Can You get ITP(Idiopathic Thrombocytopenic Purpura) from being around a person who has it?
Okay well my 2 out of 4 and one just got it and one already got treated for it. I just wanted to know if you can get it from being around her. Or from drinking from the same bottle or using the same chapstick or something. please and thanks.
Thrombotic thrombocytopenic purpura AND Yaz birth control?
My woman has Thrombotic thrombocytopenic purpura (T.T.P.) and she was given Yaz birth control. I am researching this product to be sure it will be safe for her to use. Doctor's make mistakes and people die so if anyone has any personal experience on this subject- your feedback would be greatly appreciated!!
What is idiopathic thrombocytopenia? How is it related to idiopathic thrombocytopenic purpura?
idiopathic thrombocytopenic purpura costs?
for a school research project im making a power point presenatation about ITP (idiopathic thrombocytopenic purpura ) and i need to know how much it costs to get treatments etc.i looked it up and couldn't find it. please help me!!! and don't post if you aren't sure its right. thankssss!
Well, why don't you look up prednisone and see how much that costs because that is the treatment, if treatment is even needed. Sometimes it is very mild. On the other hand sometimes the prednisone doesn't help and they have to take the spleen out so look up how much it cost to remove a spleen. THERE, that would be how to find your answer!
So in one person, it might me $0 and another might have to have the operation which could be $2000! So it all depends on how much treatment is needed.
How is ITP treated in children?
Because most children recover with no treatment, many doctors recommend just watching them carefully and taking care of the bleeding symptoms. Children don't have to go to the hospital if good care is available at home. However, some doctors recommend a short treatment with prednisone pills or intravenous infusions (given in a vein) of gamma globulin to increase the platelet count more quickly. Both medicines have some side effects.
How does ITP affect adults?
In most adults, ITP lasts much longer than it does in children. At the time of diagnosis, most adults have noticed increased bleeding and easy bruising for several weeks, or even months. In women, increased menstrual blood flow is a major sign.
Many adults have only mild thrombocytopenia. In fact, quite a few people have no bleeding symptoms. They are only diagnosed with ITP when their blood is checked for another reason and a low blood platelet count is found.
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How is ITP treated in adults?
Treatment of ITP in adults is aimed at increasing the blood platelet count. This is not the same as curing the disease. Patients may take prednisone for several weeks, even a month or longer. However, when the medicine is stopped, the platelet counts may get low again. If prednisone doesn't help enough, the spleen can be removed. The spleen makes most of the antibodies that destroy the blood platelets. It also destroys old or damaged blood cells. In an otherwise healthy young person, removal of the spleen is not a serious operation.
http://familydoctor.org/online/famdocen/home/common/blood/113.html (+ info
Does anyone know the color of the awareness ribbon for: Idiopathic thrombocytopenic purpura?
Does ITP (immune thrombocytopenic purpura) weaken your immune system?
Not by itself. The decrease in platelet count in the blood will manifest as bleeding/bruising of various types. Steroids are sometimes given to treat ITP, and they cause immunocompromise. Also, a splenectomy is often done to treat ITP, and your immune system is markedly weakened after your spleen is removed. (+ info
Idiopathic thrombocytopenic purpura ?
I had Idiopathic thrombocytopenic purpura (ITP) when I was about 2 years old. Are there any life-long effects that I should know about?
Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura. Although most cases are asymptomatic, very low platelet counts can lead to a bleeding diathesis and purpura.
Signs and Symptoms
ITP occurs most often in women over 40 years of age. It may be acute, lasting for 6 months or less, or chronic, lasting for over a year. The acute type is more often seen in children and will cure itself in more than 80% of cases. The chronic type is more commonly seen in adults and it tends to get worse as the disease progresses.
Occasionally, ITP patients suffer from bruising, nosebleeds, and bleeding gums; this is the characteristic pattern of bleeding in platelet disorders. Bleeding normally does not occur unless the platelet count is very low (below about 10,000 per mm3, compared to a normal range of 150,000–400,000 per mm3).
Subarachnoid and intracerebral hemorrhage are very serious possible complications of this disease. Fortunately, these are rare in patients who are being treated.
In many cases, the cause is not actually idiopathic but autoimmune, with antibodies against platelets being detected in approximately 80% of patients. Most often these antibodies are against platelet membrane glycoproteins IIb-IIIa or Ib-IX, and are of the IgG type. The coating of platelets with IgG renders them susceptible to opsonization and phagocytosis by splenic macrophages.
The IgG autoantibodies are also thought to damage megakaryocytes, the precursor cells to platelets, but this is thought to contribute only slightly to the decrease in platelet numbers.
When measuring the platelet count, one has to bear in mind that the "normal values" for laboratory measures are all statistical. They are defined by the upper and lower 2.5th percentile. It is therefore possible to be completely healthy but to have a decreased platelet count. There is, however, a higher chance of pathology.
The diagnosis of ITP is a clinical one and is a diagnosis of exclusion. Low platelet count can be a feature of a large number of diseases and, when serious, warrants investigation by a hematologist. Secondary causes include leukemia, medications (e.g. quinine, heparin), lupus erythematosus and some other autoimmune disorders, cirrhosis (leading to thrombocytopenia from hypersplenism), HIV, congenital causes, and antiphospholipid syndrome. A bone marrow examination may be performed on patients over the age of 60 and people who do not respond to treatment, or when the diagnosis is in doubt.
Despite the destruction of platelets by splenic macrophages, the spleen is normally not enlarged. In fact, an enlarged spleen should lead a clinician to investigate other possible causes for the thrombocytopenia.
Accelerated formation of platelets results in the presence of abnormally large platelets which are seen in a peripheral blood smear. Overall bleeding time is prolonged in these patients, but prothrombin time (PT) and partial thromboplastin time (PTT) are normal (because the problem is with the platelets, not with the coagulation cascade).
Occasionally, autoimmune hemolytic anemia and immune thrombocytic purpura may coexist, which is a condition called Evans syndrome.
Mild ITP does not require treatment. When platelet counts fall under 10,000 per microliter, or under 50,000 when hemorrhage occurs (e.g. in the digestive tract or in a severe nosebleed) treatment is generally initiated with steroids. Intravenous immunoglobulin (IVIg) is used for life threatening cases. Later, so-called steroid-sparing agents (alternatively called DMARDs) may be used. When these strategies fail, splenectomy (removal of the spleen) is often undertaken, as platelets targeted for destruction will often meet their fate in the spleen. A relatively new strategy is treatment with anti-D, an agent used in mothers who have been sensitized to rhesus antigen by a Rh+ baby, but the patient must be Rh+. Immunosuppresants like mycophenolate mofetil and azathioprine are becoming more popular for their effectiveness. Rituximab has also been used with some success for some patients.
Extreme cases (very rare, especially rare in children) may require vincristine, a chemotherapy agent, to stop the immune system from destroying platelets.
Intravenous immunoglobulin, while sometimes effective although not all patients respond, is expensive and the improvement is temporary (generally lasting less than a month). However, in the case of a pre-splenectomy ITP patient with dangerously low platelet counts, and a poor response to other treatments, IVIg treatment can increase platelet counts, making the splenectomy operation less dangerous.
Platelet transfusion is not normally recommended and is usually unsuccessful in raising a patient's platelet count. This is because the underlying autoimmune mechanism that destroyed the patient's platelets to begin with will also destroy donor platelets. An exception to this rule is when a patient is bleeding profusely, when transfusion of platelets can quickly form a platelet plug to stop bleeding. (+ info
Thrombotic thrombocytopenic purpura?
With this condition, is a exchange transfusion the only option.
Oh and I don't suffer with this. I'm doing research in to blood diseases.
Since the early 1990s, plasmapheresis has become the treatment of choice for TTP. This is an exchange transfusion involving removal of the patient's blood plasma through apheresis and replacement with donor plasma (fresh frozen plasma or cryosupernatant); the procedure has to be repeated daily to eliminate the inhibitor and ablate the symptoms. Lactate dehydrogenase levels are generally used to monitor disease activity. Plasmapheresis may need to be continued for 1–8 weeks before patients with idiopathic TTP cease to consume platelets and begin to normalize their hemoglobin. No single laboratory test (platelet count, LDH, ADAMTS13 level, or inhibitory factor) is indicative of recovery; research protocols have used improvement or normalization of LDH as a measure for ending plasmapheresis. Although patients may be critically ill with failure of multiple organ systems during the acute illness, including renal failure, myocardial ischemia, and neurologic symptoms, recovery over several months may be complete in the absence of a frank myocardial infarct, stroke, or CNS hemorrhage.
Many TTP patients need additional immunosuppressive therapy, with glucocorticoid steroids (e.g. prednisolone or prednisone), vincristine, cyclophosphamide, splenectomy or a combination of the above. Rituximab, a monoclonal antibody targeting B cells, has been successfully used to treat patients with refractory disease.
Children with Upshaw-Schulman syndrome receive plasma every two to three weeks prophylactically; this maintains adequate levels of functioning ADAMTS13.
Measuring LDH level, platlets counts and schistocytes under high power fields are used to monitor disease progression or remission.
:) (+ info
Idiopathic thrombocytopenic purpura patients who do not respond to PRETNIZON (steriods)?
My boyfriend was diagnozed in May with Idiopathic thrombocytopenic purpura as during a check up they found that he had a very low blood count, the lowest being 17. He has been on high dosages of pretnizon ( a steriod ) as well as some other medication but they have now weaned him off it because his blood count was getting a little higher and then 10 points back down again. Next week he is going for a bone marrow biopsy which I am told they will do from the front (normally in doctor shows it is in the spine but for some reason they are not doing it this way).
Can anyone tell me WHY they are doing this marrow biopsy?
The dr has informed us that it routine and that he should prepare himself for his spleen to be taken out.
Can anyone tell me what the consequences of this are?
ALSO a NEW development, he was laying on the couch and complaining of a severe headache, and after a while I looked at his face and he had a blood spot in his eye. I have looked it up and it LOOKS like a subconjunctival hemorrhage accompanied by a headache.
He is currently on the phone to the hospital (for them to determine if it is serious) but as we are in the Netherlands - and I dont speak nearly enough dutch to keep up - I was wondering if ANYONE had any advice... so that I can be prepared... or at least undestand what it going on.
ITP typically responds well to steroids. When a patient does not respond well to corticosteroids, then we start questioning the diagnosis. The doctors are most likely doing a bone marrow biopsy to be sure that they are not missing any other diagnosis that could explain his low platelets. Spleen removal is usually the next step in a patient with ITP that does not respond to steroids. This is because the spleen is an important part in the destruction of platelets in ITP and if you remove it then you will destroy less platelets. The biggest risk with spleen removal is infections in the future. Doctors usually vaccinate patients who will have their spleen removed against three bacteria (Meningococcus, Pneumococcus and Haemophilus influenzae). Even with vaccination, the patient still is at risk for serious fatal infections in the future. Infections in patients without a spleen require prompt treatment to prevent these serious complications. There are many people walking around without a spleen that are doing just fine. I don't mean to scare you.
Subconjunctival hemorrhages are not really anything to worry about and they will resolve with time. If your boyfriend develops eye pain or visual difficulties then he should see a doctor for it, because this is not typical for subconjunctival hemorrhage and suggests a more serious disease. Headaches are not typical for subconjunctival hemorrhage. (+ info
Have you or and anyone you know been affected by Thrombotic Thrombocytopenic Purpura (TTP)?
I was hospitalized in November for the disease. It was a horrible time went through chemo and apheresis. But, I have almost been in remission for 9 months now. Tell me your story and experiences.
I have treated a few patients with this illness in ICU setting. If you are sitting here and writing this then you are lucky since this carries a poor prognosis, all the best (+ info
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