FAQ - Motor Neuron Disease
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please tell me the symptoms and treatment for mnd(motor neuron disease?

is it any treament in tcm. give me the hospital names in singapore or in china

I'm really sorry that I can't help you with a hospital name in Singapore or China but....Here are a list of symptoms of MND

Progressive muscle weakness
Progressive muscle paralysis
Muscle groups affected depend on the type of motor neurone disease
No loss of sensation in affected areas
Difficulty swallowing
Limb weakness
Slurred speech
Impaired gait
Facial weakness
Muscle cramps

And treatment

There is no cure or standard treatment for the MNDs. Symptomatic and supportive treatment can help patients be more comfortable while maintaining their quality of life. The drug riluzole (Rilutek®), which as of this date is the only drug approved by the U.S. Food and Drug Administration to treat ALS, prolongs life by 2-3 months but does not relieve symptoms. Other medicines that may help reduce symptoms include muscle relaxants such as baclofen, tizanidine, and the benzodiazepines for spasticity; glycopyrrolate and atropine to reduce the flow of saliva; quinine or phenytoin for cramps; anticonvulsants and nonsteroidal anti-inflammatory drugs to relieve pain; tranquilizers to help with sleeping problems; antidepressants; and botulinum toxin, amitriptyline, and other anticholinergic drugs to control drooling. Some patients may require stronger medicines such as morphine to cope with musculoskeletal abnormalities or pain in later stages of the disorders, and opiates are used to provide comfort care in terminal stages of the disease.

Physical and speech therapy, occupational therapy, and rehabilitation may help to improve posture, prevent joint immobility, slow muscle weakness and atrophy, and cope with swallowing difficulties. Applying heat may relieve muscle pain. Assistive devices such as supports or braces, orthotics, speech synthesizers, and wheelchairs help some patients retain independence.  (+ info)

Are there any alternative treatments for motor neurone disease?

My mother has just been diagnosed with motor neurone disease, are there any new treatments, or alternative treatments that can help slow down the disease?

Neurobiology is improving in leaps and bounds. Stay away from the "alternative" treatments, please, as they may only make the condition worse.

I suffer from benign familial tremor and hypnogogic seizures. No "alternative" treatment has ever worked.

Newer and medications arrive monthly. Trust in your neurologist or find one you do trust.  (+ info)

Is there a cure for Motor Neurone Disease in Ayurveda?

My uncle has been diagnosed with Bulbar Onset of Motor Neurone Disease - is there a cure for this disease in Ayurveda? Do you know of anyone who has taken Ayurvedic or any other alternative therapy treatment for this disease?

This pranayam therapy will help with the motor Neurone disease.It works very gradually, so keep doing it everyday.Build up your timing gradually.If you feel tired or dizzy,stop and resume later.Once you feel the benefits, tell others.
Anulom Vilom –
Close your right nostril with thumb and deep breath-in through left nostril
then – close left nostril with two fingers and breath-out through right nostril
then -keeping the left nostril closed deep breath-in through right nostril
then - close your right nostril with thumb and breath-out through left nostril.
This is one cycle of anulom vilom.
Repeat this cycle for 20 to 30 minutes twice a day(maximum 60 minutes in one day).
You can do this before breakfast/lunch/dinner or before bedtime or in bed.Remember to take deep long breaths into the lungs.You can do this while sitting on floor or chair or lying in bed.

Kapalbhati -(Do it before eating) Push air forcefully out through the nose about once per second. Stomach will itself go in(contract in). The breathing in(through the nose) will happen automatically. Establish a rhythm and do for 20 to 30 minutes twice a day.(Max 60 min/day) Not for pregnant women. Seriously ill people do it gently.  (+ info)

What is the best treatment for muscle weakness in case of lower motor neuron injury ?

I have had a stroke in my spine and as a result lower motor injury. My legs have some strength and I can walk, however, they are weak. I would like to know if there is any treatment to get my strength up in the muscles. Exercise only makes me more tired and I do not see much of strength improvement. Are there also some medecines that I can take...

My advice to you is to keep exercising. Try walking chest deep in water to help get your weight off the injured area, and increase the amount of time you walk each time you visit the pool.

Also try doing exercises that work larger muscle groups around your injured area, any isometric exercise that uses the legs/torso should be fine. Unfortunately there is no "magic pill" to gain muscle strength or endurance so keep exercising and don't give up.  (+ info)

what is the name of that disease where you lose motor skills and their hand shakes uncontrollably?

like they are trying to wake it up from falling asleep? Is this Parkinson's disease? what causes it? Also is that Lou Gherig's disease?

Parkinson diesease causes uncontrollable shaking. This is what Michael J Fox suffers from. Lou Gherigs disease causes paralyisis, if I spelled that correct, but at any rate I,ve been around some one with Lou Gherigs and they are virtually unable to even feed themselves especially in the last stages.  (+ info)

What are the last stages of Motor Neurons Disease, possible type Progressive Bulbar Palsy?

It progresses to aspiration pneumonia, then respiratory arrest.  (+ info)

What is the link between Kennedy's disease and motor neurone disease?

I would like to know if it is a type of MND, a mutation, etc? References would be appreciated.

  (+ info)

How has Stephen Hawkin survived Motor Neurone disease?

after having it 40 years, whereas Don Revie died after having it for 2 years. Didn't they both have the same disease?

there are different strains of motor neurone disease, affecting patients differently. Stephen Hawkings has, to the best of my knowledge, lived the longest but I also knew a man who had had it for atleast 10 years. most of my regular patients died within a couple of years from aspiration pneumonia because of the bulbar paralysis (inability to speak, swallow and breathe effectively)  (+ info)

How has Stephen Hawkings managed to live all these years with that awful illness, Motor Neurone Disease?

My relation only lived 15 months from diagnosis to death. It is a living hell.

I believe he's set a record with the survival rate with Motor Neurone Disease.
Having an iron determination and first class care helps I suppose, the survival rate - About 7 in 10 people with ALS-MND die within 3-5 years of the onset of symptoms. About 2 in 10 survive 5 years, and about 1 in 10 survive 10 years or more.
I wonder if everyone gets this...
Many different problems can develop in ALS-MND. It is beyond the scope of this leaflet to list all possible situations. Most people with ALS-MND are cared for by a professional team which include neurologists, specialist nurses, physiotherapists, speech and language therapists, occupational therapists, dieticians, counsellors, etc.  (+ info)

What is the difference between a healthy neuron and one from a patient with Alzheimer's disease?

Plaques and tangles
Alzheimer's disease is named after Dr. Alois Alzheimer, a German neurologist. In 1906, he examined the brain of a woman who had died after years of progressive dementia. Her brain tissue showed abnormal clumps and irregular knots of brain cells. Today, these clumps (now called plaques) and knots (now called tangles) are considered hallmarks of Alzheimer's disease.

Studies of plaques and tangles from the brains of people who have died of Alzheimer's suggest several possible roles these structures might play in the disease. Some of the theories:

Possible role of plaques. Plaques are made up of a normally harmless protein called beta-amyloid. Although the ultimate cause of neuron death in Alzheimer's isn't known, mounting evidence suggests that a form of beta-amyloid protein may be the culprit. Three genetic mutations — in amyloid precursor protein and presenilin 1 (PS1) and presenilin 2 (PS2) proteins — are known to cause a small number of early-onset forms of Alzheimer's disease. These mutations result in the production of amyloid plaques. Together, these three genetic mutations account for less than 10 percent of all Alzheimer's cases.
Possible role of tangles. The internal support structure for brain neurons depends on the normal functioning of a protein called tau. In people with Alzheimer's, threads of tau protein undergo alterations that cause them to become twisted. Many researchers believe this may seriously damage neurons, causing them to die.  (+ info)

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