FAQ - Lysosomal Storage Diseases
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What is the proper storage and thawing methods for breast milk?


I have a couple questions about the topic in the heading.

Do all breastfeeding moms have to pump their milk? I am a stay at home mom and only breastfeed I do not pump. Is it a bad thing.

What is the proper storage of pumped breast milk and how long is it good for?

What is the proper way to thaw breast milk?
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No, you don't need to pump at all! Most people do for a couple of reasons: it gives them a sense of security because if they every need to stop BFing for a few days, like because they have to go on medication for an infection or something, they know they have a store of milk that their baby can use instead of formula. Also, many moms like the freedom to ocassionally go out w/o baby for longer than a feeding period. But by no means is it bad to not do so, or do you need to do so.

You can store pumped milk in the refrigerator in regular bottles, usually for up to 7 days. You can also freeze milk in the special freezer bags they sell (the fats will stick to regular plastic containers so you should not use them) and freeze the milk for up to 3-4 months. You can combine different pumping sessions as long as you date the whole bottle with the oldest date. It is always preferable not to push the limits of storage times, just to be safe.

You can thaw breast milk in the fridge overnight, or else run it under warm (not hot) water. Once thawed, you need to use it within 24 hours

HOpe that helps!  (+ info)

What diseases would have the symptom of coughing up blood or blood in the phlegm?


This is not a symptom of my own so please don't tell me to go to the doctor, it is for a piece of work I have to do for College.

If you could tell me the name of a disease/ diseases that cause this, preferably not consumption or TB, a little about it and other symptoms it would be a massive help!
If you could also include treatment options and how serious a disease it is that would also be fantastic!



Hope you can help! Thanks!
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First: spitting up blood is clinically known as: HEMOPTYSIS (bloody sputum, spit)
Yes, pneumonia is the most likely, but......
The following is from my medical e-book (I'm a nursing student)

"Blood in the sputum (hemoptysis) is most often seen in clients with chronic bronchitis or lung cancer. Clients with tuberculosis, pulmonary infarction, bronchial adenoma, or lung abscess may have grossly bloody sputum."
Also the end stage of cycstic fibrosis will present with hemoptysis.

a biggie in the hospital is:
PULMONARY EMBOLISM
PATHOPHYSIOLOGY
A pulmonary embolism (PE) is a collection of particulate matter (solids, liquids, or gaseous substances) that enters venous circulation and lodges in the pulmonary vessels. Large emboli obstruct pulmonary blood flow, leading to decreased systemic oxygenation, pulmonary tissue hypoxia, and potential death. Any substance can cause an embolism, but a blood clot is the most common.

Pulmonary embolism is the most common acute pulmonary disease (90%) among hospitalized clients. In most people with PE, a blood clot from a deep vein thrombosis (DVT) breaks loose from one of the veins in the legs or the pelvis. The thrombus breaks off, travels through the vena cava and right side of the heart, and then lodges in a smaller blood vessel in the lung. Platelets collect with the embolus, triggering the release of substances that cause blood vessel constriction. Widespread pulmonary vessel constriction and pulmonary hypertension impair gas exchange. Deoxygenated blood shunts into the arterial circulation, causing hypoxemia. About 12% of clients with PE do not have hypoxemia.

Pulmonary embolism affects at least 500,000 people a year in the United States, about 10% of whom die. Many die within 1 hour of the onset of symptoms or before the diagnosis has even been suspected.

For clients with a known risk for PE, small doses of prophylactic subcutaneous heparin may be prescribed every 8 to 12 hours. Heparin prevents excessive coagulation in clients immobilized for a prolonged period, after trauma or surgery, or when restricted to bedrest. Occasionally, a drug to reduce platelet aggregation, such as clopidogrel (Plavix), is used in place of heparin.



A smaller one that popped up in the book:
GOODPASTURE'S SYNDROME
PATHOPHYSIOLOGY
Goodpasture's syndrome is an autoimmune disorder in which autoantibodies are made against the glomerular basement membrane and neutrophils. The two organs with the most damage are the lungs and the kidney. Lung damage is manifested as pulmonary hemorrhage. Kidney damage manifests as glomerulonephritis that may rapidly progress to complete renal failure (see Chapters 74 and 75). Unlike other autoimmune disorders, Goodpasture's syndrome occurs most often in adolescent or young adult men. The exact cause or triggering agent is unknown.

COLLABORATIVE MANAGEMENT
Goodpasture's syndrome usually is not diagnosed until serious lung and/or kidney problems are present. Manifestations include shortness of breath, hemoptysis (bloody sputum), decreased urine output, weight gain, generalized nondependent edema, hypertension, and tachycardia. Chest x-rays show areas of consolidation. The most common cause of death is uremia as a result of renal failure.

Spontaneous resolution of Goodpasture's syndrome has occurred but is rare. Interventions focus on reducing the immune-mediated damage and performing some type of renal supportive therapy.

  (+ info)

What diseases can you get from cutting yourself with a rusty knife?


This is a question from a growing nurse. I've always wondered if you really can get a disease from a rusty knife or any rust and what kind of diseases you can get.
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staph aureus and staph epidermidis are commonly found on the skin and are responsible for
most infected wounds. methicillin resistant staph aureus (MRSA) is becoming a serious
problem. tetanus (clostridium tetani) is also a possibility but is usually not a problem with superficial
cuts that bleed a lot. infected wounds not treated properly can become gangrenous (clostridium
perfringens). clostridium bacteria are anaerobic which means that require a lack of oxygen to
grow. poor circulation or elevating an infected foot may lead to gangrene due to the lack of oxygen
in the infected area. if a person touches the cut with unclean hands, e. coli could infect the wound.  (+ info)

What is the best book to make your own cold storage or cellar?


Hi, I need to make a cold storage to ferment my homebrew and wines. Can anyone recommend a good book on the subject of cold storages? Thanks.
Note - The temperature where I live is 30 degrees celsius, so yes I need some sort of air conditioning to get a more ideal temperature for fermentation (around 20 degrees).
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If you can do the carpentry, you probably don't need a book. The best site is an unheated basement but a closet can be substituted. Essentially, you build a small room and insulate it well. Add a window air conditioner in one wall. Remember that the outside portion will drip, so you need a receptacle for the water. Aren't you going to want to get the temperature down below 20 deg. C for proper fermenting, though?

I'm planning on doing something similar if I can find the right house.  (+ info)

How were these diseases prevented or cured in the 1600 to early 1700s?


Measles
Smallpox
Chickenpox
Malaria

How were some of these diseases dealt with in the 1600s? If there was no cure or anything to prevent the diseases to happen can you explain why and what resulted in these situations? Thanks!
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Inoculation was sometimes used to prevent smallpox but basically either you lived or you died. Most survived chickenpox & measles but there were those who died or were left scarred or with damage to the vision or nervous system. Malaria was a disease of the tropics and is found in parts of Africa, Asia, the Middle East, Central and South America, Hispaniola, and Oceania. Mostly people died.

The 1600s were in the 17th century & the 1700s were in the 18th century. Do some online research.  (+ info)

What are some diseases similar to tuberculosis and could be mistaken as Tuberculosis?


So I am researching tuberculosis, and I have to answer the question:

If it isn't your exact disease, what else could it be?

So essentially I have to find diseases with the same signs and symptoms, ones that may act in the same way or cause your body to look the same way as tuberculosis.

I then have to talk about how they are similar and why. Any help would be great. Thanks.
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So other mycobacterium would look the same on stains:
Mycobacterium bovis
Mycobacterium kansasii
and other mycobacteria

Other bacteria can cause similar lung disease (but look different on stain and culture):
Nocardia
Rhodococcus equii
and other bacteria
  (+ info)

What kinds of diseases can you get from using a public restroom?


I've always heard that you can catch diseases from sitting on public toilets but no one has ever told me what kind you can get.
So I'm curious what kind of diseases have people gotten from using public restrooms?
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You'd have a better chance of being hit by lightning. It's almost impossible to catch any kind of disease from a toilet, for the following reasons:
1. Infections don't live long outside the body...they need a host. Toilet seats are bad hosts.
2. They need warm wet areas to live.
3. Most infections enter the body through breaks in the skin or openings...
4. Even though your anus is an opening the intestines is a hostile enviroment for infection
5. You don't sit there long enough

You CAN get skin infections...I got one. They're not deadly, just annoying.  (+ info)

What different types of heart diseases do they have?


I'm 23 & I saw a heart doctor yesterday, & so far, he told me that it doesn't look like I have heart disease from the EKG & ultrasound, but he has to run a stress test on a treadmill to see how I handle it. I get chest pains very easily simply just from walking the 1st 2 minutes. I know I'm overweight & I'm trying to lose it. But how can I if every time I try to exercise, I get chest pains? My Dr. said I'm too young for heart disease, & my PCP told me my cholesterol is a little high but not enough to be put on medication.

What kinds of heart diseases do they have? I hope I don't have it, & I'm trying to do my best to prevent it.
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I have angina and wear a nitro patch..Ask about daily aspirin..
A coated childrens asprin takes the chest pain away quickly. you dont need a prescription for spray nitro.The side efects not pleasant :; pounding head etc.  (+ info)

What diseases that can be transmitted from animals to human and vice versa?


Tell me what diseases do you know that came from animals and transmitted to us. And also what ways we can prevent it.
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There are hundreds, way too many to list here! You are referring to zoonoses, the term for a disease that can be passed from animals to humans and vice versa. Zoonoses can be parasitical, fungal, bacterial, viral, and just plain "other". They can be transmitted by cows, cats, dogs, birds, reptiles, and even fish.

Read about common zoonoses at
http://www.who.int/zoonoses/en/
http://www.anapsid.org/chomeltables.html (about pets!)

If you have access to a library, this book http://www.amazon.ca/Zoonoses-Communicable-Diseases-Common-Animal/dp/927511580X is a good source for your Question.

If you have a particular pet you are concerned about, you may want to search [pet] zoonoses.  (+ info)

What other brands of storage bags are compatible with Medela breastpumps?


I have a Medela swing breastpump and am just wondering if there are any other storage bags that work with it. The Medela bags are almost 50 cents each. If so, are the other brands just as good?
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You can use pretty much any kind of bag. Just pump into the bottle they give you and pour it into the bag.  (+ info)

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