FAQ - Leukemia, Myeloid
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pls explain to me what is acute myeloid leukemia is all about...


and medications to it
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Angelo,
About 12,000 Americans learn they have acute myelogenous leukemia (AML) each year. People can get AML at any age. The chance of getting AML increases with age. About 1 in 5 children with acute leukemia has AML.

For specific questions, you can freely contact an Information Specialist at The Leukemia& Lymphoma Society at www.LLS.org or (800) 955-4572. The Leukemia & Lymphoma Society’sfree booklet, Acute Myelogenous Leukemia, gives more details on this disease and its treatment.

Leukemia is a type of cancer. There are 4 main types of
leukemia. Acute myelogenous leukemia (AML) is 1 of the
4 types. With AML, the leukemic cells are often referred
to as blast cells. AML starts with a change to a single cell in the bone
marrow. Marrow is the spongy center inside the bones. In most cases doctors do not know what causes a healthy cell to change to an AML cell.
You cannot catch AML from someone else.
There are different types of AML. These are called subtypes.
Doctors look at the AML cells in a patient’s marrow or
blood to identify the patient’s subtype of AML. Treatment
for AML depends on the patient’s subtype of AML.

Some changes that a person with AML may have are
• Tiredness or no energy
• Shortness of breath during physical activity
• Pale skin
• Swollen gums
• Slow healing of cuts
• Pinhead-size red spots under the skin
• Prolonged bleeding from minor cuts
• Mild fever
• Black-and-blue marks (bruises) with no clear cause
• Aches in bones or knees, hips or shoulder.

Induction therapy is the term for the first part of treatment with chemotherapy. Induction therapy is done in the hospital. Patients are
often in the hospital for 3 to 4 weeks. Some patients may
need to be in the hospital longer.

Some patients with AML can be cured. Children with AML and patients with a type of AML called acute promyelocytic leukemia (APL) are among those most often cured.

  (+ info)

Pathophysiology Case Study question about (what I think) Acute Myeloid Leukemia?


Case study that we need to answer and hoping someone could point me in right direction. Here's the info:

35 year old male complaining of anorexia, fatigue, weight loss, dyspnea on exertion and sense of abdominal fullness.

Erythrocytes 2.7 million/cu mm
Leukocytes 182,000/ cu mm
Thrombocytes 50,000/cu mm
Hematocrit 26%
Differential Count (DIFF) Lymphocytes 86% of all leukocytes

Bone Marrow Examination: A dominance of small lymphocytes (>90%). The bone marrow was so tightly packed that it was difficult to perform a needle aspiration. The spleen was also moderately enlarged, and there was a generalized lymph node enlargement.

I think it is Acute Myeloid Leukemia, but am not sure? Any help from anyone???

Thanks!
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Acute leukemia is defined as greater than 30% blasts in the bone marrow. It is not acute leukemia based on the bone marrow examination and on the peripheral blood differential which showed 86% lymphocytes.
The findings are consistent with stage IV chronic lymphocytic leukemia.  (+ info)

My sister just found out a week ago that she has Acute Myeloid Leukemia. She is 55, diabetic and has?


weight issues. I have explored it on the internet. Cannot find info on the survival rate. Can anyone help me on that?
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Because more than half of the patients who are newly diagnosed with AML are over 60, and more than a third are over 70, there is little written on the morbidity rates. To be diagnosed at age 55, while not extremely unusual is still young.

A friend of mine recently passed away after a 5 year fight with AML. While I cannot give you exact figures, nor where to find them, I was told that there was about a 50 percent 5 year morbidity rate.

Either way, cherish your time with your sister, and enjoy life to its fullest! We all are on this Earth for too short of time.  (+ info)

Diagnosed with acute myeloid leukemia?


I'm 15 years old(bday today ) and was diagnosed with AML today. I'm in the hosp right and my oncologist will cells back later to discuss things in detail. So she said I had a pre-leukemia syndrome thaT progressed into AML. So what exactly is AML? Is it treatednwith lotsnof chemotherapy ? She also mentioned something about a port? Ph any advi e or similar stories are appreciated. Thanks!!
I meant to say that my oncologist will come back later, not cells backnl later. Sorry I'm on my I-touch.
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First of all happy birthday! AML isn't such a great birthday present eh? Since you posted this question 3 days ago I'm guessing you have probably already started treatment. What you had was probably Myelodysplastic Syndrome (MDS). It used to be called pre-leukemia but that term has gone out of general use because it is not, at that stage, leukemia. Untreated, MDS will likely advance into AML leukemia.

AML is a cancer of the bone marrow that produces blood cells. The cancerous cells essentially push out the healthy bone marrow cells and take over producing ineffective or even cancerous blood cells. The typical treatment is chemotherapy. Depending on the subtype you have been diagnosed with your chemotherapy cocktail may be different from that of my son's. I can give you more information on drug cocktails' effects if you would like, or if I can't help you there I know lots of people that could.

My 2 1/2 year old son E was diagnosed with a Wilms' Tumour as a newborn, won his battle, and was recently diagnosed with Secondary Acute Myelogenous Leukemia (AML). His cancer is most likely a secondary cancer caused by the chemotherapy his first time when he fought Wilms. E somehow passed his screenings he has every 3 months back in October but in the end of November we started to notice he wasn't quite himself, and he was diagnosed December 19th.

E had a cold last November that he just couldn't kick. We took him to the doctor and he was given an antibiotic. We were also told that he was anemic so he was given an iron supplement. He got a little better but as soon as he finished the antibiotic he got sick again. He usually has a couple bruises here and there since he is a 2 year old. His walking was greatly affected from one of the drugs in his first chemo cocktail so he trips and falls pretty often. But the bruising he had was more than usual - he bruised at the slightest bump. That's when we really knew something was wrong and took him to the doctor again. He was admitted while his bloodwork was running so he could be hydrated since he refused to eat or drink. His oncologist came to talk to my wife and I and told us that his counts were way off normal, we knew he was at risk for developing a secondary cancer but didn't think it would really happen to him. His oncologist said there were some leukemic-looking cells in his CBC and that a bone marrow biopsy would confirm a diagnosis.

Once he was diagnosed we found out that his spleen and liver were enlarged - also symptoms of leukemia. Due to the extent of enlargement of his spleen, he had it removed after a round of chemotherapy, and at the same time he had a port put back in his chest. The port, in my opinion, is an excellent device. It makes chemo so much easier to give, there isn't the time taken up or the pain of searching for a vein. It's just a small surgically-implanted balloon-like object placed in the chest that goes into the vena cava vane. You really can't tell it's there when he has a shirt on.

He had 3 strong doses of induction chemo and 6 consolidation rounds, he was given another 2 strong doses of chemo due to a tumour in his liver that was removed last month and typed as a new cancer - a Hepatoblastoma. He has since finished his 3rd round of that. He does stay in the hospital during his chemo. His chemo lasts 7 days and he usually stays for up to 2 weeks. He will also have a bone marrow transplant when a donor becomes available. The chances of relapse with AML are pretty high. Since this is his second time fighting cancer he is considered at a greater risk for relapse so the bone marrow transplant is the best choice for him. Your oncologist may talk to you about the option of the bone marrow transplant.

There are often delays due to low counts or infection. Delays are to be expected and thankfully E has only had his chemo delayed once due to low counts. He receives other medications before, during, and after chemo doses in order to combat the side effects. He usually takes Zofran (has also taken Ativan or Kytril but most often Zofran) to help with the nausea and vomiting caused by several of the drugs in his chemo cocktail. He also takes various pain killers to help with the bone pain he experiences. He has had several blood transfusions when his counts get too low.

I think I'm about out of room here and I hope this helped you out some. If you have any more questions feel free to email me ([email protected]) or IM me (crazycanuckj).  (+ info)

is there a cure for chronic myeloid leukemia (CML)?


can herbal treatment cure CML? can herbal treatment complement glivec intake? if yes, what kind of herbal treatment that can cure or complement glivect intake? what to avoid for CML patients taking glivec?
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Bone marrow transplantation is clearly curative. In fact, it is the only proven cure for chronic myeloid leukemia, even now. However, only 30% to 40% of patients with chronic myeloid leukemia have an appropriate donor. Beyond that, the mortality (death rate) from the procedure ranges from 20% to 30%, depending upon the age of the recipient. Finally, this procedure is extremely expensive. Nevertheless, bone marrow transplantation has been the treatment of choice for chronic myeloid leukemia since the 1970s. In retrospect, it is interesting to recall that at the time this therapy was being developed, we thought the cure of this disease was not a result of the transplantation itself. Rather, we believed the cure came from the high doses of chemotherapy and radiation that were given to suppress the immune (protective) system and thereby prepare the patient's body to accept the transplant.. there is no herb that will cure leukemia...  (+ info)

Does Acute Myeloid Leukemia affect you long-term?


please help me I looked eveywhere!!! ASAP!! please

thans
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Of 77 survivors (median follow-up duration, 16.7 years), 44 (group A) had received chemotherapy, 18 (group B) had received chemotherapy and cranial irradiation, and 15 (group C) had received chemotherapy, total-body irradiation, and allogeneic bone marrow transplantation.

Growth abnormalities were found in 51% of survivors, neurocognitive abnormalities in 30%, transfusion-acquired hepatitis in 28%, endocrine abnormalities in 16%, cataracts in 12%, and cardiac abnormalities in 8%.
Younger age at the time of diagnosis or initiation of radiation therapy, higher dose of radiation, and treatment in groups B and C were risk factors for the development of academic difficulties.  (+ info)

is acute myeloid leukemia a painful disease? ?


hw for project need help ASP!! please thanxx :))
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Not terribly. It's terrible yes, but not one of the more intense pains.  (+ info)

Can you get periods if you have leukemia?


I was recently diagnosed with acute myeloid leukemia. I'm almost around that time of the month... or at least I should be. Is it possible to get periods when you have leukemia?
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This is something you need to discuss with your doctors. Your body will probably continue to menstruate. However, you need to make sure your doctor knows when your cycle is, and when your period starts. If your blood counts are too low, specifically your platelet counts, they may not want you having much of a period because you will bleed too much and may give you meds. If you start having vaginal bleeding at a time when you know it shouldnt be your period, make sure you tell the docs, because its probably a result of a super low platelet count.

I was on depo through most of my treatment, and it completely stopped my periods. But, that was more my choice than the docs. I needed a birth control method that was highly reliable and not dependant on me taking a pill at the same time every day. The lack of a period was more of an added benefit for me.  (+ info)

Chronic Myeloid Leukemia?


Ok.. just a couple quick questions- recently a member of my family was diagnosed with this disease... as of right now here white blood cells are normal but she has an extremely high platelet count. They have already done a bone marrow test- and she has the philadelphia chromosome. Does this make sense to anyone out there? Shouldnt her white blood cells be way to low/high as well
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In Chronic Myeloid Leukemia, normal blood cell production is completely replaced by leukemic cells, which however still function normally. It can occur at any age but the peak incidence is at the age of 40-60 yrs. The only predisposing factor is irradiation like in patients who receive radiotherapy. The most characteristic feature of this disease is the demonstration of Philadelphia chromosome in the leukemic blasts ( Ph-positive ) which is present in over 95% of cases. The Total leukocyte count -above 30x10to the power of 9 per litre. 1. Initial Chronic Phase : Symptoms are alleviated by treatment. 2.Phase of transformation: Disease becomes more aggressive with enlarging spleen, rising leucocyte count or rising proportion of blast cells in peripheral blood and Ph Chromosome. Bone Pain and haemorrhages from various sites. In about 20% transformation occurs abruptly.  (+ info)

My Dad, age 81, was recently diagnosed with Acute Myeloid Leukemia. Who knows anything about the drug Mylotarg


At his age, aggressive chemotherapy is not very efffective, often resulting in death. The doctors have recommended a drug called Mylotarg. Does anybody have any experiences, or info, with this drug? Please help....
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never heared of it  (+ info)

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