put back on an intense chemo this past round due to a new tumour unrelated to the leukemia so depending on what it is we're not sure if he'll be able to finish chemo in September but we hope he can.

There are often delays due to low counts or infection. Delays are to be expected and thankfully E has only had his chemo delayed once due to low counts. He receives other medications before, during, and after chemo doses in order to combat the side effects. He usually takes Zofran (has also taken Ativan or Kytril but most often Zofran) to help with the nausea and vomiting caused by several of the drugs in his chemo cocktail. He also takes various pain killers to help with the bone pain he experiences.

After consolidation chemo he will most likely have a bone marrow biopsy to look for a complete remission. Hopefully then he'll receive his NED status (no evidence of disease). If this is a relapse for him he may have a bone marrow or stem cell transplant which involves a high dose of chemo and an iv infusion of donor bone marrow or stem cells and about a month in the hospital recovering. My son is on the transplant list waiting for a matching donor since none of my other children were good enough matches.

If you have any other questions or anything feel free to IM me (crazycanuck) or send me an email ([email protected]).  (+ info)

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