A chronic granulomatous disease. Is it possible for a child to grow out of it, later on.?
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Chronic Granulomatous Disease?
27/ F Last year I had a skin infection under my breasts. ( they looked sort of like boils)I went to the doctor and he perscribed numerous different topical and oral antiobiotics which didn't clear it up. He then sent me to a dermatologist who did a culture. It came back as Proteus Mirabilis bacteria which they said was rare. I went to an ifectious disease doctor who did bloodwork and diagnosed me w/Chronic Granulomatous Disease. He hospitalized me and put me on I/V antibiotics. It cleared up. One week later it came back. I went back in the hospital for a week and came home with a pic line to cont. for 6 weeks with i/v antiobiotics. Finally it cleared up for a month. I asked him to test me again for CGD disease and this time it came back negative. A year and a half later the infection is back again. I have had a low grade fever for the past year and a half, have "hot flashes, low energy and a general feeling of being sick. No one seems to know what is going on. How can I improve?
Chronic granulomatous disease is usually a serious disease and is generally diagnosed in childhood. It's genetic and is inherited in one of two ways - X-linked (only affects men; women can be carriers and there are some reports of a 'carrier syndrome') and autosomal recessive. It is a disorder of neutrophil function and means that you often get frequent and severe bacterial and fungal infections.
There are different diagnostic tests. The traditional test for CGD is the Nitrablue Tetrazolium test which is cheap and efficient but does not tell you what inheritance pattern you have (because it just looks at your neutrophil function). Genetic testing is possible but you would need to be tested along with close family members as there is not one single mutation but many (and it's more efficient to test for the one that runs in your family).
If you are still unwell, request a repeat test and a referral to either an Immunologist or a Geneticist. Even though your history does not sound typical, it is still possible that you have the diagnosis and it is important for your prognosis (not to mention family planning) that you know where you stand.
Your fever and rash need to be adequately treated regardless of your CGD status. They are significant symptoms and if you might require IV antibiotics, you might as well treat it promptly. (+ info
What are the homeostatic mechanisms involved in chronic kidney disease?
How does chronic kidney disease affect homeostatic mechanisms?
What is the cause and what is the effect on homeostatic mechanisms, what are the treatments?
The kidneys are regarded as homeostatic organs. If you stop and consider what the kidneys do, you'll know how chronic kidney disease affects the homeostatic functions of these organs.
I'm not sure you're wording this question correctly -- "What are the homeostatic mechanisms involved in chronic kidney disease?" -- Kidney disease doesn't implement homeostatic mechanisms...it interferes with homeostasis..
"How does chronic kidney disease affect homeostatic mechanisms?" -- As I said, stop and consider what the kidneys do and then review how chronic disease affects the kidneys.
"What is the cause and what is the effect on homeostatic mechanisms" -- Like I said...
"what are the treatments?" -- Dietary restrictions, hypertension management, diabetes management, lipid management, weight management, smoking cessation, epogen injections, diuretics, vit. D, phosphate binders management, dialysis or transplantation. Obviously, the course of treatment depends on the causes and contributory factors. (+ info
How long can you live with chronic kidney disease and what is the percentage successful transplant?
Chronic kidney disease alot of people of them but dont realize it how long can live with the disease of you slow the progression down and what is the successful transplant rate
Normal GFR is between 90 and 100. Over the age of 40, everybody's GFR reduces by 1 point each year. When GFR gets below 15, a person receives dialysis. Kidney disease can be treated with careful attention to diet, usually a low protein diet. GFR can be improved by as much as 10 points by changing to a vegetarian diet. Soy protein is good for kidney function. There are many internet sites which provide information regarding vegetarian diets etc for kidney disease. There are also various natural supplements that improve kidney function, Co-enzyme Q10 for example. As to how long you can live with kidney disease, it depends what caused it in the first place. In some cases people can live for quite a number of years before needing dialysis or transplant.
1 week ago
Why are there no symptoms between chronic and acute chagas disease?
I make a report about the disease, and I still couldn't find an answer why there are no symptoms occurring between the chronic and the acute phase, though the parasite is still in the body. Also it would be awesome if somebody knows if there is something which is triggering the illness after a couple decades so that it becomes chronic and symptoms occur.
Acute merely means it was newly diagnosed. Some diseases are considered chronic if they continue to wrsen, or you have the symptoms longer than usual. (+ info
How to know if chronic kidney disease is getting worse?
I was recently diagnosed with stage 2 chronic kidney disease and see my nephrologist every 6 months for blood work and check-ups. She said to come back earlier (next appt. is in March 2010) if I start feeling worse, but I'm not exactly sure what that means. I have been more tired and urinating alot more lately, but I'm not sure if that is considered "feeling worse"?
Is there any way that I can test my GFR at home first?
You are lucky to have caught this problem so early! First of all, for as much as doctor's visits cost, your doctor should let you call in and ask her what exactly she meant by that. Hopefully she is a kind person and discusses this with you over teh phone. If not;
You can't really test your GFR at home since it requires Techetium-99m DTPA to be injected into your veins and then multiple blood draws. However, there are other things to watch for. For example, blood int eh urine is NEVER ok! If you ever see blood inyour urine it means that the permeability of your kidneys has increased enough to let in blood cells. This is very serious and you should call your doctor immediately.
When you say you been urinating a lot more, this could be good. If it is more in volume then it is a good thing but it is only more in frequency (and not volume) then it is not good.
So, any blood in your urine, pain when urinating, or cramps before or after urinating are signs that you shuold go in earlier. (+ info
Can I have another child after being diagnosed with chronic kidney disease?
I am 22 with two children and was just diagnosed with stage 2 chronic kidney disease. My husband and I would like to have one more child down the road but I can't find any info on this. I of course will ask my nephrologist when I see her next but thought I'd get some answers on here until then.
Thanks in advance!
Chronic kidney disease probably requires medication -- correct? You need to find out if there is such a medication which is compatible with pregnancy. If you don't want to wait until you can talk to a doctor, try calling a 24-hour pharmacy and asking a pharmacist. (+ info
Has anyone heard of an association between chronic lyme disease and geographic tongue?
I have been diagnosed with chronic lyme disease, which I have had since childhood. I have also been experiencing geographic tongue since about the same time. Has anyone experienced this correlation, or know of a link between the two? Thanks.
If you've had chronic Lyme for years, it has had a huge impact on your immune system. An impaired immune system can allow all kinds of other problems--parasites, viruses, yeast, etc--to move in and set up housekeeping. Even if the Lyme didn't "cause" the tongue condition, it may well have contributed to it by battering down the immune system.
People with long-term Lyme often benefit from detoxification protocols and immune system support, in addition to whatever antibiotics you may be taking.
Good sources of info about Lyme disease:
http://www.touchedbylyme.org (+ info
Why is periodontal disease a chronic disease?
I have read a lot about periodontal disease. I understand it is an advanced stage of gum disease: accumulated plaque on your teeth and gums attacks the gum and the bone.
But plaque can be removed by professional cleaning, and good oral hygiene helps to prevent accumulation of plaque.
So, why is periodontal disease chronic then? Why can it be treated but not cured?
Periodontitis is usually chronic because it is slowly progressing. Recall that first we see gingivitis (inflammation of the gums with no active bone loss) before the bone loss (periodontitis) starts. Gingivitis can be seen fairly soon after bad hygiene starts, and usually goes away when local causative factors are removed. Periodontitis, however, takes years to start and the bone loss is slow. It happens after years of gingivitis.
When the teeth are cleaned and the plaque removed, the bone loss will stop (providing the patient improves their oral hygiene habits). This is how it is treated. Rather than saying that periodontitis is "incurable," it is better to say that it is "irreversible" since the bone does not regrow and the bone loss is permanent. But as long as the bone loss is stopped, the patient does not have periodontitis.
Hope this helps! (+ info
Do you have any eating plans for chronic kidney disease patients to gain weight?
My mother has a chronic kidney disease and she do dialysis twice a week, i can see that she is losing her weight, how can i make her gain weight?
There should be a renal dietician where your mother goes to dialysis. You should make an appt to see her.
You can get general info on recipes/diet info for renal patients at www.davita.com; look for the recipe section.
As an FYI, I was on dialysis, and never had much of an appetite during that time. It is a side effect of kidney disease. (+ info
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