FAQ - leukocyte-adhesion deficiency syndrome
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what is cellular immune deficiency syndrome?

when talking about cellular immune deficiency syndrome ,is only AIDS to be mentioned?

Cell-mediated immunity is an immune response that does not involve antibodies or complement but rather involves the activation of macrophages, natural killer cells (NK), antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. Historically, the immune system was separated into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells. CD4 cells or helper T cells provide protection against different pathogens.

Cellular immunity protects the body by:

1. activating antigen-specific cytotoxic T-lymphocytes that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;
2. activating macrophages and natural killer cells, enabling them to destroy intracellular pathogens; and
3. stimulating cells to secrete a variety of cytokines that influence the function of other cells involved in adaptive immune responses and innate immune responses.

Cell-mediated immunity is directed primarily at microbes that survive in phagocytes and microbes that infect non-phagocytic cells. It is most effective in removing virus-infected cells, but also participates in defending against fungi, protozoans, cancers, and intracellular bacteria. It also plays a major role in transplant rejection.  (+ info)

What is Acid Maltose deficiency syndrome,it affects the muscles but how?

it affects the muscles similar to MS causing organ shut down and the progression is similar to ms with different stages. eventually having constant ventilation and suction. would like to know what causes it is it maybe genetic i know maltose is effective for muscles feeding them energy but how does the acid part of the disease relate to this, is the acid attacking the maltose.

It is Acid Maltase Deficiency also known as Pompe disease. Pompe disease is one of a family of 49 rare genetic disorders known as Lysosomal Storage Diseases or LSDs. It affects an estimated 5,000 to 10,000 people in the developed world. It is VERY genetic. Pompe disease is caused by a complete or partial deficiency of the lysosomal enzyme, alpha-glucosidase (you dont have an enzyme you need). This enzyme is necessary to break down glycogen (big sugar molecules your body needs to survive) and to convert it into glucose (actual usable energy). Without this enzyme, glycogen, a thick sticky substance, accumulates in the lysosomes (sacs within the muscle cells) and leads to severe muscle degradation (breakdown). It predominately affects the heart, skeletal, and respiratory muscles of the patient. This disease attacks muscles only.

Multiple sclerosis is a chronic, inflammatory, demyelinating disease that affects the central nervous system (CNS). MS attacks your neurons affecting the way your brain communicates with your body. MS can cause a variety of symptoms, including changes in sensation, visual problems, muscle weakness, depression, difficulties with coordination and speech, severe fatigue, cognitive impairment, problems with balance, overheating, and pain. MS will cause impaired mobility and disability in more severe cases. Therefore this disease may present a little similarly when severe, but it is pretty different from acid maltase deficiency.

If you have any other questions feel free to email me. Hope this helps. Here is a couple of useful websites.


http://en.wikipedia.org/wiki/Multiple_sclerosis  (+ info)

How long should it take to recover from Chronic Fatigue Immune Deficiency Syndrome?

I was told I should be OK within 112 days. My experience tells me that's not correct.

First of all, it is true that people can recover comepletely from CFIDS. I have known people that did. However, I would be cautious about setting a time limit on your expectation. Some people are well within a year, for others it can take 3-6 years. Some people have it for much longer - I have had it for 13 years. The best thing you can do is learn to rest and take it one day at a time. Don't look too far into the future or assume you will not get well. Limit your activities to a number you can manage, make sure you do some gentle excerises when you can, and most of all don't feel bad about being ill. That's the hardest part, realizing it's not your fault and you didn't do anything to deserve it. Make sure you have people who will support you. Explore all the treatment options you can, your doctor may not be aware of all of them. If he is not helping you, keep looking until you find a doctor that does. Keep doing as much of the things you enjoy as you can, and be patient - chances are, you will get better.  (+ info)

Why do so many people think Primary immune deficiency syndrome is a psychological disorder?

umm...  (+ info)

How would I know if who between me and my husband is the carrier of G6PD deficiency syndrome?

My baby is a G6PD deficient....

  (+ info)

Why do people think that primary immune deficiency syndrome is a mental illness?

they don't know or understand it so they just label it like that. I don't know what it is, but by actually thinking about it, it sounds to me like something not being right with your immune system. It doesn't take a lot to figure out that.  (+ info)

How do you feel about Chronic Fatigue Immune deficiency syndrome? Do you believe it's real or in ones mind?

Do you believe that this is real or in the mind. It is know as ME in the UK. I would like to hear your veiws on this. Thank you.

My mum finally overcame chronic fatigue syndrome about 2 years ago. It started when she head to go into hospital as she had a severe eye infection but even when she came out of hospital she was not right. She would get tired very easily, couldnt do anything most days, even a short walk would seem like climbing everest for her. She was always ill with one thing or another, and even though as a 13 year old i thought she was just being lazy looking back now im 16 i realise that actually she was ill and it does exist. Basically she burnt herself out in work as a teacher in a difficult school and so was ill with it for over 2 or 3 years. Even now she still gets very tired and ill easily so to all of the people out there who dont believe it it is real, just go and see soemone who has it. It may well turn out to be the effects of an underlying illness that we cannot see but i definatly believe it. My sister also had a mild form of ME when she was 14 so it may be -possible for it to be genetic. I think we need to research more and have more funding available for the research to take place. It Is an illness, and one that cant be treated. As someone who has seen it happen to both of my immediate family members it really is hard to deal with, and as it is not recognised as a actuall stress born illness there is no compensation available which meant life for us over the past few years has been increadbly difficult with only my fathers small income to rely upon. I hope you or whoever you know that may be affected by it will recover soon, but it is usually long and very painfull for all who are involved. We all need to relax more, as life should be more simple than this. hope that helped, best wishes Abi xxxx  (+ info)

AIDS(Acquired immune deficiency syndrome): are there ways to prevent this?

There had been symposiums and seminars about preventive measures regarding AIDS... what are ways to avoid AIDS? How do we control AIDS?
There had been symposiums and seminars about preventive measures regarding AIDS... what are ways to avoid AIDS? How do we control AIDS? What are the signs and symptoms of it?

Celibacy will protect you perfectly. (No one ever likes that suggestion)

The other thing is condoms.

and avoid certain high risk actions, like sharing needles if you inject drugs, (you really ought to avoid that all together) and anal sex is particularly hazardous.

You must have missed the late 1980's somehow. That's when I heard all this.  (+ info)

Has anyone heard of acute immune deficiency syndrome?

No not aids this is very different.
NO NOT AIDS this is where it affects certain parts of the body like aids but not fatal, like two kinds of lupus


primary immune deficiency syndrome..This is not Aids,and children and adults can have this.Remember the movie {THE BUBBLE BOY} who lived in the bubble?There are treatments with IG therapy,infusions monthly or..more frequently.. I can't even begin to tell you all the misconceptions for this.  (+ info)

Has anyone on here got electrolyte deficiency syndrome?

Have been told I have this do know a little only sounds a bit scarey.
Thanks it was my own gp have to have my bloods checked every month and if too low in sodium am pot on fluid reduction was 11 days on a life support last year in a coma was lucky didn't end up with renal faliure or dead.
Thats strange used to have a few larger on a friday am not allowed to have alcohol, coffee, coke or energy drinks haavn't had any for over a year and it is still there levels very low. Will check that out thanks
did check out the 1 about dogs and also alcohol was correct about the dogs but can also be connected with use of antidepressants.
Thank you for your answers they were helpfull found out more of what was said when in a coma that it was most unusual for someone to ever live after how far I had gone, but did and am here although have to be very carefull seems it may have been a defect from birth and that would explain a lot of problems in my past with blood maybe if someone is as lucky as me will see this and it may help them thank you again.

No as it is more common with racing grayhounds, brought on by dehydration. Electrolyte imbalance can be caused however, by consuming large quantities of alcohol.  (+ info)

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