FAQ - parakeratosis
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what does this diagnosis mean: chronic esophagitis, moderate to severe (increased eosophils) w/ parakeratosis?

Esophagitis is inflammation of the esophagus (food pipe to stomach), eosinophils are white blood cells that generally increase to fight infection; keratosis is growth of hard hornlike tissue on the skin for example, psoriasis.
Soooooo, just a lay person guess, but sounds like you are experiencing irritation to your esophagus by hardened tissue growing there and increased white blood cells coming to area to fight infection. May not be as bad as it sounds.
Best bet is to check out website below and put in search on Google, Yahoo or Why.com.  (+ info)

upper fixed fill crownbridge lower floating denture 1 yearback.for the past 6 months white patches seen?

doctor removed surgically the white patchy portion on the ridge of the gum sent for biopsy report of biopsy---BIOPSY FROM BUCCAL MUCOSA SHOWING MARKED EPITHELIAL ACANTHOSIS AND KERATOSIS WITH FOCAL EPITHELIAL ATYPIA AND SUBEPITHELIAL ROUND CELL INFILTRATES
microscopic description--SECTIONS SHOW SEGMENT OF STRATIFIED SQUAMOUS EPITHELIUM SHOWING MODERATE DYSPLASIA WITH MARKED ORTHO AND PARAKERATOSIS WITH HYPERGRANULOSIS. pl explain what it is and what it shows and what type of treatment to be taken and the type of dental treatment to be done.

The doctor who sent the specimen for biopsy is the only one who is in a position to answer this question. Why in the world are you asking a question that _could_ be abot your LIFE on Yahoo!? ยง  (+ info)

reappearance of whitish tissue after removed white patch completely and biopsy taken report alredy given?

doctor already removed the whitsh tissue and taken biopsy report already sent toyou in my earlier question.. when he examined again slight whitish patch seen. he says skin tissue is converting to bone tissue. hence take opinin of oral pathologist and take another biopsy. MY DOUBT IS Whether is it due to upper denture permanenetly fixed without doing any rootcanal creating problems in the lips for 6 months and now affecting lower buccal mucosa slight white patches are seen even without using lower floating denture.
earlier biopsy observation sections show segment of stratified squamous epithelium showing moderate dysplasia with marked ortho and parakeratosis with hypergranulosis. IMPRESSION---BIOPSY FROM BUCCAL MUCOSA SHOWING MARKED EPITHELIALACANTHOSIS AND KERATOSIS WITH FOCAL EPITHELIALATYPIA AND SUBEPITHELIALROUNDCELL INFILTRATES
can you give a solution.I am worried since time is getting lost and landup seriously

You know, a lot of people have callouses on their elbows. You happen to have one in your mouth. It is not malignant and not invasive, so I don't understand why the repeated questions about what to do. There is no need to do anything. The doctors who have seen you say this. I have never seen you and can not determine any relationship between your upper fixed bridge and your buccal mucosa.

I'm not sure you should be trying to find answers to this on Yahoo! Answers.  (+ info)

biopsy shows spares superficial mixed infiltrate of lumphocytes and heutrophils with moderate spongiotic?

clinical diagnosis;pemphigus vulgaris?psoriasiform dermatitis

biopsy shows spares superficial mixed infiltrate of lumphocytes and heutrophils with moderate spongiotic psoriasiform change in the epidermis .the epiderms shows spongiosis with occassional neutrophils involving all layers of epidermis .the stratum shows large foci of parakeratosis and the epidemis shows a cleft above the granaluar layer with a few elongated acanthotic cells

dermatolgist remarks :consistent with pemphigus foliaceus
what actually this report indicates and what preacautions should be taken in this condition pl let me know

Pemphigus Foliaceus is the least severe of the three varieties. Desmoglein 1, the protein that is destroyed by the body's immune system is only found in the top dry layer of the skin, so mouth sores do not occur. Pemphigus foliaceus is characterized by crusty sores that often begin on the scalp, and may move to the chest, back, and face. It is not as painful as pemphigus vulgaris, and is often mis-diagnosed as dermatitis or eczema.

If not treated, pemphigus is fatal, due to overwhelming systemic infection. The most common treatment is the administration of oral steroids, especially prednisone. Recently, there has been great promise of surviving some forms of pemphigus (especially PNP) by using a pooled blood product known as gamma globulin or IVIG. Mild cases sometimes respond to the application of topical steroids. In 2007, a clinical trial including a one-week treatment with Rituximab, a monoclonal chimaeric Anti-CD20-Antibody, approved by the FDA for the treatment of B-Cell-Non-Hodgkin-Lymphoma and severe cases of rheumatoid arthritis, showed a remission in 18 of 21 otherwise untreatable, severe cases of Pemphigus vulgaris.[1][2]

All of these drugs may cause severe side effects, so the patient should be closely monitored by doctors. Once the outbreaks are under control, dosage is often reduced, to lessen side effects.

If paraneoplastic pemphigus is diagnosed with pulmonary disease, a powerful cocktail of immune suppressant drugs is sometimes used in an attempt to halt the rapid progression of bronchiolitis obliterans. Some drugs used include solumedrol, ciclosporin, azathioprine, and in rare instances, extremely controlled use of thalidomide in eligible patients. Immune phoresis procedures are also a possible treatment.

If skin lesions do become infected, antibiotics may be used for treatment. In addition, talcum powder is helpful to prevent oozing sores from adhering to bedsheets and clothes.[citation needed]

[edit] Pemphigus in domestic animals

Pemphigus foliaceus skin eruption on the ventral abdomen of a dogPemphigus foliaceus has been recognized in pet dogs, cats and horses and is the most common autoimmune skin disease diagnosed in veterinary medicine. Pemphigus foliaceus in animals produces clusters of small vesicles that quickly evolve into pustules. Pustules may rupture, forming erosions or become crusted. Left untreated, pemphigus foliaceus in animals is life-threatening leading to loss of condition and secondary infection.

Pemphigus vulgaris is a very rare disorder described in pet dogs and cats. Paraneoplastic pemphigus has been identified in pet dogs.  (+ info)

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