FAQ - pemphigus
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What is the best medicine to treat pemphigus i have heard about mestinon work miracles taken in dose of 360mg?


I KNOW YOU WANNA KNOW THE ANSWER BUT YOU ARE MAKING THE QUESTION TO HARD TO ANSWER BUT THX 4 THE POINTS  (+ info)

why sweating with dirty smell comes to neck and joints in pemphigus?


Since five years i am suffering by pemphigus ,i am using steriod,now my full body infected and dirty scraches is also everywhere including my face.
Iuse to eat occasionaly non-veg
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find out why and how your pemphigus started (using the web),
and what other treatment options are available.
Here's afew suggestions:
1) dump all of your sweets, artificial sweeteners, sodas,
2) no coffee, ice tea,
3) no junk foods;
4) start drinking hot, green tea several times/day,
5) take Omega-3 fish oils (natural blood thinner; also helps
w/ digestion),
6) eat Kosher raw sea salt (has trace minerals that help the
skin and other body functions),
7) eat more Vit. C-rich fruits and veggies, and
8) start using non-fluoride toothpaste (fluoride kills the
thyroid gland, damages the liver).
Hope these suggestions help w/ your pemphigus.
All the best to you.  (+ info)

Is there any treatment for the skin disease Pemphigus Vulgaris? How can pain from the blisters be mitigated?


I have been suffering from this disease for the last 5 years. The blisters come in all seasons. Sometimes they will come one after the other. Sometimes there will be a gap of one to two months. At a time two to three may also be there. They come mostly on the legs, thighs, buttocks and around the genital organ. It starts as a small tip, grows further until it bursts when puss and blood come out. Scars are left at the place. The blisters irritate me and interefere with my daily activities as the pain until they are cleared becomes unberable. The skin specialist whom I consulted said there is no cure and there is no medicine even for the pain. I take pain killers with the risk of the side effects involved. Is not there any treatment for this diseaase? Is there any traditional method of mitigating the pain from the blisters apart from taking antibiotics/pain killers? Experts in skin diseases or those who suffer from the same disease may please help me by sharing their knowledge/views.
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I'm sorry to hear that you are suffering. Since Pemphigus is an autoimmune disease, any treatment that supresses the over response of your immune system will improve your symptoms. Following a macrobiotic diet will signifigantly improve your immune function and it's simple to try. I've suffered for years myself with autoimmune issues untill i started following this diet and I am healthier than i ever have been. Conventional medicine is often nothing but a mask for symptoms, but lifestyle change gets at the cause of the problem. Good luck  (+ info)

I am looking for either conventional or herbal treatments for Pemphigus vulgaris?


I would like to know if there is perhaps a diet that would help improve the issue or avoid because it might agitate the condition.
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http://www.naturopathic.org/AF_MemberDirectory.asp?version=2........find a doctor in ur area on this site  (+ info)

what is the diagnosis of pemphigus vulgaris?


I had biopsy last week & want to know the diagnosis of pemphigus vulgaris can you please help me ?
Thanx in advance
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Pemphigus vulgaris is a very rare autoimmune disease. It typically begins in the mouth and can spread to other parts of your body. It is a blistering disease where you can get a number of very sore lesions. Your body is attacking some of the cell membranes of your skin which causes your skin to lose cell adhesion. The resulting blister is the equivalent of a burn and is just as painful. The age of onset of the disease is typically in your 50's but can occur in children as well. The cause is unknown. It affects people of all races but seems to be slightly higher in Jewish populations and populations from the Mediterranean region.

You will probably be prescribed high doses of corticosteroids and probably immunosuppressive drugs depending on the severity of the disease. Intravenous immunoglobulin therapy might also be used depending on your response to the other drugs.

Vitamins such as calcium and vitamin D will probably be recommended to counteract potential side effects of the steroids.

Many doctors do not know a whole lot about this disease due to its rarity. I would suggest you locate a dermatologist who has experience with it. Many of the references you will find on the web are out of date and therefore only somewhat useful.  (+ info)

Is there a sure remedy in any therapy for a permanent cure about a dreadful skin disease called "PEMPHIGUS"?


No steroid based drugs / medicines please !
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There is no cure or remedy for Pemphigus available except steroid base treatment.

The aim of treatment is to reduce inflammatory response and autoantibody production. While target-specific therapy is not available, non-target–specific treatments currently are used. The most commonly used medications are corticosteroids.


Immunosuppressive agents
Useful adjuvants in patients with PV (Pemphigus Vulgaris) with generalized disease unresponsive to steroids and/or other anti-inflammatory agents or in patients unable to tolerate prednisone.



Azathioprine (Imuran)
Antagonizes purine metabolism and inhibits synthesis of DNA, RNA, and proteins. May decrease proliferation of immune cells, which results in lower autoimmune activity. In conjunction with prednisone, it is more effective than prednisone alone. May be an effective monotherapy in mild cases, although the therapeutic effect is delayed 3-5 wk.
Consider withdrawal if no improvement within 3 mo.  (+ info)

What is the permanent remedy for the auto immune skin disease of Pemphigus Vulgaris?


Treatment for pemphigus vulgaris (PV) involves the use of one or more drugs. Initially, PV is treated with a corticosteroid. Other drugs are usually used in conjunction with corticosteroids.

Corticosteroids

Prompt and sufficient doses of corticosteroids, usually prednisone or prednisolone, are required to bring pemphigus under control. Once controlled, the steroid is reduced slowly to minimize side effects. Some patients then go into remission; however, many patients need a small maintenance dose to keep the disease under control.

Immunosuppressants

Azathioprine (Imuran®)
Mycophenolate mofetil (CellCept®)
Cyclophosphamide (Cytoxan®)
Cyclosporine
Additional Drugs

Other drugs that are used routinely with varying effects are:

Dapsone®
Gold injections
Methotrexate
Tetracycline, minocycline, or doxycycline combined with niacinamide
Biologics - several of these drugs (Rituxan, Remicade, Enbrel) are in clinical trial.

Treatment should always be addressed according to the disease activity that is clinically apparent. An indirect immunofluorescence test (antibody titer count) will generally show a high count when the disease is more active, and will be low or undetectable when the disease is in remission. However, this is not always true. The antibody titer test may be most useful with patients on maintenance doses of drugs. If a titer count is low, then it could be reassuring that the flare is controllable and short. A high titer might indicate the need for further treatment.

To date, no studies have shown that alternative, homeopathic, or any other non-traditional method has been successful in treating these diseases. For the best possible results, it is imperative that traditional treatments be administered.
However, once the disease is under control, alternative therapies may be useful to help reduce drug side effects.  (+ info)

Someone I know has been told the sores in their mouth is from pemphigus is this true??


cannot eat because of sores in the mouth, discolored tongue, bleeding during bathroom trips and pain in the lowerarea. They was hospitalized for a week but doctors are still not sure what to make of it but they are calling it Pemphigus. What should the next step be please help.
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Pemphigus is an autoimmune disorder than attacks the base layer of epithelium. Different types of pemphigus attack different places. Unfortunately, the one that attacks the mouth is especially unpleasant because it is so dang painful.

Pemphigus is treated with steroids and immune suppressants. So if the doctors know it's pemphigus, they should've already offered treatment or planned a treatment regimen.

The dermatologist will do a tissue biopsy and run some blood tests. Pemphigus is very rare, so many doctors miss it. But once they suspect pemphigus, it can be pretty easy to diagnose. She may need to see a specialist, though, and doctors specialising in pemphigus diagnosis and treatment are a little bit hard to find.

Once your friend begins steroid therapy, be sure to avoid her if you are sick, discourage her from eating raw foods (like soft cheese, sushi and vegetables), and always mind your hygiene. The drugs your friend will be on will make her very susceptible to illness. Fortunately, patients are rarely kept on the drugs for too long, so the immune system will come back eventually.  (+ info)

any good medication for ocular pemphigus?


my uncle has one eye can not open, it is ocular pemphigus,is anybody knows any good medication? thanks a lot for your help
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There are a few medications that can be used in the treatment of pemphigus. However, all of them are rather potent,and require a prescription; so it's best that he have his dermatologist and ophthalmologist control the treatment.  (+ info)

Are there any natural/herbal remedies for Pemphigus?


I agree with the first answer. It is a serious condition and would be very careful on how you go about it.
I can't think of any herbal remedies of the top of my head, there is a treatment on the medical side however that doesn't involve suppressing the immune system with steroids or other meds called plasmapheresis. As pemphigus is related to specific antibodies in the blood, with this treatment you are basically filtering out these antibodies. The treatment is usually done once every 4 weeks or so. Usually this is not a standalone treatment but it can help in reducing the dosing and side effects of the other medications.  (+ info)

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