FAQ - Tumor Lysis Syndrome
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What is "tumor lysis syndrome"?


Tumor lysis syndrome (TLS) is a very serious and sometimes life-threatening complication of cancer therapy. It can be defined as a constellation of metabolic abnormalities that results from spontaneous or treatment-related tumor necrosis. The metabolic abnormalities observed in patients with tumor lysis syndrome include hyperkalemia, hyperuricemia, and hyperphosphatemia with secondary hypocalcemia. These can lead to acute renal failure (ARF). The main principles of tumor lysis syndrome are the identification of high-risk patients, initiation of preventive therapy, and early recognition and intervention of its complications.  (+ info)

I think I have a pituitary tumor and Cushing's Syndrome. How should I bring this up to my doctor...?


without sounding like some kind of whacko that uses internet based information to self-diagnose myself. I just want her to take me seriously because I want to be tested immediately.
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Just come clean and ask if he can do some tests he will help your :)  (+ info)

my son is a 20 year old down syndrome young man. he had a non malignant tumor removed from his throat and had


a tracheostomy put in about a year ago. it has not been removed because the swelling has not gone down yet. all biopsies come back negative. and they do not know the reason for the swelling. have performed a number of tests for different conditions and nothing has come up. if any one out there could shed some light, i will be forever greatful. thank you
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I know how difficult it must be for you and your son especially when communication is compromised. It is unfortunate that tumors develop for no known reason. The underlying tumor may have triggered and autoimmune response to stimulate the sustained swelling. In some persons with Down's syndrome we can see this swelling at birth or even in early childhood with no relief and the result is a life long use of a tracheostomy. My question to you would be as to whether the ENT has attempted to utilize a 'speaking' valve so that you son can communicate with you. Have they had him seen by a speech pathologist to exercise his vocal cords to make sure that they are functioning correctly? What kind of antiinflamatory medications have the doctors prescribed? All of the answers are necessary to help give a better picture before I can make any more guesses. Sorry.  (+ info)

Can removing a tumor improve your behavior?


For example, I'm "lazy", have violent outbursts, depressed, lack a sense of humor and other things. I have frontal lobe syndrome due to brain surgeries. I was curious if I had a tumor (which is uncertain right now) if my symptoms could improve? Not asking for medical advice, just opinions.
I want to clarify I mean a brain tumor.
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How do you know if you have a brain tumor?


I get these splitting headaches and it feels like I am getting a rout canal but my dentist said my teeth are fine. It feels like my sinus in my nose cracks all the way into my brain. I am 41 and have two kids. Is it a old lady syndrome? What kind of doctor should I see? I am to young to die.
What about deep red gums. My dentist said my gums are the deepest red he has ever seen. Does he think I am bleeding in my head? Oh geez.
My headache is gone now. I feel great. Sorry for the scare.
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My Gp couldn't work out what I had ... sent me to 7 specialists till I got an MRI.
At each stage it was, "don't worry about it .. if it doesn't go away in 6 weeks, come back"
...but I said "What if I want to worry about it ... who should I see next"
I was put on a long waiting list, but then shuffled towards the front with a lump the size of a golf ball in my brain.
Keep nudging your GP to send you to the next guy
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Mine was benign  (+ info)

What is the survival rate for someone with carcinoid syndrome?


Particularly with a carcinoid tumor in the intestine that has spread to liver or has not?
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From http://www.carcinoid.org/pcf/docs/review.html
Typical carcinoids are slow growers.

In those tumors that are somewhat larger and have spread to local tissues and local lymph nodes but which, along with these locally invaded tissues, are still totally removable surgically, the average survival has been 8 years with a range up to 23 years.

Even when the tumor from the small intestine has spread in a manner that has made complete surgical removal impossible, the older statistics show that approximately one half of the patients survive an average of 5 years. Since various types of treatment have been introduced in the past decade patients appear to have an even longer survival and improved quality of life.

Atypical carcinoids, which is a group whose microscopic appearance looks different and more aggressively malignant than the typical carcinoid, follow a much more rapid course with a more uncertain outlook. An even worse forecast can be made for the very more malignant rare group called "neuroendocrine carcinoma". Atypical carcinoids can cause the Carcinoid Syndrome, but neuroendocrine carcinoma rarely do.

The tempo of the course of the illness in patients with Carcinoid Syndrome is different than that of carcinoid victims without the functioning syndrome. However, this has been remarkably improved and the outlook is much more hopeful with the advent of octreotide and similar somatostatin analogues and other new modes of treatment. In the early decades before effective treatment was available the average survival from the onset of flushing for a Carcinoid Syndrome patient was 3 years, and from the time of diagnosis was 2 years, though the range extended to over 10 years. Seventy five percent of the patients would die as a consequence of the harmful effects on the body from the excessive amounts of potent hormones released into their circulation by the tumors. Tumor growth and spread itself was fatal in only 25% of cases. In the last 10 years, since we have used effective combinations of treatment with octreotide(and similar somatostain analogues), various types of surgery, chemotherapy, hepatic artery injections and biological response mediators, the average survival time from the start of treatment (which unfortunately is often quite delayed after the diagnosis is made) has increased to almost 12 years - with a wide range often being observed.   (+ info)

Does anyone have Empty Stella syndrome ?


I have a pit tumor [ Cushing's now Addison's]. A recent MRI showed Empty Stella syndrome.
I have look it up and am going to the doctor in a couple of weeks.
I am interested in hearing from other with this.
Thanks in advance.
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As you have already read about this I request you to go the following site and get
more useful information.
The disease can be treated either with drugs or surgery.  (+ info)

What does paraneoplastic syndrome refer to?


a. the effects of substances such as hormones secreted by the tumor cells
b. severe weight loss and cachexia associated with advanced cancer
c. the decreased resistance to infection resulting from malignant tumors
d. the effects of multiple metastatic tumors
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It is a syndrome directly resulting from a malignant neoplasm, but not resulting from the presence of tumor cells in the affected parts.  (+ info)

Does anyone out there have a child born with Kerrerino syndrome; imperforate anus a genetic birth defect.?


my child was born with Kerrerino syndrome, he had imperforate anus and a tumor at the base of his spine, he came through his surgery successfully, but i am wondering how much difficulty I am going to have with his potty training.
Does anyone have any stories they could share with me about their experiences raising a child with this birth defect?
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  (+ info)

How long does it take for a brain tumor to grow and cause symptoms?


Brain Tumor or something else?
I have been experiencing buzzing and ringing in ears for about a week now! My ears also hurt and I also have headaches, nausea, tiredness, and am extremely dizzy. I had a MRI 6 months ago and everything came back negative, they found nothing. Previous to that I had a CT scan done 2 years ago and everything normal. I am a 29 year old female, with no family history of brain tumors, and was just wondering if a brain tumor could develop that fast (6 months) and cause those symptoms in that amount of time, please help?
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Just because there isn't a brain tumor doesn't mean that everything is okay. If your symptoms are bothersome, take your MRI to a neurosurgeon.

Many people go undiagnosed with a condition called chiari malformation. It causes all of the symptoms you mentioned, and several others. Just go to this website and see if it sounds like you. If it does, you'll want to be sure the neurosurgeon you see specializes in chiari.

The following link is to an informational page from the chiari institute in New York:

http://www.northshorelij.com/body.cfm?id=6409&oTopID=6458&PLinkID=6407

Best of luck to you. This condition is treatable, but not curable. But much can be done to help you, if that's what you have. Most importantly, some doctors are still uninformed and will not diagnose chiari. You need to see a specialist.  (+ info)

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