Why does renal artery stenosis cause Hypertension? What is the physiology?
Stenosis is when there is a constriction (narrowing) of the renal artery, so the blood needs to work harder to push thru the part where the stenosis is. When the heart is working harder to push the blood thru it raises your BP. (+ info
what happens if blood lodges in the renal artery and blocks the flow of blood to the kidney?
and How tO prevent this ??
My blood pressure varies from 200+ over 100+ range to 80- over 40-. i am on various meds Renal artery OK?
The change can occur in an hour's time. have had meds adjusted many times. Noone seems to have a clue.
Your underlying medical condition may be affecting your blood pressure and, it sounds as if the right combination of medications have not been found for you. Your blood pressure varies minute by minute throughout the day, depending on your activity, food consumption, etc. You should be taking your blood pressure on the same arm at the same time of day each day and recording these numbers on a piece of paper. You should also be sitting quietly for at least 10 minutes before taking your blood pressure. Then, if you do this and your blood pressure is still elevated, you need to take your recorded numbers as proof to your doctor and have continued discussion about whether another change in medications may be needed to get your blood pressure under better control. (+ info
Does a renal artery blockage cause blockages in the legs?
My brother was admitted to the hospital last night after they found blockages and clots in his legs, but while there they found he had renal artery blockage and put in a stent this morning to fix that, so nothing done with the legs thus far. This Renal blockage is new to us,so no information as to how long he has had the problem. Might they do his legs or is it possible that fixing the renal artery will also fix the leg problem. Thank You, Marti
Renal artery stenosis ([RAS]; a narrowing) does not cause a 'direct' blockage anywhere. It is the result of a multi-factorial (many factors involved) disease process, similar to the disease process that creates narrowings in the leg arteries and even heart arteries.
As mentioned by "chapaton", there is a known relationship between RAS and elevated blood pressure (hypertension, or [HTN]); the kidneys being very sensitive to blood flow and having a mechanism that can help regulate blood pressure. 'If' RAS and HTN was simultaneously present, restoring the vasculature (and blood flow/volume) to the kidneys may adjust the blood pressure downward (presuming this WAS the cause; it may not have been).
More importantly, back to your question, if hypertension was present all along, there is some belief in the medical community that HTN can have a part in creating vascular lesions. Think of the blood as exerting excessive force on the inner lining (tunica intima) of the artery AS it surges forward briskly, stops and rebounds slightly before surging forward again. These movements create friction...a shearing force which, over time, can damage the normally, silky smooth epithelial lining (perhaps similar in analogy to scraping the skin). The injury healing process amounts to a raised surface (from the arterial wall, inwards towards the center of the channel), of a hardened scar tissue irregular in shape (like any skin wound would heal). No longer silky smooth, the circulating platelets erupt and attach at the site, possibly interpreting the irregular surface as a breach in the artery and therefore an attempt is made to 'plug it'. A clot then forms. Eventually, this site or multiple sites can 'clot off', blocking the flow of blood beyond this area.
IF this is the mechanism which caused the lower extremity "blockages and clots", it was a gradual process, allowing time for collateral circulation to reroute the blood supply around the area (see recent heart disease question - "What triggers the body to grow...?").
With the limited info you've provided, it appears the "blockages and clots" in the legs are in the arterial system since you say they discovered the RAS at the same time. A (IVC or inferior vena cava - venous) filter would not be applicable.
The legs will be done later, if repairable (see below), since fixing one area (the kidney) has no affect on repairing the other.
Depending on the location of the "blockages and clots", and your brothers kidney function in addition to other possible health issues, the leg problem may be fixed in one (cardiac cath lab or special procedures lab) session, two sessions, by a bypass surgery in the operating room, or not at all (such as due to extremely small vessel disease with adequate neighboring or collateral circulation). (+ info
Trace a molecule that is reabsorbed, glucose, from renal artery to the renal vein?
http://en.wikipedia.org/wiki/Renal_tubule#Renal_tubule (+ info
Brother has right renal artery stent and left femoral artery stent, which one is he being given the plavix for
His understanding is that if he dont take plavix for the rest of his life, that the stent(s) will fill up. The Drs also said that the arteries are now ok, and his veins are what is still wrong with him, but they indicate that nothing can be done, even tho its a vascular problem in his lower legs. No Dr has ever done an ultra-sound of his lower legs, only the top half at which time they found the trouble with the right renal artery and left femoral artery and rushed him to the hospital. I have tried checking online for info and what I am finding indicated plavix for the heart and also veins in the legs, to keep clots from forming. He cant afford plavix only making 960 a month from SS. I cannot believe nothing can be done for his lower legs, especially when no tests have been taken, we are getting a second opinion. I am going in thurs AM for removal of lung cancer of left upper lobe, will sure rest easier knowing its not hopeless for him. Thank you all so much. Marti
GO on line to the company that makes Plavix... I bet you can get it for free! My mother used to get allot of her meds free that way. You need proof of income, maybe tax forms, and his Dr. has to have a prescription to send in to them. TRY it.. you might get very lucky!!! Or ask the Dr. for samples of this! (+ info
can a kidney infection be a sign of Renal artery stenosis?
Has anyone had a stent put in for renal artery stenosis? Thanks,?
Many have been implanted stents for renal artery stenosis. Several of them get good control of hypertension. (+ info
Renal artery stenosis?
Had abnormal utra sound of kidney. Doctor sending me to nephrologist, may be renal artery stenosis, does anyone have information about this or has anyone been diagnosed with this?
This topic will help you out as having no symptoms carries no weight, think of future if left alone :
Alternative names Return to top
Renal artery occlusion; Stenosis - renal artery; Occlusion - renal artery; Fibromuscular dysplasia (FMD)
Renal artery stenosis is a narrowing or blockage of the artery that supplies blood to the kidney. It is caused by atherosclerosis, fibromuscular dysplasia of the renal artery wall, or scar formation in the artery. (See also atheroembolic renal disease.)
Causes, incidence, and risk factors
Renal artery stenosis is caused when atheroembolic renal disease results in narrowing of the renal artery. Fibromuscular disease, a condition more common in young women in which fibrous tissue grows in the wall of the renal artery and narrows it, is a second cause. It may also be caused when scar tissue forms in the renal artery after acute arterial obstruction or traumatic injury to the kidney.
Renal artery stenosis often causes hypertension (high blood pressure) with no other signs of its presence, and it is usually discovered in investigation for the cause of hypertension that is difficult to control. Renal artery stenosis is, in fact, among the most common causes of secondary (caused by another condition) hypertension. The disorder may also be discovered when a bruit (loud whooshing sound) over the kidney is noted on examination with a stethoscope (auscultation).
In the elderly, renal artery stenosis is most commonly associated with atherosclerotic disorders, including atherosclerotic heart disease. Atherosclerotic plaque deposits within the renal artery and causes it to become stenosed (narrowed).
Fibromuscular dysplasia is a congenital disorder involving thickening of the arterial wall and is a cause of renal artery stenosis in younger adults, particularly women 20 - 40 years old.
Renal artery stenosis may cause chronic renal failure if it affects both renal arteries or if the high blood pressure associated with this condition is prolonged or severe.
There are usually no symptoms.
Signs and tests
The blood pressure may be high, and there may be a history of high blood pressure that doesn't respond to medication or is difficult to control. A bruit may be heard on examination with a stethoscope (auscultation) over the kidney.
* A radionuclide renogram may show decreased blood flow. The value of radionuclide scanning is increased if the test is done twice: once after a dose of captopril and once without the captopril.
* An MRI, kidney CT scan, or kidney ultrasound may indicate a decreased size of the kidney, and/or a decrease in blood flow through the artery because the artery has become narrow.
* Renal arteriography shows the exact location of the stenosed (blocked) area.
This disease may also alter the results of the following tests:
* Urine specific gravity
* Urine concentration test
* Renal perfusion scintiscan
The treatment varies depending on the extent and severity of the symptoms. If the stenosis results in failure of a kidney, the second kidney may take over filtering and urine production for the body. Surgical repair of the stenosed area may be possible.
A balloon angioplasty (a radiographic procedure during which a balloon-tipped catheter is threaded through the artery) or a stent placement across the stenosis may be an alternative to surgery to open the stenosed area.
Antihypertensive medications may be needed to control high blood pressure.
Renal artery stenosis may cause eventual failure of the kidney if it progressively blocks the artery. This may result in chronic renal failure if there is only one functional kidney or if both renal arteries are affected.
Renal hypertension caused by renal artery stenosis may be difficult to treat. Surgical or balloon catheter repair often successfully opens the stenosed area. However, stenosis may recur.
* Malignant hypertension
* Chronic renal failure
Calling your health care provider
If your history indicates a high risk for renal artery stenosis, make an appointment to see your health care provider. However, decreased urine volume may be an emergency symptom indicating renal failure.
Some cases of renal artery stenosis may be prevented by avoiding smoking. (+ info
My husband has a blockage in his renal artery.?
He is going to a specialist because a test showed he possibly has 60 % stenosis in his left renal artery. Has anyone ever gone thru this? It's to see why his blood pressure is so hard to control. I'm scared for him.
ckm..will the tests for the blockage hurt..the dye one..and if he has to have a balloon thing..will that hurt??
Relax. It's usually easily treated.
Having said that, I'd be surprised if a 60% stenosis on one side was causing his BP problems. (+ info
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