FAQ - Nephrosclerosis
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I'm suffering from Benign Nephrosclerosis. I have my BP in control right now. will i be cured? can i survive ?


I'm suffering from "Benign nephrosclerosis with focal and segmental glomerulosclerosis'. focal global sclerosis along with chronic changes in the parenchyma have set in. i'm leaking 1.6 mg % of creatinine. urine albumin is +2, 24 hrs protein- 2.18 gm. S. protein- 7.8 gm%. other reports are normal. blood-urine test after 15 days of biopsy have come almost same. my BP is under control right now. my question is, if i keep my BP under control for lifetime then also my both kidney will fail at some day? if i reduce creatiinine and albumin from urine then also my kidney will fail in future? if not then how can i know that i'm getting healed. which report suggests that i'm being cured. And on which report i should keep check. If getting worst, on which report basis i can know that my kidneys are getting severely damaged and i need didlysis. can anybody tell that by keeping atiquatte BP and creatinine, i can survive or not? and if not then what is the maximum time i have.
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I'm sorry your doctor didn't try to answer more of your questions for you, kidney problems are usually complicated and very frightening for patients when they're first diagnosed....I am not familiar with that disorder at all, but looking at the labwork you posted, it looks like so far, so good....your kidneys actually have a hand in maintaining a normal blood pressure, so that's why long-term untreated kidney disease will cause heart problems and vice versa.

It sounds like your doctor plans to keep you on a blood pressure medicine to reduce stress and possible damage to your kidneys and in the meantime monitor your BUN, creatinine, albumin, etc levels to see how well your kidneys are functioning (since the kidneys are responsible for filtering waste & unnecessary nutrients out of the blood, that labwork will tell the doctor if they're working ok).

Alot of times there isn't a "cure" for a disease...there's only treatments that maintain the health of the affected organs for as long as possible. Following your prescribed medications and having labwork drawn when ordered is the most important step because it will let you know how well the treatment is working. Since I'm not familiar with your particular diagnosis, I don't know if it is a "degenerative" disease where treatment only slows the kidney damage or if it's something that can be corrected simply by taking blood pressure pills. That's a question for your doctor! He/she gets paid a lot of money to do this job, don't be afraid to make them earn it! Write down the questions you have and call/make an appointment to sit down with your doctor and get them answered. God bless and good luck!  (+ info)

What is hypertensive nephrosclerosis?


Hypertensive nephropathy (or "hypertensive nephrosclerosis", or "Hypertensive renal disease") is a medical condition referring to damage to the kidney due to chronic high blood pressure.

It should be distinguished from "renovascular hypertension" (I15.0), which is a form of secondary hypertension.

In the kidneys, as a result of benign arterial hypertension, hyaline (pink, amorphous, homogeneous material) accumulates in the wall of small arteries and arterioles, producing the thickening of their walls and the narrowing of the lumens - hyaline arteriolosclerosis. Consequent ischemia will produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller glomeruli with different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis. In advanced stages, renal failure will occur. Functional nephrons have dilated tubules, often with hyaline casts in the lumens.  (+ info)

The left kidney shown was obtained at an autopsy of a 69 year old man... Question for the pathologist in you.?


The left kidney in the link was obtained at an autopsy of a 69 year old man. The tissue alterations most likely represents which of the following processes?

http://www.flickr.com/photos/[email protected]/4309943694/

A) Chronic analgesic abuse
B) Chronic pyelonephritis
C) Diabetic nephropathy
D) Hypertensive nephrosclerosis
E) Urethral obstruction

Please explain your reasoning, and if you can... please teach me how to see what you see. (I see fibrosis in the medulla, and maybe a massive stone).
YES!! Thank you Dr. Stephen. You just made my day! That was my guess, only I thought my ureter looked too large and medulla was too "washed out."
Your explanation of course sounds a lot more illegitimate.
Thank you again. I appreciate your time.
I'll leave the question open in case anyone else wants to teach me anything.
I am so sorry, I meant legitimate... NOT illegitimate. Again, I VERY MUCH appreciate your answer and your time.
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It looks like chronic hydronephrosis the renal tissue is thinned very extensivly suggesting bacb pressure on the kidney. So I would say "E"
Analgesic nephropathy os very uncommon these days on is more of a tubular disorder so I wouldn't expect such thinning of the cortex. Both hypertensive and diabetic renal disease are really microscopic diagnoses. S that wht I choose E  (+ info)

My daddy's autopsy report...I don't understand it.?


My daddy dies of Systemic Lupus Erythematosus, and it was a "natural" death. But I don't understand anything they gave me. I have 4 sheets of paper going into great detail, and none of it makes sense to me. Please help!

I. History of Systemic Lupus Erythematosus:
A. Bilateral Pleural Fibrous Adhesion's
B. Pedricardial and Epicardial Fibrous Adhesion's
C. Focal Peri-Splenic Adhesion's
D. Splenoegaly
E. Nephrosclerosis
F. Chronic Myocarditis and Fibrosis
G. Focal Vascultis and Periductal Inflammation in Pancreas

II. Mild Degree of Mitral Valve Stenosis with Annulus and Leaflet Calcifications

III. Chronic Obstructive Pulmonary Disease

IV. Interstitial Chronic Inflammation and Fibrosis of Kidneys

V. Postmortem Toxicology Results:
A. Atropine = positive
B. Caffeine = positive
C. Morphine - Free = 160 NG/ML
D. Citalopram/Excitalopram = 840 NG/ML
E. Cyclobenzaprine = 100 NG/ML

SOMEBODY PLEASE HELP ME! I don't know what any of this means.....I miss my daddy and want to know why he left me so early. Please help.....
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  (+ info)


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