FAQ - pheochromocytoma
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What is detected in Protein Metanephrine besides pheochromocytoma?

I'm confused about this. I guess 24 hr urine test was abnormal and she's doing this one. So does it look for various types of adrenal tumors or what?

phaeochromocytoma is a condition where you have high amounts of adrenaline in the blood. one of the causes of phaeochromocytoma is a growth or tumor (90% are benign) in the adrenal gland

one of the breakdown products of adrenaline is metanephrine which is excreted in the urine. another breakdown product you could find in the urine is the cathecolamine or VMA

with only the 24 hour urine collection test, it does not really show where the tumor is or what kind of tumor it is. if the patient is suspected to have phaeochromocytoma (ie from the abnormal urine results) the patient will have to have further investigations like having a CT or MRI or a radioisotope scan (MIBG)  (+ info)

Does anyone know of other medical conditions that mimic a pheochromocytoma?

24 Hour urine test was positive for catecholamines, episodes of increased heart rate, high blood pressure, followed by periods of no problems. MRI and MIBG scan negative for a tumor and Dr's say they have no answers. Anyone have any ideas?
wouldnt thyroid problems show in blood work? I was told thyroid was normal.

thyrotoxicosis.if thyroid hormone levels are normal ,paraneoplastic syndrome with increased catecholamines ,  (+ info)

Only if you have or know someone with a pheochromocytoma?

I would like to know what kind of symptoms you experienced before diagnosis. Please don't quote website information, as I can look that up for myself. Thank-you!

High blood pressure, temporary or permanent. Episodes of headache, sweating, and heart beating, weight loss, abdominal pain, diabetes.  (+ info)

Lungs infected with pheochromocytoma, any treatment?

My friend's mom infected with pheochromocytoma on both of her lung in early October.

It is still in the early stage, no obvious symptoms yet.

Is there any treatments to cure pheochromocytoma? And please recommend some good hospital for this type of disease.

Thank you.

Good website:

www.mayoclinic.com/health/pheochromocytoma/DS00569/DSECTION=3  (+ info)

Could them reveal Paraganglioma and Pheochromocytoma?

My previous 24-hour urine collection and blood test particularly for pheochromocytoma were said to be fine. Later one, my doctor of renal clinics ordered the following blood tests for me but I didn't know what they were for.

Among the blood tests they're:
-Bone profile
-Renal function test
-Liver function test
-Glucose (fasting)
-Chol, Trig, DHL, LDL (fasting)
-Complete blood count with differential

Could they help reveal or diagnose a pheochromocytoma or paraganglioma?

No the urine collection and previous blood tests are usually what's needed for diagnosis, the rest is just standard bloodwork.  (+ info)

do plasma free metenephrines check for anything besides pheochromocytoma? ?

I know this is mainly what is checks for but can it find other things if it's not a pheochromocytoms?

Normal plasma concentrations of metanephrines exclude the diagnosis of pheochromocytoma, whereas normal plasma concentrations of catecholamines and normal urinary excretion of metanephrines do not. Tests for plasma metanephrines are more sensitive than tests for plasma catecholamines or urinary metanephrines for the diagnosis of pheochromocytoma.
Although pheochromocytoma may be excluded by normal plasma concentrations of metanephrines, an abnormal test result does not always positively confirm the presence of a tumor. Elevated plasma concentrations of metanephrines were found in a few patients with secondary hypertension or cardiac failure. Elevated concentrations of total metanephrines have also been reported in patients with renal failure. When plasma concentrations of metanephrines are increased in the presence of either heart failure or kidney disease, additional diagnostic techniques, including imaging studies, are necessary.  (+ info)

How do you differentiate pheochromocytoma vs. panic attack?

  (+ info)

Does pheochromocytoma manifest neurological symptoms?

i know it there are episodes of anxiety and what not but does it cause seizures?

I have not heard of a pheochromocytoma case associated with seizures.
In looking this up, apparently it can happen with severe hypertension.
From http://emedicine.medscape.com/article/124059-overview
"Neurologic complications: A pheochromocytoma-induced hypertensive crisis may precipitate hypertensive encephalopathy, which is characterized by altered mental status, focal neurologic signs and symptoms, or seizures. Other neurologic complications include stroke due to cerebral infarction or an embolic event secondary to a mural thrombus from a dilated cardiomyopathy. Intracerebral hemorrhage also may occur because of uncontrolled hypertension."  (+ info)

Is anyone familiar with Pheochromocytoma,a tumor located on the adrenal gland?

Pheochromocytomas are tumors of the adrenal gland which produce excess adrenaline. Pheochromocytomas arise from the central portion of the adrenal gland which is called the adrenal medulla. The adrenal medulla is responsible for the normal production of adrenaline which our body requires to help maintain blood pressure and to help cope with stressful situations. A tumor which arises from the adrenal medulla and overproduces adrenaline can be a deadly tumor because of the severe elevation in blood pressure it causes.

Symptoms of Pheochromocytomas

The classical symptoms of pheos are those attributable to excess adrenaline production. Often these patients will have recurring episodes of sweating, headache, and a feeling of high anxiety. The following symptoms are listed from the most common to the least common:

Headaches (severe)
Excess sweating (generalized)
Racing heart (tachycardia and palpitations)
Anxiety / nervousness (feelings of impending death)
Nervous shaking (tremors)
Pain in the lower chest or upper abdomen
Nausea (with or without nausea)
Weight loss
Heat intolerance  (+ info)

Has anyone had positive or negative experiences with Pheochromocytoma -- tumor on the adrenal gland?

pheochromycytoma is a aldosterone secreting tumor of the adrenal glands. Often the first signs are high blood pressure (usually very high) and low potassium blood levels. Labs test and imaging will diagnose and it can be effectively treated. This is not a form of cancer.  (+ info)

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