FAQ - lassa fever
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Lassa Fever?


gimme some links for this Disease atleast 5 or more good ones too please.
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www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lassaf.htm

en.wikipedia.org/wiki/Lassa_fever

www.who.int/csr/disease/lassafever/en/

www.travelhealth.gov.hk/textonly/english/travel_related_diseases/lassa_fever.html

www.emedicine.com/med/byname/Arenaviruses.htm  (+ info)

What type of capsid does the does Lassa Fever have?


and it wouldn't hurt if you told me the infection mechanism, the host cell targeted, and the type of replication cycle.(:

thanks!
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Virions consist of two nucleocapsids. The nucleocapsid is filamentous and forming a closed circle; has a "string of beads" appearance with a varying length with a length of 1000-1300 nm (L segment, 450-640 nm (S segment) and a width of 3-4 nm. Nucleocapsid contains a polymerase complex and a nucleoprotein complex. Nucleocapsids are isolated nucleocapsids, free of contaminating host ribosomes organized in closed circles and display a linear array of nucleosomal subunits, so i guess its nucleocapsid

replication cycle
Lassa virus is a bisegmented, negative-strand RNA virus with ambisense coding.
The replication cycle has many targets for antivirals, although ribavirin is the only one presently in use.
The virus has effects on host chemokines

Viral life cycle

The first step in the virus life cycle is adsorption to the cell surface.

The next step is receptor-mediated endocytosis.

In the second stage of endocytosis, virus particles are surrounded by endocytic vesicles

Virus particles are uncoated at the surface of the endosome, ejecting the ribonucleoprotein from the virion and beginning the task of virus transcription.

host cell targeted

the liver is a major target organ of Lassa virus. so i guess its liver cells

infection mechanism

There are a number of ways in which the virus may be transmitted, or spread, to humans. The Mastomys rodents shed the virus in urine and droppings. Therefore, the virus can be transmitted through direct contact with these materials, through touching objects or eating food contaminated with these materials, or through cuts or sores. Because Mastomys rodents often live in and around homes and scavenge on human food remains or poorly stored food, transmission of this sort is common. Contact with the virus also may occur when a person inhales tiny particles in the air contaminated with rodent excretions. This is called aerosol or airborne transmission. Finally, because Mastomys rodents are sometimes consumed as a food source, infection may occur via direct contact when they are caught and prepared for food.

am not so sure if this is helpful but i hope it helps. and cos its your homework you will elaborate more.thanks  (+ info)

Is lassa fever caused by a virus or a bacteria?


I don't really know but that diseas is from West African and its very dangerous BE CAREFUL!!!
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Virus  (+ info)

Doctor: I'm afraid you have Lassa Fever, Hepatitis A and AIDS, and all we can feed you is?


Pancakes and Dover Sole

Patient: Will that help me Doc ?

Doctor: I have absolutely no idea, but it's all we can slip under the door.
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lol.. Like it..  (+ info)

Lassa Fever Incidence?


can someone help me find a good incidence for lassa fever?thank you.
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  (+ info)

how do i find news for lassa fever?


its a disease ( viral illness)
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The World Health Organisation collects data on disease outbreaks.

http://www.who.int/csr/don/archive/disease/lassa_fever/en/  (+ info)

What is the longest a fever can last in children?


My 9 year old son has been running a fever for almost 4 days now. He's been on antibiotic for 3 full days but still has temperature unless I give him a fever reducer. They say that you shouldn't give a fever reducer unless the temperature reaches above 102 (he's been getting 101 and 102). I am getting more and more concerned that the antibiotic is not working and it may be something more serious. It's been 72 hours and to my experiece, antibiotics usually take effect after 42 hours, tops, where there is no fever. Does anyone know how long a fever can go on for and if I should be concerned and take him in for another visit?
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Antibiotics can take up to 7 days to work. Don't be afraid to give him a fever reducer (over the counter kind), for goodness sake, the poor kids is suffering!
Yes take his back to the Doc. ASAP! Maybe get a second opinion.  (+ info)

How long does a fever typically last without use of antibiotics?


I have a fever. I'm pretty sure it is from my wisdom tooth being infected. I will be getting it removed in about three weeks (I'd do it sooner but I want to wait until I'm done with school so I can be at home and be relaxed)

If I don't take antibiotics, how long will it take for a fever to go away? I got a fever on Saturday and it's getting better, I think, but what is the average?
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If you have an infection, you should take antibiotics. Otherwise the fever can be very dangerous.  (+ info)

What harm does spiking a fever over 100 do to a fetus at 30 weeks?


I am 30 weeks, yesterday had a fever of 101. I have already called my OB. The fever broke with the help of Tylenol. I was just wondering what potential problem could be caused with a fever that high to my baby.
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Temperatures over around 102-103 can cause birth defects -but only in the first 12 weeks. After that heat is not teratogenic.

It does however tend to raise blood pressure, dehydration and cause other stress to both your body and the baby. But a healthy pregnancy at this point is unlikely to be effected  (+ info)

Taking antibiotics for fever - How much is considered to be an overdose?


My doctor prescribed antibiotics for fever. Blood or other tests were not performed, so this could have been viral fever. I am concerned about taking antibiotics, as the body(bacteria) may become immune to the antibiotic in the long run. Should I take antibiotics? How much is considered to be overdose and may develop immunity in the body?
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Your doctor is trained to know the difference between a virus and a bacterial infection. Testing is costly and often not necessary. ABSOLUTELY finish your meds! One of the MAIN REASONS we have created the "super-bugs" you are worried about is that people don't finish their antibiotics. If you are following directions, there should be no overdose. As far as immunity to the drug, I wouldn't worry about it. Take your meds and feel better soon. And if you don't trust your doctor, maybe you should find a new one.  (+ info)

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